Patents by Inventor Susan R. Wessler

Susan R. Wessler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9790477
    Abstract: The present invention provides a transposon for use in genetic manipulation of vertebrate and invertebrate cells.
    Type: Grant
    Filed: November 19, 2015
    Date of Patent: October 17, 2017
    Assignee: The Regents of the University of California
    Inventors: Peter W. Atkinson, Susan R. Wessler, Kun Liu
  • Publication number: 20160177334
    Abstract: The present invention provides a transposon for use in genetic manipulation of vertebrate and invertebrate cells.
    Type: Application
    Filed: November 19, 2015
    Publication date: June 23, 2016
    Inventors: Peter W. Atkinson, Susan R. Wessler, Kun Liu
  • Patent number: 8063268
    Abstract: Disclosed are isolated transposable elements, or isolated DNA sequences which encode a transposase protein or a portion of a transposase protein. The isolated transposable elements or the isolated DNA sequences are members of the mPing/Pong family of transposable elements. The invention also relates to a purified transposase protein, or peptide fragments thereof, encoded by such DNA sequences. Such transposable elements are useful in applications such as the stable introduction of a DNA sequence of interest into a eukaryotic cell. The sequence information disclosed herein is useful in the design of oligonucleotide primers which are useful for the isolation of related members of the mPing/Pong family of transposable elements, or for the detection of transpositions of the transposable elements.
    Type: Grant
    Filed: July 10, 2007
    Date of Patent: November 22, 2011
    Assignees: Washington University, University of Georgia Research Foundation, Inc.
    Inventors: Susan R. Wessler, Ning Jiang, Zhirong Bao, Xiaoyu Zhang, Sean R. Eddy
  • Patent number: 7250556
    Abstract: Disclosed are isolated transposable elements, or isolated DNA sequences which encode a transposase protein or a portion of a transposase protein. The isolated transposable elements or the isolated DNA sequences are members of the mPing/Pong family of transposable elements. The invention also relates to a purified transposase protein, or peptide fragments thereof, encoded by such DNA sequences. Such transposable elements are useful in applications such as the stable introduction of a DNA sequence of interest into a eukaryotic cell. The sequence information disclosed herein is useful in the design of oligonucleotide primers which are useful for the isolation of related members of the mPing/Pong family of transposable elements, or for the detection of transpositions of the transposable elements.
    Type: Grant
    Filed: January 16, 2003
    Date of Patent: July 31, 2007
    Assignees: University of Georgia Research Foundation, Inc., Washington University
    Inventors: Susan R. Wessler, Ning Jiang, Zhirong Bao, Xiaoyu Zhang, Sean R. Eddy
  • Publication number: 20040043485
    Abstract: Disclosed are isolated transposable elements, or isolated DNA sequences which encode a transposase protein or a portion of a transposase protein. The isolated transposable elements or the isolated DNA sequences are members of the mPing/Pong family of transposable elements. The invention also relates to a purified transposase protein, or peptide fragments thereof, encoded by such DNA sequences. Such transposable elements are useful in applications such as the stable introduction of a DNA sequence of interest into a eukaryotic cell. The sequence information disclosed herein is useful in the design of oligonucleotide primers which are useful for the isolation of related members of the mPing/Pong family of transposable elements, or for the detection of transpositions of the transposable elements.
    Type: Application
    Filed: January 16, 2003
    Publication date: March 4, 2004
    Inventors: Susan R. Wessler, Ning Jiang, Zhirong Bao, Xiaoyu Zhang, Sean R. Eddy
  • Publication number: 20030104458
    Abstract: Cot-based cloning and sequencing (CBCS) is a method that permits the cloning and sequencing of an organism's sequence complexity at unprecedented efficiency. DNA renaturation kinetics (i.e., Cot) methods are used to fractionate genomic DNA into single-copy and repeat sequence components, each isolated kinetic component is used to construct a corresponding DNA library, and clones from each library are sequenced in numbers proportional to the complexity of the component from which they were derived. For some species, the number of clones that need to be sequenced in order to attain a specific level of coverage via CBCS is less than one-tenth the number required to achieve the same level of coverage using shotgun sequencing (the current means by which genomes are sequenced).
    Type: Application
    Filed: November 13, 2002
    Publication date: June 5, 2003
    Inventors: Daniel G. Peterson, Andrew H. Paterson, Susan R. Wessler
  • Patent number: 6420117
    Abstract: The present invention provides methods of using miniature inverted repeat transposable elements, including producing a DNA fingerprint of an individual, detecting at least one polymorphism between the nucleic acid fragments of two individuals, and correlating the presence of an amplified fragment to a phenotype.
    Type: Grant
    Filed: September 14, 2000
    Date of Patent: July 16, 2002
    Assignee: The University of Georgia Research Foundation, Inc.
    Inventors: Susan R. Wessler, Alexandra M. Casa