Patents by Inventor Susan Madrid
Susan Madrid has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9382523Abstract: The present invention provides a transformed or transfected Trichoderma reesei cell comprising one or more of: (i) at least one heterologous nucleotide sequence encoding a lipolytic enzyme comprising an amino acid sequence shown as SEQ ID NO: 1 or SEQ ID NO: 2, (ii) at least one heterologous nucleotide sequence encoding a lipolytic enzyme wherein the nucleotide sequence comprises the nucleotide sequence shown as SEQ ID NO: 3 or SEQ ID NO: 4, or (iii) at least one heterologous nucleotide sequence encoding a lipolytic enzyme wherein the nucleotide sequence comprises the nucleotide sequence which hybridizes to SEQ ID NO: 3 or SEQ ID NO: 4 or a nucleotide sequence which is at least 40% sequence identity to SEQ ID NO: 3 or SEQ ID NO: 4; and culturing the cell under conditions to allow for expression of the heterologous nucleotide sequence(s) encoding the lipolytic enzyme.Type: GrantFiled: November 7, 2014Date of Patent: July 5, 2016Assignee: DUPONT NUTRITION BIOSCIENCES APSInventors: Susan Madrid, Cherry Lin, Masoud Rajabi Zargahi, Rikke Høegh Lorentsen, Mai Faurschou Isaksen, Michael Ward
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Publication number: 20150064309Abstract: The present invention provides a transformed or transfected Trichoderma reesei cell comprising one or more of: (i) at least one heterologous nucleotide sequence encoding a lipolytic enzyme comprising an amino acid sequence shown as SEQ ID NO: 1 or SEQ ID NO: 2, (ii) at least one heterologous nucleotide sequence encoding a lipolytic enzyme wherein the nucleotide sequence comprises the nucleotide sequence shown as SEQ ID NO: 3 or SEQ ID NO: 4, or (iii) at least one heterologous nucleotide sequence encoding a lipolytic enzyme wherein the nucleotide sequence comprises the nucleotide sequence which hybridizes to SEQ ID NO: 3 or SEQ ID NO: 4 or a nucleotide sequence which is at least 40% sequence identity to SEQ ID NO: 3 or SEQ ID NO: 4; and culturing the cell under conditions to allow for expression of said heterologous nucleotide sequence(s) encoding said lipolytic enzyme.Type: ApplicationFiled: November 7, 2014Publication date: March 5, 2015Inventors: SUSAN MADRID, CHERRY LIN, MASOUD RAJABI ZARGAHI, RIKKE HØEGH LORENTSEN, MAI FAURSCHOU ISAKSEN, MICHAEL WARD
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Patent number: 8940519Abstract: The present invention provides a transformed or transfected Trichoderma reesei cell comprising one or more of: (i) at least one heterologous nucleotide sequence encoding a lipolytic enzyme comprising an amino acid sequence shown as SEQ ID NO: 1 or SEQ ID NO:2, (ii) at least one heterologous nucleotide sequence encoding a lipolytic enzyme wherein the nucleotide sequence comprises the nucleotide sequence shown as SEQ ID NO: 3 or SEQ ID NO: 4, or (iii) at least one heterologous nucleotide sequence encoding a lipolytic enzyme wherein the nucleotide sequence comprises the nucleotide sequence which hybridizes to SEQ ID NO: 3 or SEQ ID NO: 4 or a nucleotide sequence which is at least 40% sequence identity to SEQ ID NO: 3 or SEQ ID NO: 4; and culturing the cell under conditions to allow for expression of the heterologous nucleotide sequence(s) encoding the lipolytic enzyme.Type: GrantFiled: April 23, 2010Date of Patent: January 27, 2015Assignee: DuPont Nutrition Biosciences ApSInventors: Susan Madrid, Cherry Lin, Masoud Rajabi Zargahi, Rikke Høegh Lorentsen, Mai Faurschou Isaksen, Michael Ward
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Patent number: 8735123Abstract: The present invention relates to a feed supplement comprising a phytase and a lipolytic enzyme, wherein said lipolytic enzyme has lipase activity at a pH in the range of about pH1.5 to about pH3.5.Type: GrantFiled: April 16, 2013Date of Patent: May 27, 2014Assignee: DuPont Nutrition BioSciences ApSInventors: Mai Faurschou Isaksen, Rikke Hoegh Lorentsen, Peter Plumstead, Luis Fernando Romero Millan, Susan Madrid, Cherry Lin, Michael Ward, Masoud Rajabi Zargahi
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Publication number: 20130280228Abstract: The present invention relates to a feed supplement comprising a phytase and a lipolytic enzyme, wherein said lipolytic enzyme has lipase activity at a pH in the range of about pH1.5 to about pH3.5.Type: ApplicationFiled: April 16, 2013Publication date: October 24, 2013Inventors: MAI FAURSCHOU ISAKSEN, RIKKE HOEGH LORENTSEN, PETER PLUMSTEAD, LUIS FERNANDO ROMERO MILLAN, SUSAN MADRID, CHERRY LIN, MICHAEL WARD, MASOUD RAJABI ZARGAHI
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Patent number: 8445250Abstract: The present invention relates to a feed supplement comprising a phytase and a lipolytic enzyme, wherein said lipolytic enzyme has lipase activity at a pH in the range of about pH1.5 to about pH3.5.Type: GrantFiled: April 23, 2010Date of Patent: May 21, 2013Assignee: DuPont Nutrition BioSciences ApSInventors: Mai Faurschou Isaksen, Rikke Høegh Lorentsen, Peter Plumstead, Luis Fernando Romero Millán, Susan Madrid, Cherry Lin, Michael Ward, Masoud Rajabi Zargahi
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Publication number: 20120196002Abstract: The present invention provides a transformed or transfected Trichoderma reesei cell comprising one or more of: (i) at least one heterologous nucleotide sequence encoding a lipolytic enzyme comprising an amino acid sequence shown as SEQ ID NO: 1 or SEQ ID NO:2, (ii) at least one heterologous nucleotide sequence encoding a lipolytic enzyme wherein the nucleotide sequence comprises the nucleotide sequence shown as SEQ ID NO: 3 or SEQ ID NO: 4, or (iii) at least one heterologous nucleotide sequence encoding a lipolytic enzyme wherein the nucleotide sequence comprises the nucleotide sequence which hybridizes to SEQ ID NO: 3 or SEQ ID NO: 4 or a nucleotide sequence which is at least 40% sequence identity to SEQ ID NO: 3 or SEQ ID NO: 4; and culturing the cell under conditions to allow for expression of said heterologous nucleotide sequence(s) encoding said lipolytic enzyme.Type: ApplicationFiled: April 23, 2010Publication date: August 2, 2012Applicant: DANISCO A/SInventors: Susan Madrid, Cherry Lin, Masoud Rajabi Zargahi, Rikke Høegh Lorentsen, Mai Faurschou Isaksen, Michael Ward
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Publication number: 20120107296Abstract: The present invention relates to a feed supplement comprising a phytase and a lipolytic enzyme, wherein said lipolytic enzyme has lipase activity at a pH in the range of about pH1.5 to about pH3.5.Type: ApplicationFiled: April 23, 2010Publication date: May 3, 2012Applicant: DANISCO A/SInventors: Mai Faurschou Isaksen, Rikke Høegh Lorentsen, Peter Plumstead, Luis Fernando Romero Millán, Susan Madrid, Cherry Lin, Michael Ward, Masoud Rajabi Zargahi
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Publication number: 20120058527Abstract: Compositions and methods relating to lipase/acyltransferase enzymes identified in prokaryotes and eukaryotes are described. These enzymes can be used in such applications as lipid stain removal from fabrics and hard surfaces and chemical synthesis reactions.Type: ApplicationFiled: March 19, 2010Publication date: March 8, 2012Applicant: Danisco US Inc.Inventor: Susan Madrid
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Publication number: 20080063783Abstract: A method for the in situ production of an emulsifier in a foodstuff, wherein a lipid acyltransferase is added to the foodstuff. Preferably the emulsifier is produced without an increase or without a substantial increase in the free fatty acid content of the foodstuff. Preferably, the lipid acyltransferase is one which is capable of transferring an acyl group from a lipid to one or more of the following acyl acceptors: a sterol, a stanol, a carbohydrate, a protein or a sub-unit thereof, glycerol. Preferably, in addition to an emulsifier one or more of a stanol ester or a stanol ester or a protein ester or a carbohydrate ester or a diglyceride or a monoglyceride may be produced. One or more of these may function as an additional emulsifier.Type: ApplicationFiled: February 6, 2007Publication date: March 13, 2008Inventors: Arno KREIJ, Susan Madrid, Jorn Mikkelsen, Jorn Soe, Mark Turner, Jonathan Goodwins
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Publication number: 20070254336Abstract: The present invention relates to an isolated nucleic acid sequence coding for a PntR transcription factor comprising a nucleotide sequence that is the same as, or is complementary to, or contains any suitable codon substitutions for any of those of SEQ ID NOs: 1, 3 or 5 or comprises a sequence which has at least 60% sequence homology with any of SEQ ID NOs: 1, 3 or 5, as well as corresponding polypeptides, vector systems and host cells comprising the same. In particular, the invention relates to sequences which are obtained from an Aspergillus, Trichoderma or Penicillium cell. The invention further relates to methods for disrupting PntR expression in a cell as well as methods for expression or production of a POI in a host cell in which PntR expression has been disrupted.Type: ApplicationFiled: April 20, 2007Publication date: November 1, 2007Inventors: Igor Nikolaev, Susan Madrid
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Publication number: 20070122525Abstract: A method for the in situ production of an emulsifier in a foodstuff, wherein a lipid acyltransferase is added to the foodstuff. Preferably the emulsifier is produced without an increase or without a substantial increase in the free fatty acid content of the foodstuff. Preferably, the lipid acyltransferase is one which is capable of transferring an acyl group from a lipid to one or more of the following acyl acceptors: a sterol, a stanol, a carbohydrate, a protein or a sub-unit thereof, glycerol. Preferably, in addition to an emulsifier one or more of a stanol ester or a stanol ester or a protein ester or a carbohydrate ester or a diglyceride or a monoglyceride may be produced. One or more of these may function as an additional emulsifier.Type: ApplicationFiled: July 7, 2006Publication date: May 31, 2007Inventors: Arno Kreij, Susan Madrid, Jorn Mikkelsen, Jorn Soe
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Publication number: 20070026106Abstract: A method for the in situ production of an emulsifier in a foodstuff, wherein a lipid acyltransferase is added to the foodstuff. Preferably the emulsifier is produced without an increase or without a substantial increase in the free fatty acid content of the foodstuff. Preferably, the lipid acyltransferase is one which is capable of transferring an acyl group from a lipid to one or more of the following acyl acceptors: a sterol, a stanol, a carbohydrate, a protein or a sub-unit thereof, glycerol. Preferably, in addition to an emulsifier one or more of a stanol ester or a stanol ester or a protein ester or a carbohydrate ester or a diglyceride or a monoglyceride may be produced. One or more of these may function as an additional emulsifier.Type: ApplicationFiled: July 7, 2006Publication date: February 1, 2007Inventors: Arno Kreij, Susan Madrid, Jorn Mikkelsen, Jorn Soe
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Publication number: 20060078648Abstract: A method for the in situ production of an emulsifier in a foodstuff, wherein a lipid acyltransferase is added to the foodstuff. Preferably the emulsifier is produced without an increase or without a substantial increase in the free fatty acid content of the foodstuff. Preferably, the lipid acyltransferase is one which is capable of transferring an acyl group from a lipid to one or more of the following acyl acceptors: a sterol, a stanol, a carbohydrate, a protein or a sub-unit thereof, glycerol. Preferably, in addition to an emulsifier one or more of a stanol ester or a stanol ester or a protein ester or a carbohydrate ester or a diglyceride or a monoglyceride may be produced. One or more of these may function as an addition emulsifier.Type: ApplicationFiled: July 15, 2005Publication date: April 13, 2006Inventors: Arno De Kreij, Susan Madrid, Jorn Mikkelsen, Jorn Soe
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Publication number: 20060068462Abstract: A method of producing one or more of a carbohydrate ester, a protein ester, a protein subunit ester or a hydroxyl acid ester, which method comprises admixing an acyl donor, an acyl acceptor and water to produce a high water environment comprising 5-98% water, wherein said acyl donor is a lipid substrate selected from one or more of the group consisting of a phospholipid, a lysophospholipid, a triacylglyceride, a diglyceride, a glycolipid or a lysoglycolipid and said acyl acceptor is selected from one ore more of the group consisting of a carbohydrate, a protein, a protein subunit, or a hydroxyl acid; and contacting the admixture with a lipid acyltransferase, such that said lipid acyl transferase catalyses one or both of the following reactions: alcoholysis or transesterification.Type: ApplicationFiled: July 15, 2005Publication date: March 30, 2006Inventors: Arno De Kreij, Susan Madrid, Jorn Mikkelsen, Jorn Soe
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Publication number: 20030068805Abstract: A glucanase enzyme is described. In addition, there is described a nucleotide sequence coding for the glucanase enzyme and a promoter for controlling its expression.Type: ApplicationFiled: July 11, 2002Publication date: April 10, 2003Inventors: Susan Madrid, Preben Rasmussen, Anita Baruch
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Patent number: 6077702Abstract: A glucanase enzyme is described. In addition, there is described a nucleotide sequence coding for the glucanase enzyme and a promoter for controlling its expression.Type: GrantFiled: April 6, 1998Date of Patent: June 20, 2000Assignee: Danisco A/SInventors: Susan Madrid, Preben Rasmussen, Anita Baruch