Patents by Inventor Susan Margaret De Paul

Susan Margaret De Paul has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating diabetes
    Patent number: 9067962
    Abstract: Solid forms of anhydrous (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol are disclosed, in addition to methods of their use in the treatment of various diseases and disorders.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: June 30, 2015
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Susan Margaret De Paul, Anett Perlberg, Matthew Mangzhu Zhao
  • Solid forms of 3-(4-(aminomethyl)-1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamido)phenyl dimethylcarbamate
    Patent number: 8735408
    Abstract: Solid forms of 3-(4-(aminomethyl)-1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamido)phenyl dimethylcarbamate and salts thereof are disclosed. Methods of its use to treat diseases and disorders of the eye are also disclosed.
    Type: Grant
    Filed: November 3, 2011
    Date of Patent: May 27, 2014
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Susan Margaret De Paul, Qun Li, Haiming Zhang
  • HCl Polymorphs of 3-((2-(Dimethylamino)methyl(cyclohex-1-yl))phenol
    Publication number: 20130245125
    Abstract: A crystalline salt of 3-[2-(dimethylamino)methyl(cyclohex-1-yl)] phenol and hydrogen chloride, preferably in a 1:1 composition, including various crystalline forms of this salt, processes for preparing the various crystalline forms of this salt, pharmaceutical compositions containing the various crystalline forms of this salt, and the use of this salt as a pharmacologically active agent in a pharmaceutical composition to treat or inhibit pain or other disorders or disease states.
    Type: Application
    Filed: May 1, 2013
    Publication date: September 19, 2013
    Applicant: GRUENENTHAL GmbH
    Inventors: Michael GRUSS, Andreas FISCHER, Markus KEGEL, Wolfgang HELL, Markus VON RAUMER, Joerg BERGHAUSEN, Susan Margaret DE PAUL
  • METHODS OF TREATING DIABETES
    Publication number: 20130165395
    Abstract: Solid forms of anhydrous (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol are disclosed, in addition to methods of their use in the treatment of various diseases and disorders.
    Type: Application
    Filed: June 22, 2012
    Publication date: June 27, 2013
    Inventors: Susan Margaret De PAUL, Anett PERLBERG, Matthew Mangzhu ZHAO
  • Salt of Dimethylaminomethyl-Phenyl-Cyclohexane and Crystalline Forms Thereof
    Publication number: 20120178809
    Abstract: Novel 3-[2-(dimethylamino)methyl-(cyclohex-1-yl)]-phenol maleate compounds corresponding to formula I and processes for preparing these compounds are provided. Pharmaceutical compositions including these compounds and methods of treating or alleviating pain with these compounds are also provided.
    Type: Application
    Filed: March 14, 2012
    Publication date: July 12, 2012
    Applicant: Gruenenthal GmbH
    Inventors: Michael GRUSS, Wolfgang Hell, Martin Szelagiewicz, Joerg Berghausen, Susan Margaret De Paul, Markus Von Raumer
  • Solid forms of (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol and methods of their use
    Patent number: 8217156
    Abstract: Solid forms of anhydrous (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol are disclosed, in addition to methods of their use in the treatment of various diseases and disorders.
    Type: Grant
    Filed: July 15, 2009
    Date of Patent: July 10, 2012
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Susan Margaret De Paul, Anett Perlberg, Matthew Mangzhu Zhao
  • Salt of Dimethylaminomethyl-Phenyl-Cyclohexane and Crystalline Forms Thereof
    Publication number: 20110046230
    Abstract: Novel 3-[2-(dimethylamino)methyl-(cyclohex-1-yl)]-phenol maleate compounds corresponding to formula I and processes for preparing these compounds are provided. Pharmaceutical compositions including these compounds and methods of treating or alleviating pain with these compounds are also provided.
    Type: Application
    Filed: August 12, 2010
    Publication date: February 24, 2011
    Applicant: Gruenenthal GmbH
    Inventors: Michael GRUSS, Wolfgang Hell, Martin Szelagiewicz, Joerg Berghausen, Susan Margaret De Paul, Markus Von Raumer
  • Salt of dimethylaminomethyl-phenyl-cyclohexane and crystalline forms thereof
    Patent number: 7884247
    Abstract: Novel 3-[2-(dimethylamino)methyl-(cyclohex-1-yl)]-phenol maleate compounds corresponding to formula I and processes for preparing these compounds are provided. Pharmaceutical compositions including these compounds and methods of treating or alleviating pain with these compounds are also provided.
    Type: Grant
    Filed: July 24, 2006
    Date of Patent: February 8, 2011
    Assignee: Gruenenthal GmbH
    Inventors: Michael Gruss, Wolfgang Hell, Martin Szelagiewicz, Joerg Berghausen, Susan Margaret De Paul, Markus Von Raumer
  • SOLID FORMS OF (2S,3R,4R,5S,6R)-2-(4-CHLORO-3-(4-ETHOXYBENZYL)PHENYL)-6-(METHYLTHIO)TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL AND METHODS OF THEIR USE
    Publication number: 20100016422
    Abstract: Solid forms of anhydrous (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol are disclosed, in addition to methods of their use in the treatment of various diseases and disorders.
    Type: Application
    Filed: July 15, 2009
    Publication date: January 21, 2010
    Inventors: Susan Margaret De Paul, Anett Perlberg, Matthew Mangzhu Zhao
  • Bioanalytical recognition surface with optimized recognition element density
    Publication number: 20040253596
    Abstract: The invention relates to a recognition surface on a carrier with an (in relation to the surface) optimal binding capacity for recognizing and binding one or more analytes from one or more samples brought into contact with this surface, wherein
    Type: Application
    Filed: February 27, 2004
    Publication date: December 16, 2004
    Inventors: Michael Pawlak, Gert Ludwig Duveneck, Ning-Ping Huang, Susan Margaret De Paul, Marcus Textor, Rolf Hofer, Eveline Schurmann-Mader