Patents by Inventor Susan Tam

Susan Tam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AGENTS THAT INTERFERE WITH IL-1BETA RECEPTOR SIGNALLING
    Publication number: 20230068783
    Abstract: The present disclosure relates to antibodies that specifically bind and neutralize interleukin-1? (IL-1?), and to the use of such antibodies for the therapeutic treatment of IL-1?-mediated diseases and disorders.
    Type: Application
    Filed: July 9, 2020
    Publication date: March 2, 2023
    Applicant: TAVOTEK BIOTHERAPEUTICS (HONG KONG) LIMITED
    Inventors: Di ZHANG, Susan TAM, Minseon CHO, Lihua SHI, Man-Cheong FUNG
  • Anti-IL-6 Antibody
    Publication number: 20220048985
    Abstract: Anti-IL-6 antibodies and antirheumatics are useful to treat and suppress IL-6 related conditions, such as rheumatoid arthritis.
    Type: Application
    Filed: November 1, 2021
    Publication date: February 17, 2022
    Inventors: Yan Chen, Debra Gardner, David M. Knight, Michael W. Lark, Bailin Liang, David M. Marquis, David J. Shealy, Eric Michael Smith, Xiao-yu R. Song, Vedrana Stojanovic-Susulic, Raymond Sweet, Susan Tam, Alain P. Vasserot, Sheng-Jiun Wu, Jing Yang
  • Methods of suppressing rheumatoid arthritis using an anti-IL-6 antibody
    Patent number: 11180549
    Abstract: Anti-IL-6 antibodies and antirheumatics are useful to treat and suppress IL-6 related conditions, such as rheumatoid arthritis.
    Type: Grant
    Filed: December 17, 2019
    Date of Patent: November 23, 2021
    Assignees: Janssen Biotech, Inc., Applied Molecular Evolution, Inc
    Inventors: Yan Chen, Debra Gardner, David M. Knight, Michael W. Lark, Bailin Liang, David M. Marquis, David J. Shealy, Eric Michael Smith, Xiao-yu R. Song, Vedrana Stojanovic-Susulic, Raymond Sweet, Susan Tam, Alain P. Vasserot, Sheng-Jiun Wu, Jing Yang
  • Antibody Fc Mutants with Ablated Effector Functions
    Publication number: 20210155711
    Abstract: Antibody and other Fc-containing molecules with variations in the Fc region with reduced binding to Fc gamma receptors and resulting activity and can be used in the treatment of various diseases and disorders.
    Type: Application
    Filed: January 15, 2021
    Publication date: May 27, 2021
    Inventors: Stephen McCarthy, Bernard Scallon, William Strohl, Susan Tam, Omid Vafa
  • Antibody Fc mutants with ablated effector functions
    Patent number: 10894836
    Abstract: Antibody and other Fc-containing molecules with variations in the Fc region with reduced binding to Fc gamma receptors and resulting activity and can be used in the treatment of various diseases and disorders.
    Type: Grant
    Filed: July 17, 2018
    Date of Patent: January 19, 2021
    Assignee: Janssen Biotech, Inc.
    Inventors: McCarthy Stephen, Bernard Scallon, William Strohl, Susan Tam, Omid Vafa
  • Methods of Suppressing Rheumatoid Arthritis Using an Anti-IL-6 Antibody
    Publication number: 20200115445
    Abstract: Anti-IL-6 antibodies and antirheumatics are useful to treat and suppress IL-6 related conditions, such as rheumatoid arthritis.
    Type: Application
    Filed: December 17, 2019
    Publication date: April 16, 2020
    Inventors: Yan Chen, Debra Gardner, David M. Knight, Michael W. Lark, Bailin Liang, David M. Marquis, David J. Shealy, Eric Michael Smith, Xiao-yu R. Song, Vedrana Stojanovic-Susulic, Raymond Sweet, Susan Tam, Alain P. Vasserot, Sheng-Jiun Wu, Jing Yang
  • Antibody Fc Mutants with Ablated Effector Functions
    Publication number: 20180319893
    Abstract: Antibody and other Fc-containing molecules with variations in the Fc region with reduced binding to Fc gamma receptors and resulting activity and can be used in the treatment of various diseases and disorders.
    Type: Application
    Filed: July 17, 2018
    Publication date: November 8, 2018
    Inventors: McCarthy Stephen, Bernard Scallon, William Strohl, Susan Tam, Omid Vafa
  • Antibody Fc mutants with ablated effector functions
    Patent number: 10053513
    Abstract: Antibody and other Fc-containing molecules with variations in the Fc region with reduced binding to Fc gamma receptors and resulting activity and can be used in the treatment of various diseases and disorders.
    Type: Grant
    Filed: August 5, 2015
    Date of Patent: August 21, 2018
    Assignee: Janssen Biotech, Inc.
    Inventors: Stephen McCarthy, Bernard Scallon, Susan Tam, William Strohl, Omid Vafa
  • Methods of Suppressing Rheumatoid Arthritis Using An Anti-IL-6 Antibody
    Publication number: 20170253651
    Abstract: Anti-IL-6 antibodies and antirheumatics are useful to treat and suppress IL-6 related conditions, such as rheumatoid arthritis.
    Type: Application
    Filed: March 17, 2017
    Publication date: September 7, 2017
    Inventors: Yan Chen, Debra Gardner, David M. Knight, Michael W. Lark, Bailin Liang, David M. Marquis, David J. Shealy, Eric Michael Smith, Xioa-yu R. Song, Vedrana Stojanovic-Susulic, Raymond W. Sweet, Susan Tam, Alain P. Vasserot, Sheng-Jiun Wu, Jing Yang
  • Pen-injector device containing anti-IL-6 antibodies
    Patent number: 9631016
    Abstract: A pen-injector device comprising an anti-IL-6 antibody with a liquid formulation have applications in diagnostic and/or therapeutic compositions, methods and devices.
    Type: Grant
    Filed: April 19, 2016
    Date of Patent: April 25, 2017
    Assignees: Janssen Biotech, Inc., Applied Molecular Evolution
    Inventors: Yan Chen, Debra Gardner, David M. Knight, Michael W. Lark, Bailin Liang, David M. Marquis, David J. Shealy, Eric Michael Smith, Xiao-yu R. Song, Vedrana Stojanovic-Susulic, Raymond W. Sweet, Susan Tam, Alain P. Vasserot, Sheng-Jiun Wu, Jing Yang
  • Anti-IL-6 Antibodies, Compositions, Methods and Uses
    Publication number: 20160222104
    Abstract: A pen-injector device comprising an anti-IL-6 antibody with a liquid formulation have applications in diagnostic and/or therapeutic compositions, methods and devices.
    Type: Application
    Filed: April 19, 2016
    Publication date: August 4, 2016
    Inventors: Yan Chen, Debra Gardner, David M. Knight, Michael W. Lark, Bailin Liang, David M. Marquis, David J. Shealy, Eric Michael Smith, Xiao-yu R. Song, Vedrana Stojanovic-Susulic, Raymond W. Sweet, Susan Tam, Alain P. Vasserot, Sheng-Jiun Wu, Jing Yang
  • Anti-IL-6 antibodies, compositions, methods and uses
    Patent number: 9340613
    Abstract: An anti-IL-6 antibody, including isolated nucleic acids that encode at least one anti-IL-6 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
    Type: Grant
    Filed: December 4, 2013
    Date of Patent: May 17, 2016
    Assignees: Janssen Biotech, Inc., Applied Molecular Evolution
    Inventors: Yan Chen, Debra Gardner, David M. Knight, Michael W. Lark, Bailin Liang, David M. Marquis, David J. Shealy, Eric Michael Smith, Xiao-yu R. Song, Vedrana Stojanovic-Susulic, Raymond W. Sweet, Susan Tam, Alain P. Vasserot, Sheng-Jiun Wu, Jing Yang
  • Antibody Fc Mutants with Ablated Effector Functions
    Publication number: 20150337053
    Abstract: Antibody and other Fc-containing molecules with variations in the Fc region with reduced binding to Fc gamma receptors and resulting activity and can be used in the treatment of various diseases and disorders.
    Type: Application
    Filed: August 5, 2015
    Publication date: November 26, 2015
    Inventors: Stephen McCarthy, Bernard Scallon, Susan Tam, William Strohl, Omid Vafa
  • Anti-IL-6 antibodies, compositions, methods and uses
    Publication number: 20060257407
    Abstract: An anti-IL-6 antibody, including isolated nucleic acids that encode at least one anti-IL-6 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
    Type: Application
    Filed: April 28, 2006
    Publication date: November 16, 2006
    Inventors: Yan Chen, Debra Gardner, David Knight, Michael Lark, Bailin Liang, David Shealy, Xiao-Yu Song, Vedrana Stojanovic-Susulic, Raymond Sweet, Susan Tam, Sheng-Jiun Wu, Jing Yang, David Marquis, Eric Smith, Alain Vasserot
  • Method of promoting graft survival with anti-tissue factor antibodies
    Publication number: 20050106147
    Abstract: The present invention is directed to a method of using function blocking tissue factor antibodies to enhance graft survival in mammals. Function blocking antibodies having the effect of blocking activated tissue factor (TF), TF and its ligand FVII as either the inactive TF:FVII or active TF:FVIIa complex, or block the formation of the TF:FVIIa:FX ternary complex are useful in the method. These properties provide a therapy that has directed action towards thrombotic events involving tissue-plasma interactions but does not prevent the intrinsic pathway for coagulation. Activated TF arises on cells, tissues, and organs during or after transplantation and is a major cause of graft loss.
    Type: Application
    Filed: August 27, 2004
    Publication date: May 19, 2005
    Inventors: Robert Jordan, Susan Tam, Janet Davis, Mark Zimmerman, Gang Xu, Norma Kenyon