Patents by Inventor Susan Harran

Susan Harran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diazonamide analogs
    Patent number: 8846734
    Abstract: Diazonamide analogs having anti-mitotic activity, useful for the treatment of cancer and other proliferative disorders, and related pharmaceutical compositions are provided.
    Type: Grant
    Filed: November 25, 2013
    Date of Patent: September 30, 2014
    Assignee: Joyant Pharmaceuticals, Inc.
    Inventors: Qi Wei, Ming Zhou, Xiaoming Xu, Charles Caldwell, Susan Harran, Lai Wang
  • Diazonamide Analogs
    Publication number: 20140100193
    Abstract: Diazonamide analogs having anti-mitotic activity, useful for the treatment of cancer and other proliferative disorders, and related pharmaceutical compositions are provided.
    Type: Application
    Filed: November 25, 2013
    Publication date: April 10, 2014
    Applicant: Joyant Pharmaceuticals, Inc.
    Inventors: Qi Wei, Ming Zhou, Xiaoming Xu, Charles Caldwell, Susan Harran, Lai Wang
  • Dimeric Smac Mimetics
    Publication number: 20130344026
    Abstract: The invention provides small molecule mimics of the Smac peptide that are dimers or dimer-like compounds having two binding domains connected by a linker. These compounds are useful to promote apoptosis. The invention includes pharmaceutical compositions comprising such compounds and methods to use them to treat conditions including cancer and autoimmune disorders.
    Type: Application
    Filed: August 22, 2013
    Publication date: December 26, 2013
    Inventors: Haizhou Sun, Xiaoming Xu, Ming Zhou, Susan Harran, Gunnar James Hanson, Lai Wang
  • Diazonamide analogs
    Patent number: 8592469
    Abstract: Diazonamide analogs having anti-mitotic activity, useful for the treatment of cancer and other proliferative disorders, and related pharmaceutical compositions are provided.
    Type: Grant
    Filed: April 15, 2012
    Date of Patent: November 26, 2013
    Assignee: Joyant Pharmaceuticals, Inc.
    Inventors: Qi Wei, Ming Zhou, Xiaoming Xu, Charles Caldwell, Susan Harran, Lai Wang
  • Small molecule apoptosis promoters
    Patent number: 8586542
    Abstract: The invention provides small molecule mimics of the Smac peptide that are dimer- or dimer-like compounds having two amide-containing domains connected by a linker. These compounds are useful to promote apoptosis. The invention includes pharmaceutical compositions comprising such compounds and methods to use them to treat conditions including cancer and autoimmune disorders.
    Type: Grant
    Filed: June 28, 2012
    Date of Patent: November 19, 2013
    Assignee: Joyant Pharmaceuticals, Inc.
    Inventors: Gunnar J. Hanson, David Thomas, Nizal Chandrakumar, Susan Harran
  • SMALL MOLECULE APOPTOSIS PROMOTERS
    Publication number: 20130281385
    Abstract: The invention provides small molecule mimics of the Smac peptide that are dimer- or dimer-like compounds having two amide-containing domains connected by a linker. These compounds are useful to promote apoptosis. The invention includes pharmaceutical compositions comprising such compounds and methods to use them to treat conditions including cancer and autoimmune disorders.
    Type: Application
    Filed: June 28, 2012
    Publication date: October 24, 2013
    Inventors: Gunnar J. Hanson, Davis Thomas, Nizal Chandrakumar, Susan Harran
  • Dimeric Smac mimetics
    Patent number: 8551955
    Abstract: The invention provides small molecule mimics of the Smac peptide that are dimers or dimer-like compounds having two binding domains connected by a linker. These compounds are useful to promote apoptosis. The invention includes pharmaceutical compositions comprising such compounds and methods to use them to treat conditions including cancer and autoimmune disorders.
    Type: Grant
    Filed: October 28, 2010
    Date of Patent: October 8, 2013
    Assignee: Joyant Pharmaceuticals, Inc.
    Inventors: Haizhou Sun, Xiaoming Xu, Ming Zhou, Susan Harran, Gunnar James Hanson, Lai Wang
  • Indoline anti-cancer agents
    Patent number: 8334311
    Abstract: Indoline compounds having anti-mitotic activity, useful for the treatment of cancer and other proliferative disorders are provided.
    Type: Grant
    Filed: July 25, 2011
    Date of Patent: December 18, 2012
    Assignee: Joyant Pharmaceuticals, Inc.
    Inventors: Gunnar James Hanson, Qi Wei, Charles Caldwell, Ming Zhou, Lai Wang, Susan Harran
  • Methods for preparing diazonamides
    Patent number: 8299268
    Abstract: This invention relates to novel macrocyclic lactams intermediates useful for the preparation of diazonamide analogs. This invention also relates to a novel electrochemical oxidative cyclization for the preparation of such macrocyclic lactams, and their further elucidation to provide diazonamide analogs.
    Type: Grant
    Filed: July 19, 2011
    Date of Patent: October 30, 2012
    Assignees: Board of Regents, The University of Texas System, Joyant Pharmaceuticals, Inc.
    Inventors: Gunnar Hanson, Charles Caldwell, Patrick G. Harran, Susan Harran, Qi Wei, Ming Zhou
  • Diazonamide Analogs
    Publication number: 20120270841
    Abstract: Diazonamide analogs having anti-mitotic activity, useful for the treatment of cancer and other proliferative disorders, and related pharmaceutical compositions are provided.
    Type: Application
    Filed: April 15, 2012
    Publication date: October 25, 2012
    Inventors: Qi Wei, Ming Zhou, Xiaoming Xu, Charles Caldwell, Susan Harran, Lai Wang
  • Indoline Anti-Cancer Agents
    Publication number: 20120264763
    Abstract: Indoline compounds having anti-mitotic activity, useful for the treatment of cancer and other proliferative disorders are provided.
    Type: Application
    Filed: July 25, 2011
    Publication date: October 18, 2012
    Inventors: Gunnar James Hanson, Qi Wei, Charles Caldwell, Ming Zhou, Lai Wang, Susan Harran
  • Methods for Preparing Diazonamides
    Publication number: 20120190862
    Abstract: This invention relates to novel macrocyclic lactams intermediates useful for the preparation of diazonamide analogs. This invention also relates to a novel electrochemical oxidative cyclization for the preparation of such macrocyclic lactams, and their further elucidation to provide diazonamide analogs.
    Type: Application
    Filed: July 19, 2011
    Publication date: July 26, 2012
    Inventors: Gunnar HANSON, Charles CALDWELL, Patrick G. HARRAN, Susan HARRAN, Qi WEI, Ming ZHOU
  • Small molecule apoptosis promoters
    Patent number: 8222291
    Abstract: The invention provides small molecule mimics of the Smac peptide that are dimer- or dimer-like compounds having two amide-containing domains connected by a linker. These compounds are useful to promote apoptosis. The invention includes pharmaceutical compositions comprising such compounds and methods to use them to treat conditions including cancer and autoimmune disorders.
    Type: Grant
    Filed: October 4, 2010
    Date of Patent: July 17, 2012
    Assignee: Joyant Pharmaceuticals, Inc.
    Inventors: Gunnar J. Hanson, David Thomas, Nizal Chandrakumar, Susan Harran
  • Small molecule apoptosis promoters
    Publication number: 20120082640
    Abstract: The invention provides small molecule mimics of the Smac peptide that are dimer- or dimer-like compounds having two amide-containing domains connected by a linker. These compounds are useful to promote apoptosis. The invention includes pharmaceutical compositions comprising such compounds and methods to use them to treat conditions including cancer and autoimmune disorders.
    Type: Application
    Filed: October 4, 2010
    Publication date: April 5, 2012
    Inventors: Gunnar J. Hanson, David Thomas, Nizal Chandrakumar, Susan Harran
  • Dimeric Smac Mimetics
    Publication number: 20110195043
    Abstract: The invention provides small molecule mimics of the Smac peptide that are dimers or dimer-like compounds having two binding domains connected by a linker These compounds are useful to promote apoptosis. The invention includes pharmaceutical compositions comprising such compounds and methods to use them to treat conditions including cancer and autoimmune disorders.
    Type: Application
    Filed: October 28, 2010
    Publication date: August 11, 2011
    Inventors: Haizhou Sun, Xiaoming Xu, Ming Zhou, Susan Harran, Gunnar James Hanson, Lai Wang
  • Indoline anti-cancer agents
    Patent number: 7989482
    Abstract: Indoline compounds having anti-mitotic activity, useful for the treatment of cancer and other proliferative disorders are provided.
    Type: Grant
    Filed: April 29, 2009
    Date of Patent: August 2, 2011
    Assignee: Joyant Pharmaceuticals, Inc.
    Inventors: Gunnar James Hanson, Qi Wei, Charles Caldwell, Ming Zhou, Lai Wang, Susan Harran
  • Methods for preparing diazonamides
    Patent number: 7982051
    Abstract: This invention relates to novel macrocyclic lactams intermediates useful for the preparation of diazonamide analogs. This invention also relates to a novel electrochemical oxidative cyclization for the preparation of such macrocyclic lactams, and their further elucidation to provide diazonamide analogs.
    Type: Grant
    Filed: October 3, 2010
    Date of Patent: July 19, 2011
    Assignees: Board of Regents, The University of Texas System, Joyant Pharmaceuticals, Inc.
    Inventors: Gunnar Hanson, Charles Caldwell, Patrick G. Harran, Susan Harran, Qi Wei, Ming Zhou
  • Methods for Preparing Diazonamides
    Publication number: 20110021784
    Abstract: This invention relates to novel macrocyclic lactams intermediates useful for the preparation of diazonamide analogs. This invention also relates to a novel electrochemical oxidative cyclization for the preparation of such macrocyclic lactams, and their further elucidation to provide diazonamide analogs.
    Type: Application
    Filed: October 3, 2010
    Publication date: January 27, 2011
    Inventors: Gunnar Hanson, Charles Caldwell, Patrick G. Harran, Susan Harran, Qi Wei, Ming Zhou
  • Methods for preparing diazonamides
    Patent number: 7851620
    Abstract: This invention relates to novel macrocyclic lactams intermediates useful for the preparation of diazonamide analogs. This invention also relates to a novel electrochemical oxidative cyclization for the preparation of such macrocyclic lactams, and their further elucidation to provide diazonamide analogs.
    Type: Grant
    Filed: June 6, 2008
    Date of Patent: December 14, 2010
    Assignees: Board of Regents, The University of Texas System, Joyant Pharmaceuticals, Inc.
    Inventors: Gunnar Hanson, Charles Caldwell, Patrick G. Harran, Susan Harran, Qi Wei, Ming Zhou
  • Dimeric pyrrolidine amide-containing small molecule apoptosis promoters
    Patent number: 7807699
    Abstract: The invention provides small molecule mimics of the Smac peptide that are dimer- or dimer-like compounds having two amide-containing domains connected by a linker. These compounds are useful to promote apoptosis. The invention includes pharmaceutical compositions comprising such compounds and methods to use them to treat conditions including cancer and autoimmune disorders.
    Type: Grant
    Filed: March 21, 2007
    Date of Patent: October 5, 2010
    Assignee: Joyant Pharmaceuticals, Inc.
    Inventors: Gunnar J. Hanson, David Thomas, Nizal Chandrakumar, Susan Harran