Patents by Inventor Susan S. Taylor

Susan S. Taylor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Screening assay to identify modulators of protein kinase A
    Patent number: 7892776
    Abstract: Methods for screening compounds for their activity as a protein kinase A modulators are provided. The methods are based on fluorescence polarization of peptide probes to identify drug candidates that act by activating or inhibiting the catalytic function of PKA. In certain embodiments, the methods are adapted for high throughput screening.
    Type: Grant
    Filed: May 5, 2008
    Date of Patent: February 22, 2011
    Assignee: The Regents of the University of California
    Inventors: Susan S. Taylor, Sanjay A. Saldanha
  • Screening assay to identify non-ATP-competitors targeting protein kinase A
    Publication number: 20090061442
    Abstract: Methods for screening compounds for their activity as a protein kinase A modulators are provided. The methods are based on fluorescence polarization of peptide probes to identify drug candidates that act by activating or inhibiting the catalytic function of PKA. In certain embodiments, the methods are adapted for high throughput screening.
    Type: Application
    Filed: May 5, 2008
    Publication date: March 5, 2009
    Inventors: Susan S. Taylor, Sanjay A. Saldanha
  • Detection of analytes using fluorescent energy transfer
    Patent number: 5439797
    Abstract: The invention provides labeled proteins suitable for determining the presence of cAMP, other second messengers and organic molecules. The proteins are separately labeled with fluorochromes which, when in close spatial proximity, preferably, less than about 6 nm, interact through the transfer of energy from one fluorochrome to the other.A composition of matter, (S.sub.1.A).sub.n1 (S.sub.2.D).sub.n2 is provided wherein S.sub.1 and S.sub.2 are two proteins which are associated in one state and substantially disassociated in another, the equilibrium between which is controlled by the free concentration of an analyte, and A and D are fluorochromes, the emission wavelength of fluorochrome D overlapping the excitation wavelength of fluorochrome A and the distance between A and D being in sufficiently close proximity to allow the radiationless transfer of energy between the fluorochromes.
    Type: Grant
    Filed: August 30, 1993
    Date of Patent: August 8, 1995
    Assignee: The Regents of the University of California
    Inventors: Roger Y. Tsien, Susan S. Taylor, Stephen R. Adams, Ying Ji