Abstract: This invention relates to methods and compositions for bringing about changes in skin pigmentation. More particularly, this invention relates to compounds which affect melanogenesis and can be used as depigmenting agents or as agents for darkening skin utilizing the PAR-2 pathway.

Abstract: This invention relates to methods and compositions for bringing about changes in skin pigmentation. More particularly, this invention relates to compounds which affect melanogenesis and can be used as depigmenting agents or as agents for darkening skin utilizing the PAR-2 pathway.

Abstract: In a preferred embodiemnt the present invention features a composition and method of delivery comprising Glycosaminoglycans encapsulated in a liposomal delivery system for intraarticular administration for the treatment of osteoarthritis In a more preferred embodiemnt the present invention features a composition and method of delivery comprising hyaluronic acid encapsulated in a liposomal delivery system for intraarticular administration for the treatment of osteoarthritis.

Abstract: A self foaming composition comprising: (I) a surfactant mixture comprising (a) at least one anionic surfactant; (b) at least one amphoteric surfactant; and (c) optionally at least one nonionic surfactant; and (II) at least one self foaming agent. The composition is in the form of a liquid crystalline structure and wherein the ratio of (a) to (b) to (c) is selected such that when the surfactant composition is mixed with the self foaming agent a gel consistency is obtained. The cleansing composition is useful in the bath and the shower, as a facial cleanser, and as a shampoo.

Abstract: The present invention relates to a composition for application to the hair or skin which contains a conditioning polymer encapsulated in a lipid vesicle.

Abstract: This invention relates to compositions and methods for enhancing the penetration of topical skin agents into the skin wherein said compositions contain at least one active ingredient, a skin conditioner and a polymeric emulsifier.

Abstract: A self foaming composition comprising: (I) a surfactant mixture comprising (a) at least one anionic surfactant; (b) at least one amphoteric surfactant; and (c) optionally at least one nonionic surfactant; and (II) at least one self foaming agent. The composition is in the form of a liquid crystalline structure and wherein the ratio of (a) to (b) to (c) is selected such that when the surfactant composition is mixed with the self foaming agent a gel consistency is obtained. The cleansing composition is useful in the bath and the shower, as a facial cleanser, and as a shampoo.

Abstract: The present invention relates to a method of making a liposome, the method comprising the steps of: (a) mixing a lipophilic phase and a hydrophilic phase, the lipophilic phase comprising an amphiphilic bilayer-forming substance; and (b) applying a shear force to the mixture to form the liposome; wherein the shear force is created by passing the mixture by a member at a velocity sufficient to create turbulence in the mixture.

Abstract: The present invention relates to a composition for application to the hair or skin which contains a conditioning polymer encapsulated in a lipid vesicle.

Abstract: This invention relates to compositions and methods for enhancing the penetration of topical skin agents into the skin wherein said compositions contain at least one active ingredient, a skin conditioner and a polymeric emulsifier.

Abstract: This invention relates to compositions and methods for enhancing the penetration of topical skin agents into the skin wherein said compositions contain at least one active ingredient, a skin conditioner and a polymeric emulsifier.

Abstract: The present invention relates to a method of making a liposome, said method comprising the steps of: (a) mixing a lipophilic phase and a hydrophilic phase, said lipophilic phase comprising an amphiphilic bilayer-forming substance; and (b) applying a cavitational sheer force to said mixture to form said liposome; wherein said cavitational force is created by contacting said mixture with a member that vibrates at an ultrasonic frequency.

Abstract: This invention relates to compositions and methods for enhancing the penetration of topical skin agents into the skin wherein said compositions contain at least one active ingredient, a skin conditioner and a polymeric emulsifier.