Abstract: The instant invention describes macrocyclic compounds having antiproliferation activity, and methods of treating disorders such as cancer, tumors and cell proliferation related disorders.

Abstract: The invention is directed towards compounds (e.g., Formulae (I)-(IX)), their mechanism of action, processes to prepare the compounds, methods of activating quorum sensing signaling activity, and methods of treating diseases and disorders using the compounds described herein (e.g., Formulae (I)-(IX)).

Abstract: The invention is directed towards compounds (e.g., Formulae (I)-(IX)), their mechanism of action, processes to prepare the compounds, methods of activating quorum sensing signaling activity, and methods of treating diseases and disorders using the compounds described herein (e.g., Formulae (I)-(IX)).

Abstract: A food grade water-soluble arabinoxylan product containing arabinoxylan oligosaccharides and retaining a high amount of bound ferulic acid and other phenolic substances is isolated from corn fiber using an aqueous extraction wherein the pH of the aqueous medium employed for the extraction is adjusted to a selected value after mixing with the corn fiber and prior to the initiation of extraction.

Abstract: Opaque coatings are formed on consumable articles by applying an aqueous composition of one or more trisaccharides such as melezitose (optionally, in combination with one or more other ingredients such as a high intensity sweetener) and then drying the applied aqueous composition. “Frosted” coatings having a reduced sugar (sucrose) content may thereby be obtained.

Abstract: A method for reducing aflatoxin in a grain gluten or corn gluten, the method comprising the steps of: (a) preparing a grain gluten or corn gluten slurry; and (b) treating the grain gluten or corn gluten slurry with ozone wherein the temperature of the grain gluten or corn gluten slurry in step (b) is from about 10 to about 60° C.

Abstract: A food grade water-soluble arabinoxylan product containing arabinoxylan oligosaccharides and retaining a high amount of bound ferulic acid and other phenolic substances is isolated from corn fiber using an aqueous extraction wherein the pH of the aqueous medium employed for the extraction is adjusted to a selected value after mixing with the corn fiber and prior to the initiation of extraction.

Abstract: The present invention relates to a calixarene-based glycosylated compound (I) having the formula: (I) wherein D is independently selected in the group comprising a —CH2-group, an oxygen atom, a sulphur atom, a sulfinyl group or a sulfonyl group, E is independently selected in the group comprising a hydrogen, an alkyl having from 1 to 10 carbon atoms, an aryl having from 6 to 20 carbon atoms, a nitrogen dioxide group, an azide group, an amino group, a guanidinium group, a halogen atom, a —CH2 R group wherein R is a hydroxyl, a halogen, an amino group, a N(alkyl)2 group, a NH(alkyl) group, or E represents a —CO—R? wherein R? is a hydrogen atom, a hydroxyl group or an amino, B represents a A-C group wherein A is independently selected in the group comprising an oxygen atom, a sulfur atom, a NH group or a (CH2)i group, i being an integer from 1 to 10, C is independently selected in the group comprising a hydrogen, an alkyl, an alkenyl, an alkynyl, or C is a group of formula (II).

Abstract: A loyalty system and/or method comprising a mobile computing device and a server wherein the mobile computing device communicates with the server to obtain a loyalty code for use in a loyalty program.

Abstract: The present invention relates to a calixarene-based glycosylated compound (I) having the formula: (I) wherein D is independently selected in the group comprising a —CH2-group, an oxygen atom, a sulphur atom, a sulfinyl group or a sulfonyl group, E is independently selected in the group comprising a hydrogen, an alkyl having from 1 to 10 carbon atoms, an aryl having from 6 to 20 carbon atoms, a nitrogen dioxide group, an azide group, an amino group, a guanidinium group, a halogen atom, a —CH2R group wherein R is a hydroxyl, a halogen, an amino group, a N(alkyl)2 group, a NH(alkyl) group, or E represents a —CO—R? wherein R? is a hydrogen atom, a hydroxyl group or an amino, B represents a A-C group wherein A is independently selected in the group comprising an oxygen atom, a sulfur atom, a NH group or a (CH2)i group, i being an integer from 1 to 10, C is independently selected in the group comprising a hydrogen, an alkyl, an alkenyl, an alkynyl, or C is a group of formula (II).

Abstract: The instant invention describes macrocyclic depsipeptide lyngbyastatins, and methods of treating disorders such as COPD, emphysema, rheumatoid arthritis, and aging related disorders.

Abstract: A support pillow is disclosed which may include a cushion body, a cover and a mat. The cushion body may have a medial region and two opposing arms that define a generally open well, with the cushion body possibly having an outer periphery and an inner periphery adjacent the well. The cover may be disposed over the cushion body such that the cover may conform generally to the shape of the cushion body. The mat may be coupled with at least one of the cushion body and the cover.

Abstract: A support pillow that comprises a pillow body having a medial region and two curved arms that extend from the medial region to define a generally open well. A back rest extends vertically upward from the medial region. This configuration permits an infant to be placed in the open well, with the curved arms of the pillow body supporting the infant from tipping side to side and the back rest supporting the infant's back. Conveniently, the back rest may be incorporated into a slipcover that is placed over the pillow body.

Abstract: The invention generally relates to articles which may be used as headwear for infants that address issues related to flat head syndrome. In a first aspect, an article of headwear for an infant is provided. The headwear is configured to reduce pressure at the rear portion of the head when the infant is lying or reclining in the supine position. The headwear generally includes a head receiving portion having at least a top region and rear region for covering at least the top and rear portions of the head of the infant. In accordance with the invention, the headwear also includes support cushion positioned in the rear region of the head receiving portion. The support cushion is configured to support at least the rear portion of the head of the infant and to at least partially surround a pressure relief region.

Abstract: A support pillow that comprises a pillow body having a medial region and two curved arms that extend from the medial region to define a generally open well. A back rest extends vertically upward from the medial region. This configuration permits an infant to be placed in the open well, with the curved arms of the pillow body supporting the infant from tipping side to side and the back rest supporting the infant's back. Conveniently, the back rest may be incorporated into a slipcover that is placed over the pillow body.

Abstract: A support pillow comprises a cushion body having a medial region and two opposing arms that define a generally open well, with the cushion body having an outer periphery and an inner periphery adjacent the well. An adjustable suspension system is used to suspend one or more objects above the pillow.

Abstract: In one embodiment, a method for making a pillow comprises cutting at least one piece of fabric to form a pair of skins that each comprise a midsection and two arm sections. The two skins are sewn together near their outer edges except for a portion of the mid section to form a shell defining and interior and having a middle region with an opening into the interior and two opposing arms extending from the middle region to form a well region. A fill material is blown into the interior of the shell until the pillow has a firmness defined by an IFD of at least about 20 Newtons with 25% deflection, and the opening in the middle region is closed.

Abstract: A pillow for holding an infant comprises a pillow body having a padded region and a well region. The padded region comprises an upper section, a lower section and two side sections that surround the well region. The padded region further comprises a cover and a fill material stuffed within the cover. The pillow body angles upward from the lower section to the upper section such that when an infant is placed onto the pillow the infant is inclined, with the infant's bottom resting in the well region and the infant's back and head resting on the upper section.

Abstract: A support pillow comprises a cushion body having a medial region and two opposing arms that define a generally open well, with the cushion body having an outer periphery and an inner periphery adjacent the well. A shell encompasses the cushion body. A fabric cover is removably disposed over the shell such that the fabric cover generally conforms to the shell. The fabric cover defines an opening to permit the cover to be placed over the shell, and the fabric covering includes at least one fastener to close the opening once the cover has been placed over the shell.

Abstract: A pillow comprises a pillow body having a midsection and a pair of ends. The pillow body is curved with an average radius of curvature in the range from about 6 inches to about 16 inches. The pillow also has a length from one end to the other that is in the range from about 21 inches to about 42 inches. The pillow is both flexible and firm to permit it to wrap around a user.