Patents by Inventor Susan F. Law

Susan F. Law has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Signal mediator protein that induces cellular morphological alterations
    Patent number: 6124434
    Abstract: An isolated nucleic acid molecule is provided which encodes a mammalian signal mediator protein involved in regulation of cellular morphological alterations. The encoded protein comprises an amino-terminal SH3 domain, an Internal domain containing several SH2 binding motifs, and a carboxy-terminal effector domain that can induce pseudohyphal budding in yeast. The invention also provides the novel signal mediator protein, and antibodies thereto. These biological molecules are useful as research tools and as diagnostic and therapeutic agents for the identification, detection and regulation of complex signaling events leading to morphological, potentially neoplastic, cellular changes.
    Type: Grant
    Filed: November 19, 1998
    Date of Patent: September 26, 2000
    Assignee: Fox Chase Cancer Center
    Inventors: Erica A. Golemis, Susan F. Law, Joanne Estojak
  • Antibodies immunologically specific for a signal mediator protein that induces cellular morphological alterations
    Patent number: 6100384
    Abstract: An isolated nucleic acid molecule is provided which encodes a mammalian signal mediator protein involved in regulation of cellular morphological alterations. The encoded protein comprises an amino-terminal SH3 domain, an internal domain containing several SH2 binding motifs, and a carboxy-terminal effector domain that can induce pseudohyphal budding in yeast. The invention also provides the novel signal mediator protein, and antibodies thereto. These biological molecules are useful as research tools and as diagnostic and therapeutic agents for the identification, detection and regulation of complex signaling events leading to morphological, potentially neoplastic, cellular changes.
    Type: Grant
    Filed: November 12, 1997
    Date of Patent: August 8, 2000
    Assignee: Fox Chase Cancer Center
    Inventors: Erica A. Golemis, Susan F. Law, Joanne Estojak
  • Nucleic acid encoding a signal mediator protein that induces cellular morphological alterations
    Patent number: 5716782
    Abstract: An isolated nucleic acid molecule is provided which encodes a mammalian signal mediator protein involved in regulation of cellular morphological alterations. The encoded protein comprises an amino-terminal SH3 domain, an internal domain containing several SH2 binding motifs, and a carboxy-terminal effector domain that can induce pseudohyphal budding in yeast. The invention also provides the novel signal mediator protein, and antibodies thereto. These biological molecules are useful as research tools and as diagnostic and therapeutic agents for the identification, detection and regulation of complex signaling events leading to morphological, potentially neoplastic, cellular changes.
    Type: Grant
    Filed: June 30, 1995
    Date of Patent: February 10, 1998
    Assignee: Fox Chase Cancer Center
    Inventors: Erica A. Golemis, Susan F. Law, Joanne Estojak