Patents by Inventor SUSAN AUTIO

SUSAN AUTIO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUSTAINED RELEASE DRUG DELIVERY SYSTEMS WITH REDUCED IMPURITIES AND RELATED METHODS
    Publication number: 20240115463
    Abstract: The present disclosure relates to sustained release drug delivery systems. In some cases, a composition comprises an active pharmaceutical agent; at least one of sucrose acetate isobutyrate and a polyorthoester; an organic solvent; and 2,6-dimethylaniline, wherein the 2,6-dimethylaniline is present at a level less than 500 ppm. In some cases, a composition comprises N-oxide of active pharmaceutical agent at a level less than 1 wt %, based on weight of the composition. In some case, a composition comprises metal present at a level less than 5 ppm. Dosage forms and methods are also provided.
    Type: Application
    Filed: August 17, 2023
    Publication date: April 11, 2024
    Inventors: ANDREW R. MIKSZTAL, JUDY JOICE, SUSAN AUTIO, MARK P. DAVIS
  • Sustained release drug delivery systems with reduced impurities and related methods
    Patent number: 11771624
    Abstract: The present disclosure relates to sustained release drug delivery systems. In some cases, a composition comprises an active pharmaceutical agent; at least one of sucrose acetate isobutyrate and a polyorthoester; an organic solvent; and 2,6-dimethylaniline, wherein the 2,6-dimethylaniline is present at a level less than 500 ppm. In some cases, a composition comprises N-oxide of active pharmaceutical agent at a level less than 1 wt %, based on weight of the composition. In some case, a composition comprises metal present at a level less than 5 ppm. Dosage forms and methods are also provided.
    Type: Grant
    Filed: January 21, 2022
    Date of Patent: October 3, 2023
    Assignee: DURECT CORPORATION
    Inventors: Andrew R. Miksztal, Judy Joice, Susan Autio, Mark P. Davis
  • SUSTAINED RELEASE DRUG DELIVERY SYSTEMS AND RELATED METHODS
    Publication number: 20220273633
    Abstract: The present disclosure provides for methods of producing analgesia in a subject. In some cases, methods produce analgesia in a subject undergoing arthroscopic subacromial decompression surgery. The present disclosure also relates to improved sustained release drug delivery systems. In some cases, a composition comprises an active pharmaceutical agent; at least one of sucrose acetate isobutyrate and a polyorthoester; an organic solvent; and 2,6-dimethylaniline, wherein the 2,6-dimethylaniline is present at a level less than 500 ppm. In some cases, a composition comprises bupivacaine N-oxide at a level less than 1 wt %, based on weight of the composition. In some cases, a composition comprises metal present at a level less than 5 ppm. Dosage forms and methods are also provided.
    Type: Application
    Filed: May 13, 2022
    Publication date: September 1, 2022
    Inventors: ADRIAN NEIL VERITY, STEVEN HALLADAY, VAELING MILLER, PETER LANGECKER, DMITRI LISSIN, ANDREW R. MIKSZTAL, JUDY JOICE, SUSAN AUTIO, MARK P. DAVIS
  • SUSTAINED RELEASE DRUG DELIVERY SYSTEMS WITH REDUCED IMPURITIES AND RELATED METHODS
    Publication number: 20220273518
    Abstract: The present disclosure relates to sustained release drug delivery systems. In some cases, a composition comprises an active pharmaceutical agent; at least one of sucrose acetate isobutyrate and a polyorthoester; an organic solvent; and 2,6-dimethylaniline, wherein the 2,6-dimethylaniline is present at a level less than 500 ppm. In some cases, a composition comprises N-oxide of active pharmaceutical agent at a level less than 1 wt %, based on weight of the composition. In some case, a composition comprises metal present at a level less than 5 ppm. Dosage forms and methods are also provided.
    Type: Application
    Filed: January 21, 2022
    Publication date: September 1, 2022
    Inventors: ANDREW R. MIKSZTAL, JUDY JOICE, SUSAN AUTIO, MARK P. DAVIS
  • LONG-ACTING FORMULATIONS AND VEHICLES
    Publication number: 20220265830
    Abstract: The present disclosure provides long-acting formulations and vehicles, methods of making the same and methods of using the same.
    Type: Application
    Filed: July 17, 2020
    Publication date: August 25, 2022
    Applicant: DURECT CORPORATION
    Inventors: Susan AUTIO, Keith Edward BRANHAM, James A. FILICE, John W. GIBSON, John J. LEONARD, James MATRIANO, Whitney MORO, Michael SEKAR, Chelsea Alexandra SNYDER, Robert G. STRICKLEY, Raju SUBRAMANIAN, Felix THEEUWES, Monica TIJERINA, Jeremy C. WRIGHT, Su II YUM, Faye XU
  • LONG-ACTING FORMULATIONS OF TENOFOVIR ALAFENAMIDE
    Publication number: 20220257619
    Abstract: The present disclosure provides long-acting formulations of tenofovir alafenamide, methods of making the same and methods of using the same.
    Type: Application
    Filed: July 17, 2020
    Publication date: August 18, 2022
    Inventors: Susan Autio, Keith Edward Branham, James A. Filice, John W. Gibson, John J. Leonard, James Matriano, Whitney Moro, Michael Sekar, Chelsea Alexandra Snyder, Robert G. Strickley, Raju Subramanian, Felix Theeuwes, Monica Tijerina, Jeremy C. Wright, Su Il Yum, Faye Xu
  • Sustained release drug delivery systems with reduced impurities and related methods
    Patent number: 11400019
    Abstract: The present disclosure relates to sustained release drug delivery systems. In some cases, a composition comprises an active pharmaceutical agent; at least one of sucrose acetate isobutyrate and a polyorthoester; an organic solvent; and 2,6-dimethylaniline, wherein the 2,6-dimethylaniline is present at a level less than 500 ppm. In some cases, a composition comprises N-oxide of active pharmaceutical agent at a level less than 1 wt %, based on weight of the composition. In some case, a composition comprises metal present at a level less than 5 ppm. Dosage forms and methods are also provided.
    Type: Grant
    Filed: October 19, 2021
    Date of Patent: August 2, 2022
    Assignee: DURECT CORPORATION
    Inventors: Andrew R. Miksztal, Judy Joice, Susan Autio, Mark P. Davis
  • SUSTAINED RELEASE DRUG DELIVERY SYSTEMS WITH REDUCED IMPURITIES AND RELATED METHODS
    Publication number: 20220133595
    Abstract: The present disclosure relates to sustained release drug delivery systems. In some cases, a composition comprises an active pharmaceutical agent; at least one of sucrose acetate isobutyrate and a polyorthoester; an organic solvent; and 2,6-dimethylaniline, wherein the 2,6-dimethylaniline is present at a level less than 500 ppm. In some cases, a composition comprises N-oxide of active pharmaceutical agent at a level less than 1 wt %, based on weight of the composition. In some case, a composition comprises metal present at a level less than 5 ppm. Dosage forms and methods are also provided.
    Type: Application
    Filed: October 19, 2021
    Publication date: May 5, 2022
    Inventors: ANDREW R. MIKSZTAL, JUDY JOICE, SUSAN AUTIO, MARK P. DAVIS