Patents by Inventor Susan V. Cannon-Carlson

Susan V. Cannon-Carlson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pegylated interleukin-10
    Patent number: 10471126
    Abstract: Interleukin-10 (IL-10) conjugated via a linker to one or more polyethylene glycol (PEG) molecules at a single amino acid residue of the IL-10, and a method for preparing the same, are provided. The method produces a stable mono-pegylated IL-10, which retains IL-10 activity, where pegylation is selective for the N-terminus on one subunit of IL-10 with little or no formation of monomeric IL-10. The method also provides a substantially homogenous population of mono-PEG-IL-10.
    Type: Grant
    Filed: February 6, 2018
    Date of Patent: November 12, 2019
    Assignee: Merck Sharp & Dohme Ltd
    Inventors: Seoju Lee, David C. Wylie, Susan V. Cannon-Carlson
  • Pegylated Interleukin-10
    Publication number: 20180250363
    Abstract: Interleukin-10 (IL-10) conjugated via a linker to one or more polyethylene glycol (PEG) molecules at a single amino acid residue of the IL-10, and a method for preparing the same, are provided. The method produces a stable mono-pegylated IL-10, which retains IL-10 activity, where pegylation is selective for the N-terminus on one subunit of IL-10 with little or no formation of monomeric IL-10. The method also provides a substantially homogenous population of mono-PEG-IL-10.
    Type: Application
    Filed: February 6, 2018
    Publication date: September 6, 2018
    Inventors: Seoju Lee, David C. Wylie, Susan V. Cannon-Carlson
  • Pegylated interleukin-10
    Patent number: 9925245
    Abstract: Interleukin-10 (IL-10) conjugated via a linker to one or more polyethylene glycol (PEG) molecules at a single amino acid residue of the IL-10, and a method for preparing the same, are provided. The method produces a stable mono-pegylated IL-10, which retains IL-10 activity, where pegylation is selective for the N-terminus on one subunit of IL-10 with little or no formation of monomeric IL-10. The method also provides a substantially homogenous population of mono-PEG-IL-10.
    Type: Grant
    Filed: December 10, 2015
    Date of Patent: March 27, 2018
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Seoju Lee, David C. Wylie, Susan V. Cannon-Carlson
  • Pegylated Interleukin-10
    Publication number: 20160166647
    Abstract: Interleukin-10 (IL-10) conjugated via a linker to one or more polyethylene glycol (PEG) molecules at a single amino acid residue of the IL-10, and a method for preparing the same, are provided. The method produces a stable mono-pegylated IL-10, which retains IL-10 activity, where pegylation is selective for the N-terminus on one subunit of IL-10 with little or no formation of monomeric IL-10. The method also provides a substantially homogenous population of mono-PEG-IL-10.
    Type: Application
    Filed: December 10, 2015
    Publication date: June 16, 2016
    Inventors: Seoju Lee, David C. Wylie, Susan V. Cannon-Carlson
  • Method for reducing the appearance of false positive bands in SDS-page analysis of proteolytic digestion of a sample
    Patent number: 8569007
    Abstract: The present invention includes a method for reducing the appearance of false positive bands in SDS-PAGE analysis of proteolytic digestion, of a sample that comprises an immunoglobulin polypeptide, at pH 8.8.
    Type: Grant
    Filed: January 4, 2012
    Date of Patent: October 29, 2013
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Kimberly Margaret Louise May, Susan V. Cannon-Carlson, Brittany Charlotte Larkin, Collette Marie Cutler
  • HIGH-SENSITIVITY PROTEOLYSIS ASSAY
    Publication number: 20120103810
    Abstract: The present invention includes a highly sensitive method for detecting the presence of proteases in a sample which are present at very low levels.
    Type: Application
    Filed: January 4, 2012
    Publication date: May 3, 2012
    Inventors: Kimberly Margaret Louise May, Susan V. Cannon-Carlson, Brittany Charlotte Larkin, Collette Marie Cutler
  • Pegylated Interleukin-10
    Publication number: 20110064690
    Abstract: Interleukin-10 (IL-10) conjugated via a linker to one or more polyethylene glycol (PEG) molecules at a single amino acid residue of the IL-10, and a method for preparing the same, are provided. The method produces a stable mono-pegylated IL-10, which retains IL-10 activity, where pegylation is selective for the N-terminus on one subunit of IL-10 with little or no formation of monomeric IL-10. The method also provides a substantially homogenous population of mono-PEG-IL-10.
    Type: Application
    Filed: November 19, 2010
    Publication date: March 17, 2011
    Applicant: Schering Corporation
    Inventors: Seoju Lee, David C. Wylie, Susan V. Cannon-Carlson
  • PEGYLATED INTERLEUKIN-10
    Publication number: 20100297069
    Abstract: Interleukin-10 (IL-10) conjugated via a linker to one or more polyethylene glycol (PEG) molecules at a single amino acid residue of the IL-10, and a method for preparing the same, are provided. The method produces a stable mono-pegylated IL-10, which retains IL-10 activity, where pegylation is selective for the N-terminus on one subunit of IL-10 with little or no formation of monomeric IL-10. The method also provides a substantially homogenous population of mono-PEG-IL-10.
    Type: Application
    Filed: November 18, 2009
    Publication date: November 25, 2010
    Applicant: SCHERING CORPORATION
    Inventors: Seoju Lee, David C. Wylie, Susan V. Cannon-Carlson
  • High-sensitivity proteolysis assay
    Publication number: 20090294288
    Abstract: The present invention includes a highly sensitive method for detecting the presence of proteases in a sample which are present at very low levels.
    Type: Application
    Filed: December 11, 2007
    Publication date: December 3, 2009
    Inventors: Kimberly Margaret Louise May, Susan V. Cannon-Carlson, Brittany Charlotte Larkin, Collette Marie Cutler
  • PEGYLATED INTERLEUKIN-10
    Publication number: 20080317707
    Abstract: Interleukin-10 (IL-10) conjugated via a linker to one or more polyethylene glycol (PEG) molecules at a single amino acid residue of the IL-10, and a method for preparing the same, are provided. The method produces a stable mono-pegylated IL-10, which retains IL-10 activity, where pegylation is selective for the N-terminus on one subunit of IL-10 with little or no formation of monomeric IL-10. The method also provides a substantially homogenous population of mono-PEG-IL-10.
    Type: Application
    Filed: August 28, 2008
    Publication date: December 25, 2008
    Applicant: SCHERING CORPORATION
    Inventors: Seoju Lee, David C. Wylie, Susan V. Cannon-Carlson
  • Method for purifying adenoviruses
    Patent number: 7393631
    Abstract: Methods for purifying adenoviruses from a contaminated sample using a hydroxyapatite medium are provided. Sodium chloride concentrations present in buffers used throughout the method are at least 150 mM to prevent the adenovirus from irreversibly binding to the hydroxyapatite. Levels of contaminants and empty adenovirus capsids from samples purified by conventional purification techniques are further reduced to provide a highly pure adenovirus preparation.
    Type: Grant
    Filed: January 5, 2006
    Date of Patent: July 1, 2008
    Assignee: Schering Corporation
    Inventors: Susan V. Cannon-Carlson, Collette Cutler, Gary J. Vellekamp, Marcio Voloch
  • Pegylated interleukin-10
    Patent number: 7052686
    Abstract: Interleukin-10 (IL-10) conjugated via a linker to one or more polyethylene glycol (PEG) molecules at a single amino acid residue of the IL-10, and a method for preparing the same, are provided. The method produces a stable mono-pegylated IL-10, which retains IL-10 activity, where pegylation is selective for the N-terminus on one subunit of IL-10 with little or no formation of monomeric IL-10. The method also provides a substantially homogenous population of mono-PEG-IL-10.
    Type: Grant
    Filed: September 28, 2001
    Date of Patent: May 30, 2006
    Assignee: Schering Corporation
    Inventors: Seoju Lee, David C. Wylie, Susan V. Cannon-Carlson
  • Method for purifying adenoviruses
    Publication number: 20020064860
    Abstract: Methods for purifying adenoviruses from a contaminated sample using a hydroxyapatite medium are provided. Sodium chloride concentrations present in buffers used throughout the method are at least 150 mM to prevent the adenovirus from irreversibly binding to the hydroxyapatite. Levels of contaminants and empty adenovirus capsids from samples purified by conventional purification techniques are further reduced to provide a highly pure adenovirus preparation.
    Type: Application
    Filed: November 16, 2001
    Publication date: May 30, 2002
    Applicant: Schering Corporation
    Inventors: Susan V. Cannon-Carlson, Collette Cutler, Gary J. Vellekamp, Marcio Voloch
  • Pegylated interleukin-10
    Publication number: 20020044921
    Abstract: Interleukin-10 (IL-10) conjugated via a linker to one or more polyethylene glycol (PEG) molecules at a single amino acid residue of the IL-10, and a method for preparing the same, are provided. The method produces a stable mono-pegylated IL-10, which retains IL-10 activity, where pegylation is selective for the N-terminus on one subunit of IL-10 with little or no formation of monomeric IL-10. The method also provides a substantially homogenous population of mono-PEG-IL-10.
    Type: Application
    Filed: September 28, 2001
    Publication date: April 18, 2002
    Inventors: Seoju Lee, David C. Wylie, Susan V. Cannon-Carlson