Patents by Inventor Susan E. Witko

Susan E. Witko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR PACKAGING PROPAGATION-DEFECTIVE VESICULAR STOMATITIS VIRUS VECTORS
    Publication number: 20090175900
    Abstract: A method of producing propagation-defective Vesicular Stomatitis Virus (VSV) in a cell culture is provided. The method involves introducing a plasmid vector encoding an optimized VSV G gene into a cell; expressing VSV G protein from the optimized VSV G gene; and introducing a propagation-defective VSV into the cell expressing the VSV G protein encoded by the optimized VSV G gene. The method further includes growing the cells in culture; and recovering the propagation-defective VSV from the culture.
    Type: Application
    Filed: December 16, 2008
    Publication date: July 9, 2009
    Applicant: Wyeth
    Inventors: Christopher L. Parks, Susan E. Witko, Maninder K. Sidhu, J. Erik Johnson, Roger Michael Hendry
  • METHODS FOR PACKAGING PROPAGATION-DEFECTIVE VESICULAR STOMATITIS VIRUS VECTORS USING A STABLE CELL LINE THAT EXPRESSES G PROTEIN
    Publication number: 20090162321
    Abstract: A method of producing propagation-defective Vesicular Stomatitis Virus (VSV) is provided. The method involves providing a cell that includes an optimized VSV G gene, wherein expression of VSV G protein from the optimized VSV G gene is inducible; and inducing the cell to express VSV G protein from the optimized VSV G gene. The method also involves infecting the induced cell with an attenuated VSV; growing the infected cells in culture; and recovering attenuated VSV from the culture.
    Type: Application
    Filed: December 16, 2008
    Publication date: June 25, 2009
    Applicant: Wyeth
    Inventors: Christopher L. Parks, Susan E. Witko, Maninder K. Sidhu, J. Erik Johnson, Roger Michael Hendry