Patents by Inventor Susan D. Broz

Susan D. Broz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Agonist antibodies against the flk2/flt3 receptor and uses thereof
    Patent number: 5997865
    Abstract: Agonist antibodies are disclosed which bind to the extracellular domain of the flk2/flt3 receptor and thereby activate the intracellular kinase domain thereof. The labeled antibodies are useful as diagnostics for detecting the presence of the flk2/flt3 receptor in primitive hematopoietic cells for example. The antibodies are able to cause primitive hematopoietic cells to proliferate and/or differentiate and thereby enhance repopulation of mature blood cell lineages in a mammal which has undergone chemo- or radiation therapy or bone marrow transplantation. The antibodies are further useful for treating mammals which have suffered a decrease in blood cells as a consequence of disease or a hemorrhage, for example.
    Type: Grant
    Filed: May 4, 1995
    Date of Patent: December 7, 1999
    Inventors: Brian D. Bennett, Susan D. Broz, William Matthews, Francis C. Zeigler
  • Agonist antibodies against the flk2/flt3 receptor and uses thereof
    Patent number: 5635388
    Abstract: Agonist antibodies are disclosed which bind to the extracellular domain of the flk2/flt3 receptor and thereby activate the intracellular kinase domain thereof. The labeled antibodies are useful as diagnostics for detecting the presence of the flk2/flt3 receptor in primitive hematopoietic cells for example. The antibodies are able to cause primitive hematopoietic cells to proliferate and/or differentiate and thereby enhance repopulation of mature blood cell lineages in a mammal which has undergone chemo- or radiation therapy or bone marrow transplantation. The antibodies are further useful for treating mammals which have suffered a decrease in blood cells as a consequence of disease or a hemorrhage, for example.
    Type: Grant
    Filed: April 4, 1994
    Date of Patent: June 3, 1997
    Assignee: Genentech, Inc.
    Inventors: Brian D. Bennett, Susan D. Broz, William Matthews, Francis C. Zeigler