Patents by Inventor Susan J. Knox

Susan J. Knox has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING CANCER WITH ANDROGEN DEPRIVATION THERAPY IN COMBINATION WITH AN INHIBITOR OF THE SP1 TRANSCRIPTION FACTOR
    Publication number: 20210046106
    Abstract: Methods for treating cancer using combination therapy with an inhibitor of the Sp1 transcription factor and radiation therapy are disclosed.
    Type: Application
    Filed: May 26, 2020
    Publication date: February 18, 2021
    Inventors: Susan J. Knox, Donna M. Peehl, Junqiang Tian
  • Methods for treating a neoplastic disease in a subject using inorganic selenium-containing compounds
    Patent number: 9248149
    Abstract: The invention features methods and selenium-containing compositions for treating a neoplastic disease in a subject. In particular, the invention features methods for enhancing sensitivity of a tumor to cancer therapy by treating the tumor with an inorganic selenium-containing (iSe) compound and with a cancer therapy, particularly a cancer therapy that also affects the cellular redox status of a tumor cell (e.g., radiation).
    Type: Grant
    Filed: November 25, 2014
    Date of Patent: February 2, 2016
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Susan J. Knox, Bryan Husbeck
  • Methods for Treating a Neoplastic Disease in a Subject Using Inorganic Selenium-Containing Compounds
    Publication number: 20150147413
    Abstract: The invention features methods and selenium-containing compositions for treating a neoplastic disease in a subject. In particular, the invention features methods for enhancing sensitivity of a tumor to cancer therapy by treating the tumor with an inorganic selenium-containing (iSe) compound and with a cancer therapy, particularly a cancer therapy that also affects the cellular redox status of a tumor cell (e.g., radiation).
    Type: Application
    Filed: November 25, 2014
    Publication date: May 28, 2015
    Inventors: SUSAN J. KNOX, BRYAN HUSBECK
  • Methods for treating a neoplastic disease in a subject using inorganic selenium-containing compounds
    Patent number: 8932649
    Abstract: The invention features methods and selenium-containing compositions for treating a neoplastic disease in a subject. In particular, the invention features methods for enhancing sensitivity of a tumor to cancer therapy by treating the tumor with an inorganic selenium-containing (iSe) compound and with a cancer therapy, particularly a cancer therapy that also affects the cellular redox status of a tumor cell (e.g., radiation).
    Type: Grant
    Filed: November 12, 2004
    Date of Patent: January 13, 2015
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Susan J. Knox, Bryan Husbeck
  • X-NITRO COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF AND USES THEREOF
    Publication number: 20090291935
    Abstract: The present invention provides X-nitro compound, pharmaceutical compositions of X-nitro compounds and methods of using X-nitro compounds and/or pharmaceutical compositions thereof to treat or prevent diseases or disorders characterized by abnormal cell proliferation, such as cancer, inflammation, cardiovascular disease and autoimmune disease.
    Type: Application
    Filed: April 23, 2009
    Publication date: November 26, 2009
    Applicant: RadioRx, Inc.
    Inventors: Mark D. BEDNARSKI, Lynn M. Oehler, Andrew C. Haaland, Susan J. Knox
  • X-nitro compounds, pharmaceutical compositions thereof and uses thereof
    Publication number: 20040167212
    Abstract: The present invention provides X-nitro compound, pharmaceutical compositions of X-nitro compounds and methods of using X-nitro compounds and/or pharmaceutical compositions thereof to treat or prevent diseases or disorders characterized by abnormal cell proliferation, such as cancer, inflammation, cardiovascular disease and autoimmune disease.
    Type: Application
    Filed: October 7, 2003
    Publication date: August 26, 2004
    Inventors: Mark D. Bednarski, Andrew C. Haaland, Susan J. Knox
  • Methods for modulating effects of radiation in a subject
    Publication number: 20040132645
    Abstract: The invention features methods and compositions for modulating the effects of radiation in a subject. In one embodiment, the invention features methods for enhancing radiosensitivity of a tumor in an anemic subject by administration of erythropoietin (EPO), particularly a hyperglycosylated EPO isoform such as ARANESP™. In general, the invention provides methods for potentiating the effects of radiation therapy in a subject without the need for correction or complete correction of anemia in the subject prior to initiation of radiation therapy. The invention further provides for improved recovery from bone marrow suppression (including non erythroid cell types) and improved overall health of the subject. In another embodiment the invention features methods for treatment of an irradiated subject by accelerating recovery of bone marrow cells (including non-erythroid cell types) in an irradiated subject or mitigating the effects of radiation upon such cells.
    Type: Application
    Filed: January 3, 2003
    Publication date: July 8, 2004
    Inventors: Susan J. Knox, Shoucheng Ning