Patents by Inventor Susan Radka

Susan Radka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detection and quantitation of nucleic acid molecules in biological samples
    Patent number: 7521184
    Abstract: The present invention concerns processes for the detection and quantitation of nucleic acid molecules, polynucleotides, and/or oligonucleotides in a sample using hybridizationdetection assays, antibody-mediated recognition assays, nucleic acid sensor molecules, chromatographic assays, and/or electrophoresis assays. The present invention specifically concerns processes for the detection and quantitation of double stranded nucleic acid molecules, polynucleotides, and/or oligonucleotides in a sample using hybridization-detection assays. The nucleic acid molecules, polynucleotides, and/or oligonucleotides can include molecules that mediate RNA interference, such as short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA), and short hairpin RNA (shRNA) molecules.
    Type: Grant
    Filed: August 17, 2004
    Date of Patent: April 21, 2009
    Assignee: Sirna Therapeutics, Inc.
    Inventors: Susan Radka, Zinnen Shawn, Vasant Jadhav, James McSwiggen, Narendra Vaish
  • Detection and Quantitation of Nucleic Acid Molecules in Biological Samples
    Publication number: 20080050721
    Abstract: The present invention concerns processes for the detection and quantitation of nucleic acid molecules, polynucleotides, and/or oligonucleotides in a sample using hybridizationdetection assays, antibody-mediated recognition assays, nucleic acid sensor molecules, chromatographic assays, and/or electrophoresis assays. The present invention specifically concerns processes for the detection and quantitation of double stranded nucleic acid molecules, polynucleotides, and/or oligonucleotides in a sample using hybridization-detection assays. The nucleic acid molecules, polynucleotides, and/or oligonucleotides can include molecules that mediate RNA interference, such as short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA), and short hairpin RNA (shRNA) molecules.
    Type: Application
    Filed: August 17, 2004
    Publication date: February 28, 2008
    Applicant: Sirna Therapeutics, Inc.
    Inventors: Susan Radka, Zinnen Shawn, Vasant Jadhav, James McSwiggen, Narendra Vaish
  • Antibodies having specificity for 2?-C-allyl nucleic acids
    Patent number: 7071311
    Abstract: The present invention relates to antibodies, antibody conjugates, and compositions thereof, methods of antibody synthesis, and applications of antibodies useful for detecting the presence of nucleic acid molecules in vivo, such as in a clinical setting. The antibodies of the invention are also useful as screening agents which allow the selection of candidate therapeutic molecules for optimum bioavailability and/or activity, and as delivery agents for cell and tissue specific delivery of nucleic acid molecules.
    Type: Grant
    Filed: February 12, 2003
    Date of Patent: July 4, 2006
    Assignee: Sirna Therapeutics, Inc.
    Inventors: Susan Radka, Leonid Beigelman, Haeberli Peter
  • Antibodies having specificity for nucleic acids
    Publication number: 20050042632
    Abstract: The present invention relates to antibodies, antibody conjugates, and compositions thereof, methods of antibody synthesis, and applications of antibodies useful for detecting the presence of nucleic acid molecules, including short interfering RNA (siRNA) molecules, in vivo, such as in a clinical setting. The antibodies of the invention are also useful as screening agents which allow the selection of candidate therapeutic molecules for optimum bioavailability and/or activity, and as delivery agents for cell and tissue specific delivery of nucleic acid molecules.
    Type: Application
    Filed: April 8, 2004
    Publication date: February 24, 2005
    Applicant: Sirna Therapeutics, Inc.
    Inventor: Susan Radka
  • Methods of screening subjects for expression of soluble receptors of vascular endothelial growth factor (VEGF) for use in managing treatment and determining prognostic outcome
    Publication number: 20030232400
    Abstract: This invention relates generally to compounds and methods relating to detection of soluble VEGFR expression for generating prognostic criteria useful in establishing methods of treatment in cancer patients. In the method of the present invention, soluble VEGFR levels are utilized as a means by which cancer can be detected, efficacy of cancer therapies can be evaluated, prognosis of a subject can be predicted, and new anti-cancer therapies can be discovered.
    Type: Application
    Filed: May 15, 2003
    Publication date: December 18, 2003
    Inventors: Susan Radka, Roger Aitchison, Pamela Pavco
  • Antibodies having specificity for nucleic acids
    Publication number: 20030228590
    Abstract: The present invention relates to antibodies, antibody conjugates, and compositions thereof, methods of antibody synthesis, and applications of antibodies useful for detecting the presence of nucleic acid molecules in vivo, such as in a clinical setting. The antibodies of the invention are also useful as screening agents which allow the selection of candidate therapeutic molecules for optimum bioavailability and/or activity, and as delivery agents for cell and tissue specific delivery of nucleic acid molecules.
    Type: Application
    Filed: February 12, 2003
    Publication date: December 11, 2003
    Inventors: Susan Radka, Leonid Beigelman, Haeberli Peter