Patents by Inventor Susan J. deSolms

Susan J. deSolms has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted hexahydroarylquinolizines
    Patent number: 4916223
    Abstract: Certain substituted hexahydroarylquinolizines and pharmaceutically acceptable salts thereof are peripherally selective .alpha..sub.2 -adrenoceptor antagonists. The compounds are adapted to be employed for the treatment of certain pathological disorders such as hypertension, diabetes, disorders involving platelet aggregation and the like without side effects attributable to effect on the central nervous system.
    Type: Grant
    Filed: February 6, 1989
    Date of Patent: April 10, 1990
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Joel R. Huff, Susan J. DeSolms, Joseph P. Vacca, Jonathan M. Wiggins, Steven D. Young
  • Substituted hexahydroarylquinolizines
    Patent number: 4831035
    Abstract: Certain substituted hexahydroarylquinolizines and pharmaceutically acceptable salts thereof are peripherally selective .alpha..sub.2 -adrenoceptor antagonists. The compounds are adapted to be employed for the treatment of certain pathological disorders such as hypertension, diabetes, disorders involving platelet aggregation and the like without side effects attributable to effect on the central nervous system.
    Type: Grant
    Filed: July 27, 1987
    Date of Patent: May 16, 1989
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Joel R. Huff, Susan J. deSolms, Joseph P. Vacca, Jonathan M. Wiggins, Steven D. Young
  • Heterocyclic substituted pyrazinoylguanidines
    Patent number: 4246406
    Abstract: The case involves novel heterocyclic substituted pyrazinoylguanidines and a process for preparing same. The heterocyclic pyrazinoylguanidines are eukalemic agents possessing diuretic and natriuretic properties.
    Type: Grant
    Filed: March 27, 1979
    Date of Patent: January 20, 1981
    Assignee: Merck & Co., Inc.
    Inventors: Edward J. Cragoe, Jr., Otto W. Woltersdorf, Jr., Susan J. DeSolms
  • Novel pyrazinecarboxamides and processes for preparing same
    Patent number: 4224447
    Abstract: The case involves novel pyrazinecarboxamide compounds and processes for preparing same. The pyrazinecarboxamides are eukalemic agents possessing diuretic and natriuretic properties.
    Type: Grant
    Filed: March 27, 1979
    Date of Patent: September 23, 1980
    Assignee: Merck & Co., Inc.
    Inventors: Otto W. Woltersdorf, Jr., Susan J. deSolms
  • 6-Substituted amiloride derivatives
    Patent number: 4196292
    Abstract: N-amidino-3,5-diamino-6-substituted-2-pyrazinecarboxamides and a process for their synthesis.
    Type: Grant
    Filed: June 29, 1977
    Date of Patent: April 1, 1980
    Assignee: Merck & Co., Inc.
    Inventors: Otto W. Woltersdorf, Jr., Susan J. deSolms, Edward J. Cragoe, Jr.