Abstract: In accordance with the present invention, there is provided a catheter for insertion into a vessel of a patient. The catheter has distal and proximal ends and is made from an elongated flexible shaft also having distal and proximal ends. The shaft has a central lumen extending therethrough which is substantially centered within the shaft. The shaft also having distal and proximal ends and further includes an inflation lumen. The catheter includes an inflatable, preferably non-compliant, outer balloon disposed at its distal end and an inflatable, preferably compliant, inner balloon disposed within the outer balloon. The inner balloon is in fluid communication with the inflation lumen for inflation and deflation thereof. The central lumen extends through the inner balloon. The inner balloon is a centering balloon, whereby when it is at least partially inflated the distal end of said central lumen is substantially centered within the vessel.

Abstract: A device for making folds in an angioplasty balloon while attached to the distal and portion of an angioplasty catheter has a plurality of press members. Each press member has a substantially planar balloon-contacting surface and the press members are interconnected so that the balloon contacting surfaces of opposing press members confront each other. One or more of the press members includes a longitudinal passage formed in an associated balloon contacting surface which receives the catheter shaft so that the balloon may be folded between the surfaces flanking the passage.