Patents by Inventor Susan K. Keesee

Susan K. Keesee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6803189
    Abstract: The invention provides a wide range of methods and compositions for detecting and treating cervical cancer in an individual. Specifically, the invention provides target cervical cancer-associated proteins, which permit a rapid detection, preferably before metastases occur, of cervical cancer. The target cervical cancer-associated protein, may be detected, for example, by reacting the sample with a labeled binding moiety, for example, a labeled antibody capable of binding specifically to the protein. The invention also provides kits useful in the detection of cervical cancer in an individual. In addition, the invention provides methods utilizing the cervical cancer-associated proteins either as targets for treating cervical cancer or as indicators for monitoring of the efficacy of such a treatment.
    Type: Grant
    Filed: May 17, 1999
    Date of Patent: October 12, 2004
    Assignee: Matritech, Inc.
    Inventors: Susan K. Keesee, Robert Obar, Ying-Jye Wu
  • Publication number: 20030157482
    Abstract: The invention provides a wide range of methods and compositions for detecting and treating cervical cancer in an individual. Specifically, the invention provides target cervical cancer-associated proteins, which permit a rapid detection, preferably before metastases occur, of cervical cancer. The target cervical cancer-associated protein, may be detected, for example, by reacting the sample with a labeled binding moiety, for example, a labeled antibody capable of binding specifically to the protein. The invention also provides kits useful in the detection of cervical cancer in an individual. In addition, the invention provides methods utilizing the cervical cancer-associated proteins either as targets for treating cervical cancer or as indicators for monitoring of the efficacy of such a treatment.
    Type: Application
    Filed: May 17, 1999
    Publication date: August 21, 2003
    Inventors: SUSAN K. KEESEE, ROBERT OBAR, YING-JYE WU
  • Patent number: 6218131
    Abstract: Disclosed are proteins indicative of breast cancer and of other cancers, and methods for their detection. Methods of the invention provide an improvement in cancer detection assays, especially in breast cancer detection assays.
    Type: Grant
    Filed: October 6, 1997
    Date of Patent: April 17, 2001
    Assignee: Matritech, Inc.
    Inventors: Susan K. Keesee, Robert Obar, Ying-Jye Wu
  • Patent number: 6027905
    Abstract: The invention provides a wide range of methods and compositions for detecting and treating cervical cancer in an individual. Specifically, the invention provides target cervical cancer-associated proteins, which permit a rapid detection, preferably before metastases occur, of cervical cancer. The target cervical cancer-associated protein, may be detected, for example, by reacting the sample with a labeled binding moiety, for example, a labeled antibody capable of binding specifically to the protein. The invention also provides kits useful in the detection of cervical cancer in an individual. In addition, the invention provides methods utilizing the cervical cancer-associated proteins either as targets for treating cervical cancer or as indicators for monitoring of the efficacy of such a treatment.
    Type: Grant
    Filed: December 11, 1997
    Date of Patent: February 22, 2000
    Assignee: Matritech, Inc.
    Inventors: Susan K. Keesee, Robert Obar, Ying-Jye Wu
  • Patent number: 5914238
    Abstract: Provided are materials and methods for early diagnosis of breast cancer by detection of breast cancer-associated proteins.
    Type: Grant
    Filed: June 5, 1996
    Date of Patent: June 22, 1999
    Assignee: Matritech, Inc.
    Inventors: Susan K. Keesee, Robert Obar, Ying-Jye Wu
  • Patent number: 5858683
    Abstract: The invention provides a wide range of methods and compositions for detecting and treating cervical cancer in an individual. Specifically, the invention provides target cervical cancer-associated proteins, which permit a rapid detection, preferably before metastases occur, of cervical cancer. The target cervical cancer-associated protein, may be detected, for example, by reacting the sample with a labeled binding moiety, for example, a labeled antibody capable of binding specifically to the protein. The invention also provides kits useful in the detection of cervical cancer in an individual. In addition, the invention provides methods utilizing the cervical cancer-associated proteins either as targets for treating cervical cancer or as indicators for monitoring of the efficacy of such a treatment.
    Type: Grant
    Filed: August 30, 1996
    Date of Patent: January 12, 1999
    Assignee: Matritech, Inc.
    Inventors: Susan K. Keesee, Robert Obar, Ying-Jye Wu
  • Patent number: 5830677
    Abstract: The invention provides methods and compositions for identifying colon cancers in an individual. In one embodiment of the invention, a colon adenocarcinoma-associated protein may be detected in a tissue or body fluid sample of an individual, to provide an indication of the presence of an adenocarcinoma of the colon in the individual. The target adenocarcinoma-associated protein, may be detected, e.g., by reacting the sample with a labeled binding moiety, such as a labeled antibody, capable of specifically binding the protein. In another embodiment, the protein may be detected by isolating one or more colon adenocarcinoma-associated proteins from the sample, separating the proteins by two dimensional gel electrophoresis, and comparing the gel electrophoresis pattern with a standard. The invention provides a wide range of assay methods and compositions which may be used for detecting colon tumors in an individual rapidly and reproducibly, optimally at early stages of the disease.
    Type: Grant
    Filed: May 23, 1995
    Date of Patent: November 3, 1998
    Assignee: Matritech, Inc.
    Inventors: Ying-Jye Wu, Susan K. Keesee
  • Patent number: 5547928
    Abstract: The invention provides methods and compositions for identifying colon cancers in an individual. In one embodiment of the invention, a colon adenocarcinoma-associated protein may be detected in a tissue or body fluid sample of an individual, to provide an indication of the presence of an adenocarcinoma of the colon in the individual. The target adenocarcinoma-associated protein, may be detected, e.g., by reacting the sample with a labeled binding moiety, such as a labeled antibody, capable of specifically binding the protein. In another embodiment, the protein may be detected by isolating one or more colon adenocarcinoma-associated proteins from the sample, separating the proteins by two dimensional gel electrophoresis, and comparing the gel electrophoresis pattern with a standard. The invention provides a wide range of assay methods and compositions which may be used for detecting colon tumors in an individual rapidly and reproducibly, optimally at early stages of the disease.
    Type: Grant
    Filed: December 17, 1993
    Date of Patent: August 20, 1996
    Assignee: Matritech, Inc.
    Inventors: Ying-Jye Wu, Susan K. Keesee