Abstract: Methods and kits for detecting antibodies (e.g., anti-drug antibodies). Such methods and kits permit the detection of, for example, anti-drug antibodies in human body fluids, such as blood, plasma and serum.

Abstract: The invention provides methods for reducing undesired immune responses, such as anti-drug antibody (ADA) responses and other T- and/or B-cell-mediated immune responses, in patients by using treatment with methotrexate.

Abstract: The invention provides methods for reducing undesired immune responses, such as anti-drug antibody (ADA) responses and other T- and/or B-cell-mediated immune responses, in patients by using treatment with methotrexate.

Abstract: Methods and kits for detecting antibodies (e.g., anti-drug antibodies). Such methods and kits permit the detection of, for example, anti-drug antibodies in human body fluids, such as blood, plasma and serum.

Abstract: Methods and kits for detecting antibodies (e.g., anti-drug antibodies). Such methods and kits permit the detection of, for example, anti-drug antibodies in human body fluids, such as blood, plasma and serum.

Abstract: The invention provides methods for reducing undesired immune responses, such as anti-drug antibody (ADA) responses and other T- and/or B-cell-mediated immune responses, in patients by using treatment with methotrexate.

Abstract: Methods and kits for detecting antibodies (e.g., anti-drug antibodies). Such methods and kits permit the detection of, for example, anti-drug antibodies in human body fluids, such as blood, plasma and serum.

Abstract: Methods and kits for detecting antibodies (e.g., anti-drug antibodies). Such methods and kits permit the detection of, for example, anti-drug antibodies in human body fluids, such as blood, plasma and serum.

Abstract: Methods and kits for detecting antibodies (e.g., anti-drug antibodies). Such methods and kits permit the detection of, for example, anti-drug antibodies in human body fluids, such as blood, plasma and serum.

Abstract: A torsion bar having progressive load limiting characteristics for use in a vehicle restraint system is provided. The torsion bar includes a longitudinal main body portion having a first end for mounting to a belt retractor spindle and a second end for being engaged and disengaged with a seatbelt locking mechanism. The main body portion includes a longitudinal slot extending transversely therethrough that defines an opening therein. The torsion bar will twist in response to a first torsional load, which will cause the opening to become closed. When the opening becomes closed, the torsion bar with withstand twisting up to a second torsional load, where the torsion bar will twist again in response to the second torsional load.

Abstract: A torsion bar having progressive load limiting characteristics for use in a vehicle restraint system is provided. The torsion bar includes a longitudinal main body portion having a first end for mounting to a belt retractor spindle and a second end for being engaged and disengaged with a seatbelt locking mechanism. The main body portion includes a longitudinal slot extending transversely therethrough that defines an opening therein. The torsion bar will twist in response to a first torsional load, which will cause the opening to become closed. When the opening becomes closed, the torsion bar with withstand twisting up to a second torsional load, where the torsion bar will twist again in response to the second torsional load.

Abstract: The invention provides methods for reducing undesired immune responses, such as anti-drug antibody (ADA) responses and other T- and/or B-cell-mediated immune responses, in patients by using treatment with methotrexate.

Abstract: A seat belt retractor (100) having a rotationally mounted spool (120) with a seat belt windable thereon and a pretensioner (300) for winding the spool in a belt winding direction to rewind the seat belt upon the spool; the pretensioner comprising a rack and pinion mechanism (350) activated by a pyrotechnic element (400) for causing a clutch assembly (200) to change state from a disengaged mode to an engaged mode in which the clutch assembly drivingly engages the spool.

Abstract: An electromechanical seat belt retractor has a seat belt retractor assembly having a spool rotationally moveable about an axis of rotation for winding and unwinding a seat belt; a motor for selectively rotating the spool; a clutch including an over-clutch driven by the motor through one or more gears; the clutch being coaxially aligned with the axis of rotation of the spool and linearly spaced from the spool; and wherein upon a forward actuation of the motor a clutch plate of the clutch linearly moves to engage the spool coupling to the spool and thereafter rotating the spool about the axis to initiate a winding of the seat belt. After the clutch plate engages the spool a reversal of the motor linearly moves the clutch plate away from the spool disengaging the spool. Preferably the clutch means is a Bendix type clutch assembly. In a preferred embodiment, the clutch plate first engages an over-clutch is fixed in a locking engagement to the spool.

Abstract: A seat belt retractor (100) having a rotationally mounted spool (120) with a seat belt windable thereon and a pretensioner (300) for winding the spool in a belt winding direction to rewind the seat belt upon the spool; the pretensioner comprising a rack and pinion mechanism (350) activated by a pyrotechnic element (400) for causing a clutch assembly (200) to change state from a disengaged mode to an engaged mode in which the clutch assembly drivingly engages the spool.

Abstract: A seat belt retractor (20) characterized by low mass and low operating noise, resistant to dust, moisture, and corrosion comprising: an integrally formed, quadrilaterally shaped main body portion (24). In the preferred embodiment of the invention the frame is injection molded using 50% or greater long glass fiber plastic or die cast or injection molded metal. A spring housing wall and wall of a mechanism cover are also integrally formed in the sides of the retractor. Positioned within the spring housing wall is a spring coil guide, as well as an integrally formed anchor, which is used to hold the outer end of a rewind spring. The mechanism side of the frame further includes an integrally formed post or pin to pivotally support a locking pawl.

Abstract: ABSTRACT Methods of preparing pre-moistened wipes with an improved feel and softness are disclosed. The lotion of the pre-moistened wipes may be substantially free of polyacrylate homopolymers and polyacrylate copolymers.

Abstract: A seat belt retractor (20) characterized by low mass and low operating noise, resistant to dust, moisture, and corrosion comprising: an integrally formed, quadrilaterally shaped main body portion (24). In the preferred embodiment of the invention the frame is injection molded using 50% or greater long glass fiber plastic or die cast or injection molded metal. A spring housing wall and wall of a mechanism cover are also integrally formed in the sides of the retractor. Positioned within the spring housing wall is a spring coil guide, as well as an integrally formed anchor, which is used to hold the outer end of a rewind spring. The mechanism side of the frame further includes an integrally formed post or pin to pivotally support a locking pawl.

Abstract: A seat belt retractor (20) characterized by low mass and low operating noise, resistant to dust, moisture, and corrosion comprising: an integrally formed, quadrilaterally shaped main body portion (24). In the preferred embodiment of the invention the frame is injection molded using 50% or greater long glass fiber plastic or die cast or injection molded metal. A spring housing wall and wall of a mechanism cover are also integrally formed in the sides of the retractor. Positioned within the spring housing wall is a spring coil guide, as well as an integrally formed anchor, which is used to hold the outer end of a rewind spring. The mechanism side of the frame further includes an integrally formed post or pin to pivotally support a locking pawl.

Abstract: A seat belt retractor (20) characterized by low mass and low operating noise, resistant to dust, moisture, and corrosion comprising: an integrally formed, quadrilaterally shaped main body portion (24). In the preferred embodiment of the invention the frame is injection molded using 50% or greater long glass fiber plastic or die cast or injection molded metal. A spring housing wall and wall of a mechanism cover are also integrally formed in the sides of the retractor. Positioned within the spring housing wall is a spring coil guide, as well as an integrally formed anchor, which is used to hold the outer end of a rewind spring. The mechanism side of the frame further includes an integrally formed post or pin to pivotally support a locking pawl.