Patents by Inventor Susan L. O.Brien

Susan L. O.Brien has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating neurodegenerative or myelination disorders using prosaposin-derived peptides
    Publication number: 20030096786
    Abstract: A method for stimulating prosaposin receptor activity in a cell by transfecting the cell with a DNA or RNA molecule encoding prosaposin or a prosaposin receptor agonist. The DNA or RNA molecule is administered either in vivo or used to transfect neural cells or neural stem cells ex vivo followed by reintroduction of the cells into an individual.
    Type: Application
    Filed: November 13, 2002
    Publication date: May 22, 2003
    Inventors: John S. O'Brien, D. Elliot Parks, Susan L. O'Brien
  • Retro-inverso prosaposin-derived peptides and use thereof
    Publication number: 20020128193
    Abstract: Retro-inverso peptide analogs derived from the active neurotrophic region of saposin C which include the amino acid sequence LLEENNDL (all D-amino acids) (SEQ ID NO: 4). These peptides induce neurite outgrowth in vitro, prevent programmed cell death, induce myelination and have an analgesic effect. They are useful in the treatment of central and peripheral nervous system disorders and neuropathic pain.
    Type: Application
    Filed: September 19, 2001
    Publication date: September 12, 2002
    Inventors: John S. O'Brien, David E. Wright, Susan L. O'Brien
  • Method of stimulating prosaposin receptor activity
    Publication number: 20020028783
    Abstract: A method for stimulating prosaposin receptor activity in a cell by transfecting the cell with a DNA or RNA molecule encoding prosaposin or a prosaposin receptor agonist. The DNA or RNA molecule is administered either in vivo or used to transfect neural cells or neural stem cells ex vivo followed by reintroduction of the cells into an individual.
    Type: Application
    Filed: March 9, 2001
    Publication date: March 7, 2002
    Inventors: John S. O'Brien, D. Elliot Parks, Susan L. O.Brien