Patents by Inventor Susan Korsmeyer, legal representative

Susan Korsmeyer, legal representative has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stabilized alpha helical peptides and uses thereof
    Patent number: 8198405
    Abstract: Novel polypeptides and methods of making and using the same are described herein. The polypeptides include cross-linking (“hydrocarbon stapling”) moieties to provide a tether between two amino acid moieties, which constrains the secondary structure of the polypeptide. The polypeptides described herein can be used to treat diseases characterized by excessive or inadequate cellular death.
    Type: Grant
    Filed: July 30, 2008
    Date of Patent: June 12, 2012
    Assignees: Dana-Farber Cancer Institute, Inc., President and Fellows of Harvard College
    Inventors: Loren D. Walensky, Stanley J. Korsmeyer, Susan Korsmeyer, legal representative, Gregory Verdine
  • Inhibitors of Taspase1 protease activity
    Patent number: 7964700
    Abstract: A novel protease, Taspase1, is described. Taspase1 is involved in the cleavage of the myeloid/lymphoid or mixed-lineage leukemia (i.e., MLL) protein, which is required for proper HOX gene regulation. Diagnostic methods utilizing Taspase1 are provided, as well as inhibitors of Taspase1. Methods of using the inhibitors of Taspase1 are also described. For example an inhibitor of Taspase1 can be used to treat a cancer, e.g., leukemia, in a subject.
    Type: Grant
    Filed: September 6, 2007
    Date of Patent: June 21, 2011
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: James J. D. Hsieh, Stanley J. Korsmeyer, Susan Korsmeyer, legal representative, Emily H. Y. Cheng
  • Stabilized alpha helical peptides and uses thereof
    Patent number: 7723469
    Abstract: Novel polypeptides and methods of making and using the same are described herein. The polypeptides include cross-linking (“hydrocarbon stapling”) moieties to provide a tether between two amino acid moieties, which constrains the secondary structure of the polypeptide. The polypeptides described herein can be used to treat diseases characterized by excessive or inadequate cellular death.
    Type: Grant
    Filed: November 5, 2004
    Date of Patent: May 25, 2010
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Loren D. Walensky, Stanley J. Korsmeyer, Susan Korsmeyer, legal representative, Gregory Verdine