Patents by Inventor Susan Rippin

Susan Rippin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IAP INHIBITORS
    Publication number: 20110288116
    Abstract: The present invention describes compounds of the following formula: processes for their preparation, pharmaceutical compositions containing them, and their use in therapy. The compounds of the present invention inhibit IAPs (inhibitors of apoptosis proteins) and thus are useful in the treatment of cancer, autoimmune diseases and other disorders where a defect in apoptosis is implicated.
    Type: Application
    Filed: January 15, 2009
    Publication date: November 24, 2011
    Applicant: TETRALOGIC PHARMACEUITCAL CORPORATION
    Inventors: Stephen M. Condon, Matthew G. Laporte, Yijun Deng, Susan Rippin, Yu-Hua Lee, Thomas Haimowitz
  • Compounds, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
    Publication number: 20080103181
    Abstract: Methods of using di, tri, and tetracyclic acylhydrazide derivatives and analogs, as well as pharmaceutical compositions containing the same, for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases cased by the orthopoxvirus.
    Type: Application
    Filed: June 18, 2004
    Publication date: May 1, 2008
    Applicant: Siga Technologies, Inc.
    Inventors: Robert Jordan, Thomas Bailey, Susan Rippin
  • IAP INHIBITORS
    Publication number: 20080021066
    Abstract: Smac mimetics that inhibit IAPs.
    Type: Application
    Filed: July 24, 2007
    Publication date: January 24, 2008
    Inventors: Stephen Condon, Matthew LaPorte, Yijun Deng, Susan Rippin
  • DIMERIC IAP INHIBITORS
    Publication number: 20080020986
    Abstract: Smac mimetics that inhibit IAPs.
    Type: Application
    Filed: July 24, 2007
    Publication date: January 24, 2008
    Inventors: Stephen Condon, Matthew LaPorte, Yijun Deng, Susan Rippin
  • Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
    Publication number: 20080004452
    Abstract: Methods of using di, tri, and tetracyclic acylhydrazide derivatives and analogs, as well as pharmaceutical compositions containing the same, for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases cased by the orthopoxvirus.
    Type: Application
    Filed: April 23, 2007
    Publication date: January 3, 2008
    Applicant: SiGA Technologies, Inc.
    Inventors: Robert Jordan, Thomas Bailey, Susan Rippin, Dongcheng Dai
  • Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
    Publication number: 20070287735
    Abstract: Methods of using di, tri, and tetracyclic acylhydrazide derivatives and analogs, as well as pharmaceutical compositions containing the same, for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases cased by the orthopoxvirus.
    Type: Application
    Filed: April 23, 2007
    Publication date: December 13, 2007
    Applicant: SiGA Technologies, Inc.
    Inventors: Robert Jordan, Thomas Bailey, Susan Rippin, Dongcheng Dai
  • BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES
    Publication number: 20070231318
    Abstract: The present invention relates to novel benzofuran derivatives and analogs, as well as compositions containing the same and to the use thereof for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the hepatitis C virus.
    Type: Application
    Filed: May 24, 2007
    Publication date: October 4, 2007
    Inventors: Ashis Saha, Christopher Burns, Alfred Del Vecchio, Thomas Bailey, Jason Reinhardt, Bheemashankar Kulkarni, Thomas Faitg, Hao Feng, Susan Rippin, Charles Blackledge, David Rys, Thomas Lessen, John Swestock, Yijum Deng, Theodore Nitz
  • Compounds, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
    Publication number: 20060235051
    Abstract: Methods of using di, tri, and tetracyclic acylhydrazide derivatives and analogs, as well as pharmaceutical compositions containing the same, for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases cased by the orthopoxvirus.
    Type: Application
    Filed: June 18, 2004
    Publication date: October 19, 2006
    Applicant: Siga Technologies, Inc.
    Inventors: Robert Jordan, Thomas Bailey, Susan Rippin
  • Dimeric IAP inhibitors
    Publication number: 20060194741
    Abstract: Molecular mimics of Smac are capable of modulating apoptosis through their interaction with cellular IAPs (inhibitor of apoptosis proteins). The mimetics are based on a monomer or dimer of the N-terminal tetrapeptide of IAP-binding proteins, such as Smac/DIABLO, Hid, Grim and Reaper, which interact with a specific surface groove of LAP. Also disclosed are methods of using these peptidomimetics for therapeutic purposes.
    Type: Application
    Filed: February 27, 2006
    Publication date: August 31, 2006
    Inventors: Stephen Condon, Matthew LaPorte, Yijun Deng, Susan Rippin
  • IAP binding compounds
    Publication number: 20060025347
    Abstract: IAP binding molecules and compositions including these are disclosed. The IAP binding molecules interact with IAPs (inhibitor of apoptosis proteins) in cells and may be used to modify apoptosis in cells treated with such molecules. Embodiments of these compounds have a Kd of less that 0.1 micromolar. Methods of using these IAP binding molecules for therapeutic, diagnostic, and assay purposes are also disclosed.
    Type: Application
    Filed: July 15, 2005
    Publication date: February 2, 2006
    Inventors: Stephen Condon, Matthew LaPorte, Yijun Deng, Susan Rippin