Patents by Inventor Susan D. Spencer

Susan D. Spencer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for the diagnosis and treatment of tumor
    Publication number: 20090017473
    Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: May 29, 2008
    Publication date: January 15, 2009
    Inventors: Gretchen Frantz, Kenneth J. Hillan, Heidi Phillips, Paul Polakis, Susan D. Spencer, P. Mickey Williams, Thomas D. Wu, Zemin Zhang
  • COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF TUMOR
    Publication number: 20080318239
    Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: May 12, 2008
    Publication date: December 25, 2008
    Inventors: Gretchen Frantz, Paul Polakis, Susan D. Spencer, Thomas D. Wu, Zemin Zhang
  • MONOMETHYLVALINE COMPOUNDS CAPABLE OF CONJUGATION TO LIGANDS
    Publication number: 20080248051
    Abstract: Auristatin peptides, including MeVal-Val-Dil-Dap-Norephedrine (MMAE) and MeVal-Val-Dil-Dap-Phe (MMAF), were prepared and attached to Ligands through various linkers, including maleimidocaproyl-val-cit-PAB. The resulting ligand drug conjugates were active in vitro and in vivo.
    Type: Application
    Filed: August 3, 2007
    Publication date: October 9, 2008
    Applicant: Seattle Genetics, Inc.
    Inventors: Svetlana O. Doronina, Peter D. Senter, Brian E. Toki, Allen J. Ebens, Toni Beth Kline, Paul Polakis, Mark X. Sliwkowski, Susan D. Spencer
  • MONOMETHYLVALINE COMPOUNDS CAPABLE OF CONJUGATION TO LIGANDS
    Publication number: 20080248053
    Abstract: Auristatin peptides, including MeVal-Val-Dil-Dap-Norephedrine (MMAE) and MeVal-Val-Dil-Dap-Phe (MMAF), were prepared and attached to Ligands through various linkers, including maleimidocaproyl-val-cit-PAB. The resulting ligand drug conjugates were active in vitro and in vivo.
    Type: Application
    Filed: August 3, 2007
    Publication date: October 9, 2008
    Applicant: Seattle Genetics, Inc.
    Inventors: Svetlana O. Doronina, Peter D. Senter, Brian E. Toki, Allen J. Ebens, Toni Beth Kline, Paul Polakis, Mark X. Sliwkowski, Susan D. Spencer
  • MONOMETHYLVALINE COMPOUNDS CAPABLE OF CONJUGATION TO LIGANDS
    Publication number: 20080226657
    Abstract: Auristatin peptides, including MeVal-Val-Dil-Dap-Norephedrine (MMAE) and MeVal-Val-Dil-Dap-Phe (MMAF), were prepared and attached to Ligands through various linkers, including maleimidocaproyl-val-cit-PAB. The resulting ligand drug conjugates were active in vitro and in vivo.
    Type: Application
    Filed: August 3, 2007
    Publication date: September 18, 2008
    Applicant: Seattle Genetics, Inc.
    Inventors: Svetlana O. Doronina, Peter D. Senter, Brian E. Toki, Allen J. Ebens, Toni Beth Kline, Paul Polakis, Mark X. Sliwkowski, Susan D. Spencer
  • Compositions and methods for the diagnosis and treatment of tumor
    Publication number: 20080227106
    Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: March 26, 2008
    Publication date: September 18, 2008
    Inventors: Belinda Cairns, Ruihuan Chen, Gretchen Frantz, Kenneth J. Hillan, Hartmut Koeppen, Heidi S. Phillips, Paul Polakis, Susan D. Spencer, Victoria Smith, P. Mickey Williams, Thomas D. Wu, Zemin Zhang
  • ANTIBODY-DRUG CONJUGATES AND METHODS
    Publication number: 20080171040
    Abstract: The present invention relates to antibody-drug conjugate compounds of Formula I: Ab-(L-D)pI where one or more maytansinoid drug moieties (D) are covalently linked by L to an antibody (Ab) which binds to an ErbB receptor, or which binds to one or more tumor-associated antigens or cell-surface receptors. These compounds may be used in methods of diagnosis or treatment of cancer, and other diseases and disorders.
    Type: Application
    Filed: March 21, 2008
    Publication date: July 17, 2008
    Applicant: Genentech, Inc.
    Inventors: Allen J. Ebens,, Frederic S. Jacobson, Paul Polakis, Ralph H. Schwall, Mark X. Sliwkowski, Susan D. Spencer
  • COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF TUMOR
    Publication number: 20080124739
    Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: November 20, 2007
    Publication date: May 29, 2008
    Inventors: Patrick Dowd, Gretchen Frantz, Paul Polakis, Victoria Smith, Susan D. Spencer, Thomas D. Wu, Zemin Zhang
  • Compositions and methods for the diagnosis and treatment of tumor
    Publication number: 20040241703
    Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: August 19, 2003
    Publication date: December 2, 2004
    Applicant: GENENTECH, INC.
    Inventors: Frederic J. DeSauvage, Gretchen Frantz, Kenneth J. Hillan, Paul Polakis, Andrew Polson, Victoria Smith, Susan D. Spencer, Thomas D. Wu, Zemin Zhang
  • Compositions and methods for the diagnosis and treatment of tumor
    Publication number: 20040242860
    Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: June 21, 2004
    Publication date: December 2, 2004
    Applicant: Genentech, Inc.
    Inventors: Gretchen Frantz, Kenneth J. Hillan, Heidi Phillips, Paul Polakis, Susan D. Spencer, P. Mickey Williams, Thomas D. Wu, Zemin Zhang
  • Compositions and methods for the diagnosis and treatment of tumor
    Publication number: 20040229277
    Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: June 21, 2004
    Publication date: November 18, 2004
    Applicant: Genentech, Inc.
    Inventors: Gretchen Frantz, Kenneth J. Hillan, Heidi Phillips, Paul Polakis, Susan D. Spencer, P. Mickey Williams, Thomas D. Wu, Zemin Zhang
  • Compositions and methods for the diagnosis and treatment of tumor
    Publication number: 20030228319
    Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: April 10, 2003
    Publication date: December 11, 2003
    Applicant: Genentech, Inc.
    Inventors: Gretchen Frantz, Paul Polakis, Susan D. Spencer, Thomas D. Wu, Zemin Zhang
  • Compositions and methods for the diagnosis and treatment of tumor
    Publication number: 20030228305
    Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: December 30, 2002
    Publication date: December 11, 2003
    Applicant: GENENTECH, INC.
    Inventors: Gretchen Frantz, Kenneth J. Hillan, Heidi S. Phillips, Paul Polakis, Victoria Smith, Susan D. Spencer, P. Mickey Williams, Thomas D. Wu, Zemin Zhang
  • Compositions and methods for the diagnosis and treatment of tumor
    Publication number: 20030148408
    Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: September 11, 2002
    Publication date: August 7, 2003
    Applicant: GENENTECH, INC.
    Inventors: Gretchen Frantz, Kenneth J. Hillan, Heidi Phillips, Paul Polakis, Susan D. Spencer, P. Mickey Williams, Thomas D. Wu, Zemin Zhang