Patents by Inventor Susan M. De Paul

Susan M. De Paul has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline diacylhydrazine and the use thereof
    Patent number: 10501405
    Abstract: The present disclosure provides crystalline polymorphic and amorphous forms of (R)-3,5-dimethyl-benzoic acid N-(1-tert-butyl-butyl)-N?-(2-ethyl-3-methoxy-benzoyl)-hydrazide (Compound 1) or (S)-3,5-dimethyl-benzoic acid N-(1-tert-butyl-butyl)-N?-(2-ethyl-3-methoxy-benzoyl)-hydrazide (Compound 2). The present disclosure further provides compositions comprising crystalline polymorphic and amorphous forms of Compound 1 or Compound 2 and an excipient, methods of making crystalline polymorphic or amorphous forms of Compound 1 or Compound 2, and methods of using crystalline polymorphic or amorphous forms of Compound 1 or Compound 2 to regulate gene expression in a cell or in a subject.
    Type: Grant
    Filed: January 4, 2017
    Date of Patent: December 10, 2019
    Assignee: INTREXON CORPORATION
    Inventors: Robert E. Hormann, Inna Shulman, Eva Rödel, Rolf Hilfiker, Susan M. De Paul
  • Crystalline Diacylhydrazine and the Use Thereof
    Publication number: 20170107175
    Abstract: The present disclosure provides crystalline polymorphic and amorphous forms of (R)-3,5-dimethyl-benzoic acid N-(1-tert-butyl-butyl)-N?-(2-ethyl-3-methoxy-benzoyl)-hydrazide (Compound 1) or (S)-3,5-dimethyl-benzoic acid N-(1-tert-butyl-butyl)-N?-(2-ethyl-3-methoxy-benzoyl)-hydrazide (Compound 2). The present disclosure further provides compositions comprising crystalline polymorphic and amorphous forms of Compound 1 or Compound 2 and an excipient, methods of making crystalline polymorphic or amorphous forms of Compound 1 or Compound 2, and methods of using crystalline polymorphic or amorphous forms of Compound 1 or Compound 2 to regulate gene expression in a cell or in a subject.
    Type: Application
    Filed: January 4, 2017
    Publication date: April 20, 2017
    Applicant: Intrexon Corporation
    Inventors: Robert E. HORMANN, Inna Shulman, Eva Rodel, Rolf Hilfiker, Susan M. De Paul
  • Crystalline diacylhydrazine and the use thereof
    Patent number: 9604913
    Abstract: The present disclosure provides crystalline polymorphic and amorphous forms of (R)-3,5-dimethyl-benzoic acid N-(1-tert-butyl-butyl)-N?-(2-ethyl-3-methoxy-benzoyl)-hydrazide (Compound 1) or (S)-3,5-dimethyl-benzoic acid N-(1-tert-butyl-butyl)-N?-(2-ethyl-3-methoxy-benzoyl)-hydrazide (Compound 2). The present disclosure further provides compositions comprising crystalline polymorphic and amorphous forms of Compound 1 or Compound 2 and an excipient, methods of making crystalline polymorphic or amorphous forms of Compound 1 or Compound 2, and methods of using crystalline polymorphic or amorphous forms of Compound 1 or Compound 2 to regulate gene expression in a cell or in a subject.
    Type: Grant
    Filed: October 21, 2014
    Date of Patent: March 28, 2017
    Assignee: Intrexon Corporation
    Inventors: Robert E. Hormann, Inna Shulman, Eva Rödel, Rolf Hilfiker, Susan M. De Paul
  • Crystalline Diacylhydrazine and the Use Thereof
    Publication number: 20150045441
    Abstract: The present disclosure provides crystalline polymorphic and amorphous forms of (R)-3,5-dimethyl-benzoic acid N-(1-tert-butyl-butyl)-N?-(2-ethyl-3-methoxy-benzoyl)-hydrazide (Compound 1) or (S)-3,5-dimethyl-benzoic acid N-(1-tert-butyl-butyl)-N?-(2-ethyl-3-methoxy-benzoyl)-hydrazide (Compound 2). The present disclosure further provides compositions comprising crystalline polymorphic and amorphous forms of Compound 1 or Compound 2 and an excipient, methods of making crystalline polymorphic or amorphous forms of Compound 1 or Compound 2, and methods of using crystalline polymorphic or amorphous forms of Compound 1 or Compound 2 to regulate gene expression in a cell or in a subject.
    Type: Application
    Filed: October 21, 2014
    Publication date: February 12, 2015
    Inventors: Robert E. HORMANN, Inna Shulman, Eva Rödel, Rolf Hilfiker, Susan M. De Paul
  • Crystalline diacylhydrazine and the use thereof
    Patent number: 8946294
    Abstract: The present disclosure provides crystalline polymorphic and amorphous forms of (R)-3,5-dimethyl-benzoic acid N-(1-tert-butyl-butyl)-N?-(2-ethyl-3-methoxy-benzoyl)-hydrazide (Compound 1) or (S)-3,5-dimethyl-benzoic acid N-(1-tert-butyl-butyl)-N?-(2-ethyl-3-methoxy-benzoyl)-hydrazide (Compound 2). The present disclosure further provides compositions comprising crystalline polymorphic and amorphous forms of Compound 1 or Compound 2 and an excipient, methods of making crystalline polymorphic or amorphous forms of Compound 1 or Compound 2, and methods of using crystalline polymorphic or amorphous forms of Compound 1 or Compound 2 to regulate gene expression in a cell or in a subject.
    Type: Grant
    Filed: September 7, 2012
    Date of Patent: February 3, 2015
    Assignee: Intrexon Corporation
    Inventors: Robert E. Hormann, Inna Shulman, Eva Rödel, Rolf Hilfiker, Susan M. De Paul
  • Crystalline Diacylhydrazine and the Use Thereof
    Publication number: 20130079413
    Abstract: The present disclosure provides crystalline polymorphic and amorphous forms of (R)-3,5-dimethyl-benzoic acid N-(1-tert-butyl-butyl)-N?-(2-ethyl-3-methoxy-benzoyl)-hydrazide (Compound 1) or (S)-3,5-dimethyl-benzoic acid N-(1-tert-butyl-butyl)-N?-(2-ethyl-3-methoxy-benzoyl)-hydrazide (Compound 2). The present disclosure further provides compositions comprising crystalline polymorphic and amorphous forms of Compound 1 or Compound 2 and an excipient, methods of making crystalline polymorphic or amorphous forms of Compound 1 or Compound 2, and methods of using crystalline polymorphic or amorphous forms of Compound 1 or Compound 2 to regulate gene expression in a cell or in a subject.
    Type: Application
    Filed: September 7, 2012
    Publication date: March 28, 2013
    Applicant: Intrexon Corporation
    Inventors: Robert E. Hormann, Inna Shulman, Eva Rödel, Rolf Hilfiker, Susan M. De Paul