Patents by Inventor Susan Foley

Susan Foley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Linker peptides and polypeptides comprising same
    Patent number: 9409950
    Abstract: The invention is based, at least in part, on the finding that linker peptides which lack the amino acid sequence GSG reduce or eliminate the addition of posttranslational modifications to the polypeptides which comprise them. More specifically, the novel linker peptides disclosed herein reduce the ability of enzymes to link carbohydrate adducts to polypeptides comprising these linker peptides, e.g., reduce the ability of xylosyltransferase to link xylose to polypeptides. These novel linker peptides, molecules comprising same, and methods of their use are described.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: August 9, 2016
    Assignee: Biogen MA Inc.
    Inventors: Brian Robert Miller, Scott Glaser, Justin Caravella, Susan Foley, Xiaoping Hronowski, Tigran Aivazian
  • LINKER PEPTIDES AND POLYPEPTIDES COMPRISING SAME
    Publication number: 20140079701
    Abstract: The invention is based, at least in part, on the finding that linker peptides which lack the amino acid sequence GSG reduce or eliminate the addition of posttranslational modifications to the polypeptides which comprise them. More specifically, the novel linker peptides disclosed herein reduce the ability of enzymes to link carbohydrate adducts to polypeptides comprising these linker peptides, e.g., reduce the ability of xylosyltransferase to link xylose to polypeptides. These novel linker peptides, molecules comprising same, and methods of their use are described.
    Type: Application
    Filed: December 22, 2011
    Publication date: March 20, 2014
    Applicant: BIOGEN IDEC MA INC.
    Inventors: Brian Robert Miller, Scott Glaser, Justin Caravella, Susan Foley, Xiaoping Hronoeski, Tigran Dikran Alvazian
  • Cripto mutant and uses thereof
    Patent number: 7604931
    Abstract: The present invention is based on the discovery that CRIPTO mutants each comprising at least one amino acid substitution from a CRIPTO polypeptide demonstrate tumor blocking activity.
    Type: Grant
    Filed: March 17, 2003
    Date of Patent: October 20, 2009
    Assignee: Biogen Idec MA Inc.
    Inventors: Kevin P. Williams, Susan Foley, Susan Schiffer, Bruno Domon, Michele Sanicola-Nadel
  • Cripto mutant and uses thereof
    Publication number: 20030232755
    Abstract: The present invention is based on the discovery that CRIPTO mutants each comprising at least one amino acid substitution from a CRIPTO polypeptide demonstrate tumor blocking activity.
    Type: Application
    Filed: March 17, 2003
    Publication date: December 18, 2003
    Applicant: BIOGEN, INC.
    Inventors: Kevin P. Williams, Susan Foley, Susan Schiffer, Bruno Domon, Michele Sanicola-Nadel