Patents by Inventor Susan Hockfield

Susan Hockfield has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRIMARY CENTRAL NERVOUS SYSTEM TUMOR SPECIFIC BEHAB ISOFORMS
    Publication number: 20090117595
    Abstract: The present invention comprises compositions and methods related to a glycosylation-variant BEHAB protein, poly-sialyated full-length BEHAB, and methods of use thereof.
    Type: Application
    Filed: January 14, 2005
    Publication date: May 7, 2009
    Applicant: Yale University
    Inventors: Susan Hockfield, Russell T. Matthews, Mariano S. Viapiano
  • Primary central nervous system tumor specific BEHAB isoforms
    Publication number: 20060166290
    Abstract: The present invention comprises compositions and methods related to a glycosylation-variant BEHAB polypeptide, a poly-sialyated BEHAB polypeptide, and methods of use thereof.
    Type: Application
    Filed: January 14, 2005
    Publication date: July 27, 2006
    Inventors: Susan Hockfield, Russell Matthews, Mariano Viapiano
  • Inhibition of BEHAB cleavage and primary central nervous system (CNS) tumors
    Patent number: 6884619
    Abstract: The present invention relates to primary CNS tumors and provides useful compositions and methods for reducing tumor volume and increasing the length of survival in mammals with primary CNS tumors, thereby providing a treatment for primary CNS tumors. The invention also relates to methods of identifying compounds for reducing tumor volume and increasing animal survival, which therefore relate to treating primary CNS tumors.
    Type: Grant
    Filed: July 16, 2002
    Date of Patent: April 26, 2005
    Assignee: Yale University
    Inventors: Susan Hockfield, Russell T. Matthews
  • Compositions, methods and kits relating to behab and primary CNS tumors
    Publication number: 20030224976
    Abstract: The present invention relates to primary CNS tumors and provides useful compositions and methods for reducing tumor volume and increasing the length of survival in mammals with primary CNS tumors, thereby providing a treatment for primary CNS tumors. The invention also relates to methods of identifying compounds for reducing tumor volume and increasing animal survival, which therefore relate to treating primary CNS tumors. The invention also relates to methods of detecting and diagnosing a tumor.
    Type: Application
    Filed: June 2, 2003
    Publication date: December 4, 2003
    Applicant: Yale University
    Inventors: Susan Hockfield, Russell T. Matthews, Mariano S. Viapiano
  • Inhibition of BEHAB cleavage and primary central nervous system (CNS) tumors
    Publication number: 20030068661
    Abstract: The present invention relates to primary CNS tumors and provides useful compositions and methods for reducing tumor volume and increasing the length of survival in mammals with primary CNS tumors, thereby providing a treatment for primary CNS tumors. The invention also relates to methods of identifying compounds for reducing tumor volume and increasing animal survival, which therefore relate to treating primary CNS tumors.
    Type: Application
    Filed: July 16, 2002
    Publication date: April 10, 2003
    Applicant: Yale University
    Inventors: Susan Hockfield, Russell T. Matthews
  • DNA encoding BEHAB, a brain hyaluronan-binding protein, and recombinant expression systems for production of BEHAB polypeptides
    Patent number: 5635370
    Abstract: A gene encoding mammalian brain enriched hyaluronan binding (BEHAB) protein is isolated and characterized from brain tissue and found to have a high degree of sequence homology to members of the proteoglycan tandem repeat family of hyaluronan binding proteins. Unlike other members of the family, however, the expression of the gene is restricted to the central nervous system. BEHAB is expressed in markedly increased levels in human glioma tissue, so that the polypeptide can be used as a marker for diagnostic purposes.
    Type: Grant
    Filed: April 8, 1994
    Date of Patent: June 3, 1997
    Assignee: Yale University
    Inventors: Susan Hockfield, Diane M. Jaworski