Patents by Inventor Susan L. Kozak

Susan L. Kozak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for identifying inhibitors
    Patent number: 7220554
    Abstract: Vif binds to APOBEC3G and induces its rapid degradation, thus eliminating it from cells and preventing its incorporation into HIV-1 virions. Vif contains two domains, one that binds APOBEC3G and another with a conserved SLQ(Y/F)LA motif that mediates APOBEC3G degradation by a proteasome-dependent pathway. Provided herein are methods of exploiting these discoveries to develop compounds useful to inhibit Vif degradation of APOBEC3G, and thereby inhibit viral infection and/or replication.
    Type: Grant
    Filed: May 3, 2004
    Date of Patent: May 22, 2007
    Assignee: Oregon Health and Science University
    Inventors: David Kabat, Mariana Marin, Susan L. Kozak, Kristine M. Rose
  • Methods for identifying inhibitors
    Publication number: 20040234956
    Abstract: Vif binds to APOBEC3G and induces its rapid degradation, thus eliminating it from cells and preventing its incorporation into HIV-1 virions. Vif contains two domains, one that binds APOBEC3G and another with a conserved SLQ(Y/F)LA motif that mediates APOBEC3G degradation by a proteasome-dependent pathway. Provided herein are methods of exploiting these discoveries to develop compounds useful to inhibit Vif degradation of APOBEC3G, and thereby inhibit viral infection and/or replication.
    Type: Application
    Filed: May 3, 2004
    Publication date: November 25, 2004
    Applicant: Oregon Health & Science University
    Inventors: David Kabat, Mariana Marin, Susan L. Kozak, Kristine M. Rose