Patents by Inventor Susan Doctrow

Susan Doctrow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthetic catalase/superoxide dismutase mimetics and methods for treating viral infections
    Patent number: 10683316
    Abstract: The invention provides for the treatment of disorders related to viral infection, using salen manganese compounds.
    Type: Grant
    Filed: November 9, 2012
    Date of Patent: June 16, 2020
    Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, Trustees of Boston University
    Inventors: John C. Kash, Jeffery K. Taubenberger, Rodney L. Levine, Susan Doctrow
  • SYNTHETIC CATALASE/SUPEROXIDE DISMUTASE MIMETICS AND METHODS FOR TREATING VIRAL INFECTIONS
    Publication number: 20140329792
    Abstract: The invention provides for the treatment of disorders related to viral infection, using salen manganese compounds.
    Type: Application
    Filed: November 9, 2012
    Publication date: November 6, 2014
    Inventors: John C. Kash, Jeffery K. Taubenberger, Rodney L. Levine, Susan Doctrow
  • Anti-Apoptotic Benzodiazepine Receptor Ligand Inhibitors
    Publication number: 20110136774
    Abstract: The present invention provides low molecular weight porphyrin compositions for inhibiting, preventing or delaying the binding of a ligand of a mitochondrial benzodiazepine receptor. The invention also provides pharmaceutical compositions comprising these porphyrin compositions and their use in the treatment of conditions involving the mitochondrial benzodiazepine receptor or interactions between the receptor and the mitochondrial permeability transition pore e.g., drug overdose or apoptosis including neural degeneration and radiation-induced apoptosis.
    Type: Application
    Filed: December 21, 2010
    Publication date: June 9, 2011
    Inventors: Bernard Malfroy-Camine, Susan Doctrow
  • ANTI-APOPTOTIC BENZODIAZEPINE RECEPTOR LIGAND INHIBITORS
    Publication number: 20100120738
    Abstract: The present invention provides low molecular weight porphyrin compositions for inhibiting, preventing or delaying the binding of a ligand of a mitochondrial benzodiazepine receptor. The invention also provides pharmaceutical compositions comprising these porphyrin compositions and their use in the treatment of conditions involving the mitochondrial benzodiazepine receptor or interactions between the receptor and the mitochondrial permeability transition pore e.g., drug overdose or apoptosis including neural degeneration and radiation-induced apoptosis.
    Type: Application
    Filed: September 11, 2007
    Publication date: May 13, 2010
    Inventors: Bernard Malfroy-Camine, Susan Doctrow
  • Cyclic salen-metal compounds: reactive oxygen species scavengers useful as antioxidants in the treatment and prevention of diseases
    Publication number: 20070123503
    Abstract: This invention provides antioxidant cyclic salen-metal compounds, compositions of such antioxidant cyclic salen-metal compounds having superoxide activity, catalase activity and/or peroxidase activity and methods of using such antioxidant cyclic salen-metal compositions to treat or prevent a disease associated with cell or tissue damage produced by free radicals, such as superoxide.
    Type: Application
    Filed: September 15, 2006
    Publication date: May 31, 2007
    Inventors: Bernard Malfroy-Camine, Susan Doctrow
  • Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease
    Publication number: 20060149089
    Abstract: The invention provides antioxidant salen-metal complexes, compositions of such antioxidant salen-metal complexes having superoxide activity, catalase activity, and/or peroxidase activity, compositions of salen-metal complexes in a form suitable for pharmaceutical administration to treat or prevent a disease associated with cell or tissue damage produced by free radicals such as superoxide, and cosmetic and free radical quenching formulations of salen metal compounds.
    Type: Application
    Filed: February 23, 2006
    Publication date: July 6, 2006
    Inventors: Bernard Malfroy-Camine, Susan Doctrow
  • Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease
    Publication number: 20050249796
    Abstract: The invention provides antioxidant salen-metal complexes, compositions of such antioxidant salen-metal complexes having superoxide activity, catalase activity, and/or peroxidase activity, compositions of salen-metal complexes in a form suitable for pharmaceutical administration to treat or prevent a disease associated with cell or tissue damage produced by free radicals such as superoxide, and cosmetic and free radical quenching formulations of salen metal compounds.
    Type: Application
    Filed: May 27, 2005
    Publication date: November 10, 2005
    Inventors: Bernard Malfroy-Camine, Susan Doctrow
  • Cyclic salen-metal compounds as scavengers for oxygen radicals and useful as antioxidants in the treatment and prevention of diseases
    Publication number: 20040059107
    Abstract: This invention provides antioxidant cyclic salen-metal compounds, compositions of such antioxidant cyclic salen-metal compounds having superoxide activity, catalase activity and/or peroxidase activity and methods of using such antioxidant cyclic salen-metal compositions to treat or prevent a disease associated with cell or tissue damage produced by free radicals, such as superoxide.
    Type: Application
    Filed: May 27, 2003
    Publication date: March 25, 2004
    Inventors: Bernard Malfroy-Camine, Susan Doctrow
  • Cyclic salen-metal compounds: reactive oxygen species scavengers useful as antioxidants in the treatment and prevention of diseases
    Patent number: 6589948
    Abstract: This invention provides antioxidant cyclic salen-metal compounds, compositions of such antioxidant cyclic salen-metal compounds having superoxide activity, catalase activity and/or peroxidase activity and methods of using such antioxidant cyclic salen-metal compositions to treat or prevent a disease associated with cell or tissue damage produced by free radicals, such as superoxide.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: July 8, 2003
    Assignee: Eukarion, Inc.
    Inventors: Bernard Malfroy-Camine, Susan Doctrow