Patents by Inventor Susan Quaggin

Susan Quaggin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF ENHANCING AQUEOUS HUMOR OUTFLOW AND REDUCING INTRAOCULAR PRESSURE
    Publication number: 20230103583
    Abstract: The disclosure relates to methods of enhancing aqueous humor out-flow via the conventional outflow tract in the eye in a subject in need thereof, or reducing intraocular pressure in a subject in need thereof.
    Type: Application
    Filed: February 26, 2021
    Publication date: April 6, 2023
    Inventors: Jing JIN, Pan LIU, Michael RYCZKO, Susan QUAGGIN, Benjamin THOMSON
  • VE-PTP INHIBITION IN GLAUCOMA
    Publication number: 20210283051
    Abstract: The disclosure relates to glaucoma, and more particularly to a mouse model of a VE-PTPlacZ mice bred to a Tie2 haploinsufficient mice and the use of VE-PTP inhibition for neuroprotection of glaucoma symptoms of elevated intraocular pressure. There is a method of producing a mouse model through deletion of a single PTPRB allele in a Tek haploinsufficient mouse. Further, the use of VE-PTP inhibition in the limbal vascular plexus provides neuroprotection from glaucoma symptoms of elevated intraocular pressure.
    Type: Application
    Filed: July 12, 2019
    Publication date: September 16, 2021
    Applicant: Mannin Research, Inc.
    Inventor: Susan QUAGGIN
  • VE-PTP KNOCKOUT
    Publication number: 20190150413
    Abstract: This invention relates to glaucoma, and more particularly to use of VE-PTP-null allele to rescue from the glaucoma symptom of elevated intraocular pressure. This invention also relates to conditional knockout of VE-PTP to rescue from the glaucoma symptom of elevated intraocular pressure expressed in an Angiopoietin 1 and Angiopoietin 2 conditional knockout mouse. This invention also relates to the use of VE-PTP-null alleles.
    Type: Application
    Filed: May 4, 2017
    Publication date: May 23, 2019
    Inventor: Susan QUAGGIN
  • METHODS FOR DETECTING AND TREATING KIDNEY DISEASE
    Publication number: 20100120041
    Abstract: A method is provided for diagnosing and monitoring kidney disease or a predisposition to kidney disease, in a subject comprising detecting pVHL, VEGF-A, CXCR4, integrin ?-1, PDGF-A, HIF1? and/or TGF? in a sample from the subject. Screening methods for test agents for inhibiting kidney disease, and therapeutic applications are also described.
    Type: Application
    Filed: September 30, 2009
    Publication date: May 13, 2010
    Inventor: Susan Quaggin