Patents by Inventor Susan C. Bock

Susan C. Bock has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vaccine antigens that direct immunity to conserved epitopes
    Patent number: 10087218
    Abstract: A method of identification and elimination of immunodominant epitopes to elicit a response to secondary epitopes, especially conserved structures, is described, and applied to influenza haemagglutinin (HA). Identification of the primary epitopes in (HA), and replacement of amino acids having high LODrps with corresponding low LODrps amino acids produces an HA molecule which induces antibody responses to conserved HA residues. Modified HA molecules induce a broadly neutralizing vaccine.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: October 2, 2018
    Assignee: University of Utah Research Foundation
    Inventor: Susan C. Bock
  • VACCINE ANTIGENS THAT DIRECT IMMUNITY TO CONSERVED EPITOPES
    Publication number: 20170267729
    Abstract: A method of identification and elimination of immunodominant epitopes to elicit a response to secondary epitopes, especially conserved structures, is described, and applied to influenza haemagglutinin (HA). Identification of the primary epitopes in (HA), and replacement of amino acids having high LODrps with corresponding low LODrps amino acids produces an HA molecule which induces antibody responses to conserved HA residues. Modified HA molecules induce a broadly neutralizing vaccine.
    Type: Application
    Filed: October 21, 2016
    Publication date: September 21, 2017
    Inventor: Susan C. Bock
  • Vaccine antigens that direct immunity to conserved epitopes
    Patent number: 9512182
    Abstract: A method of identification and elimination of immunodominant epitopes to elicit a response to secondary epitopes, especially conserved structures, is described, and applied to influenza haemagglutinin (HA). Identification of the primary epitopes in (HA), and replacement of amino acids having high LODrps with corresponding low LODrps amino acids produces an HA molecule which induces antibody responses to conserved HA residues. Modified HA molecules induce a broadly neutralizing vaccine.
    Type: Grant
    Filed: December 12, 2011
    Date of Patent: December 6, 2016
    Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventor: Susan C. Bock
  • VACCINE ANTIGENS THAT DIRECT IMMUNITY TO CONSERVED EPITOPES
    Publication number: 20130315929
    Abstract: A method of identification and elimination of immunodominant epitopes to elicit a response to secondary epitopes, especially conserved structures, is described, and applied to influenza haemagglutinin (HA). Identification of the primary epitopes in (HA), and replacement of amino acids having high LODrps with corresponding low LODrps amino acids produces an HA molecule which induces antibody responses to conserved HA residues. Modified HA molecules induce a broadly neutralizing vaccine.
    Type: Application
    Filed: December 12, 2011
    Publication date: November 28, 2013
    Inventor: Susan C. Bock
  • Variants of antithrombin III
    Patent number: 7482139
    Abstract: Disclosed are compositions and methods related to variant antithrombin III molecules.
    Type: Grant
    Filed: June 2, 2003
    Date of Patent: January 27, 2009
    Assignee: University of Utah Research Foundation
    Inventors: Susan C. Bock, Adrian N. Hobden
  • Human antithrombin IIIs and methods related thereto
    Patent number: 6878813
    Abstract: The present invention discloses modified antithrombin III compounds and methods. The amino acid compounds of the present invention are useful in treating blood clotting disorders, as well as other disease states associated with enzymes in the coagulation pathway.
    Type: Grant
    Filed: December 11, 2001
    Date of Patent: April 12, 2005
    Assignees: Temple University - of the Commonwealth System of Higher Education, University of Utah Research Foundation
    Inventors: Susan C. Bock, Veronique Picard, Pedram Zendehrouh
  • Human antithrombin III
    Patent number: 4632981
    Abstract: Human antithrombin III (AT III) as a product of genetically altered cell culture.
    Type: Grant
    Filed: February 1, 1985
    Date of Patent: December 30, 1986
    Assignee: Genentech, Inc.
    Inventors: Susan C. Bock, Richard M. Lawn
  • Human antithrombin III
    Patent number: 4517294
    Abstract: A DNA sequence encoding human antithrombin III, cloning vehicles and cells containing that DNA sequence.
    Type: Grant
    Filed: July 30, 1982
    Date of Patent: May 14, 1985
    Assignee: Genentech, Inc.
    Inventors: Susan C. Bock, Richard M. Lawn