Patents by Inventor Susan K. Heimbecher

Susan K. Heimbecher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Posaconazole intravenous solution formulations stabilized by substituted ?-cyclodextrin
    Patent number: 9358297
    Abstract: The present invention relates to aqueous solutions useful as pharmaceutical compositions of posaconazole for intravenous administration. These compositions include a solubilizing agent, such as a modified ?-cyclodextrin in an acidified solution, which can also include a chelating agent such as disodium edetate (EDTA). In clinical trials, a 200 mg posaconazole dose of the selected composition was found to achieve acceptable pharmacokinetic properties.
    Type: Grant
    Filed: March 25, 2015
    Date of Patent: June 7, 2016
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Susan K. Heimbecher, David Monteith, James D. Pipkin
  • POSACONAZOLE INTRAVENOUS SOLUTION FORMULATIONS STABILIZED BY SUBSTITUTED BETA-CYCLODEXTRIN
    Publication number: 20150265715
    Abstract: The present invention relates to aqueous solutions useful as pharmaceutical compositions of posaconazole for intravenous administration. These compositions include a solubilizing agent, such as a modified ?-cyclodextrin in an acidified solution, which can also include a chelating agent such as disodium edetate (EDTA). In clinical trials, a 200 mg posaconazole dose of the selected composition was found to achieve acceptable pharmacokinetic properties.
    Type: Application
    Filed: March 25, 2015
    Publication date: September 24, 2015
    Applicant: MERCK SHARP & DOHME CORP.
    Inventors: Susan K. Heimbecher, David Monteith, James D. Pipkin
  • Posaconazole intravenous solution formulations stabilized by substituted ?-cyclodextrin
    Patent number: 9023790
    Abstract: The present invention relates to aqueous solutions useful as pharmaceutical compositions of posaconazole for intravenous administration. These compositions include a solubilizing agent, such as a modified ?-cyclodextrin in an acidified solution, which can also include a chelating agent such as disodium edetate (EDTA). In clinical trials, a 200 mg posaconazole dose of the selected composition was found to achieve acceptable pharmacokinetic properties.
    Type: Grant
    Filed: June 24, 2011
    Date of Patent: May 5, 2015
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Susan K. Heimbecher, David Monteith, James D. Pipkin
  • POSACONAZOLE INTRAVENOUS SOLUTION FORMULATIONS STABILIZED BY SUBSTITUTED BETA-CYCLODEXTRIN
    Publication number: 20130096053
    Abstract: The present invention relates to aqueous solutions useful as pharmaceutical compositions of posaconazole for intravenous administration. These compositions include a solubilizing agent, such as a modified ?-cyclodextrin in an acidified solution, which can also include a chelating agent such as disodium edetate (EDTA). In clinical trials, a 200 mg posaconazole dose of the selected composition was found to achieve acceptable pharmacokinetic properties.
    Type: Application
    Filed: June 24, 2011
    Publication date: April 18, 2013
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Susan K. Heimbecher, David Monteith
  • PHARMACEUTICAL COMPOSITIONS
    Publication number: 20110207740
    Abstract: Disclosed are useful pharmaceutical compositions.
    Type: Application
    Filed: April 4, 2011
    Publication date: August 25, 2011
    Inventors: Susan K. Heimbecher, Jim H. Kou, Irina Kazakevich
  • PHARMACEUTICAL COMPOSITIONS
    Publication number: 20080293734
    Abstract: Disclosed are useful pharmaceutical compositions.
    Type: Application
    Filed: August 5, 2008
    Publication date: November 27, 2008
    Inventors: Susan K. Heimbecher, Jim H. Kou, Irina Kazakevich
  • Ribavirin syrup formulations
    Patent number: 6790837
    Abstract: A liquid formulation comprising ribavirin having a longer shelf life and improved taste is disclosed.
    Type: Grant
    Filed: October 31, 2002
    Date of Patent: September 14, 2004
    Assignee: Schering Corporation
    Inventors: Susan K. Heimbecher, Joel A. Sequeira
  • Ribavirin syrup formulations
    Publication number: 20030087844
    Abstract: A liquid formulation comprising ribavirin having a longer shelf life and improved taste is disclosed.
    Type: Application
    Filed: October 31, 2002
    Publication date: May 8, 2003
    Applicant: SCHERING CORPORATION
    Inventors: Susan K. Heimbecher, Joel A. Sequeira