Patents by Inventor Susan Watson

Susan Watson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240133088
    Abstract: The present device is a circular knitting machine, also known as a circular sock machine, designed to mostly be manufactured from polymers, such as plastics, or other materials that are typically lighter and have other physical properties, such as low hardness and tensile strength, compared to steel, from which such machines have historically been manufactured. The present design allows for the use of modern manufacturing techniques, such as 3-D printing in which a filament is often used comprising various types of polymers. The present device can also comprise a ribber apparatus, which is also designed to allow for most of its parts to be manufactured from polymers. However, in certain embodiments, some of the parts, such as needles, springs, and bolts can still be made from steel.
    Type: Application
    Filed: August 11, 2023
    Publication date: April 25, 2024
    Inventors: Denton Relland, Susan Relland, Steve Rewerts, Mary Watson
  • Patent number: 8343930
    Abstract: The present invention relates to a combination therapy method for treating gastrin-dependent tumors. The method comprises the immunization of a patient with an anti-gastrin 17 immunogenic composition in combination with the administration of chemotherapeutic agents such as 5-fluorouracil and leucovorin.
    Type: Grant
    Filed: January 25, 2010
    Date of Patent: January 1, 2013
    Assignee: Cancer Advances, Inc.
    Inventors: Philip C. Gevas, Stephen Grimes, Stephen L. Karr, Susan A. Watson, Dov Michaeli
  • Publication number: 20100129382
    Abstract: The present invention relates to a combination therapy method for treating gastrin-dependent tumors. The method comprises the immunization of a patient with an anti-gastrin 17 immunogenic composition in combination with the administration of chemotherapeutic agents such as 5-fluorouracil and leucovorin.
    Type: Application
    Filed: January 25, 2010
    Publication date: May 27, 2010
    Inventors: Philip C. Gevas, Stephen Grimes, Stephen L. Karr, Susan A. Watson, Dov Michaeli
  • Publication number: 20090191232
    Abstract: The present invention relates to a combination therapy method for treating gastrin-dependent tumors. The method comprises the immunization of a patient with an anti-gastrin 17 immunogenic composition in combination with the administration of chemotherapeutic agents such as 5-fluorouracil and leucovorin.
    Type: Application
    Filed: November 25, 2008
    Publication date: July 30, 2009
    Inventors: Philip C. Gevas, Stephen Grimes, Stephen L. Karr, Susan A. Watson, Dov Michaeli
  • Publication number: 20050187152
    Abstract: Serum-associated hypergastrinemia is treated by administration of gastrin active or passive immunization. An anti-gastrin immunogenic composition containing a gastrin G17 or G34 peptide fragment which is amino acid spacer-linked to an immunogenic carrier, is administered so as to effectively neutralize the circulating gastrin hormone, and moreover, inhibit autocrine activity by progastrin such as Gly-extended G17, and amidated G17, in patients with pernicious anemia. Moreover, the method includes administration of a therapeutically effective amount of anti-G17 or anti-G34 antibodies which may be in humanized form. Finally, the method provides ameliorating treatment of hypergastrinemic effects of proton pump inhibitors or H2 histamine receptor blocking agents or antagonists, in addition to treatment of hypergastrinemia caused by diseases such as pernicious anemia.
    Type: Application
    Filed: April 21, 2004
    Publication date: August 25, 2005
    Applicant: Aphton Corporation
    Inventors: Philip Gevas, Stephen Grimes, Stephen Karr, Dov Michaeli, Susan Watson
  • Publication number: 20050025770
    Abstract: A method of treating gastrointestinal cancers dependent on the prohormones amidated gastrin-17 and glycine extended G-17, comprising the administration to the patient of an anti-gastrin 17 immunogen which induces antibodies which bind and neutralize amidated and glycine-extended gastrin-17.
    Type: Application
    Filed: January 20, 2004
    Publication date: February 3, 2005
    Inventors: Philip Gevas, Stephen Karr, Stephen Grimes, Dov Michaeli, Susan Watson
  • Publication number: 20040259152
    Abstract: Described herein are methods that can be used for diagnosis of tissue remodeling, as well as tissue remodeling phenotypes. Also described herein are methods that can be used to screen candidate bioactive agents for the ability to modulate tissue remodeling. Additionally, molecular targets (genes and their products) for therapeutic intervention in disorders associated with tissue remodeling are described. Moreover, methods for using such molecular targets are described.
    Type: Application
    Filed: August 5, 2003
    Publication date: December 23, 2004
    Inventors: Richard Murray, Susan Watson, Stephen J. Weiss, Richard Glynne, Peter Hevezi
  • Patent number: 6794130
    Abstract: Nucleic acid is captured from a mixture of cellular debris produced by cell lysis by exposing the mixture to an electrode and applying a nucleic acid capturing voltage to the electrode which is then removed from the mixture carrying said nucleic acid. The nucleic acid is undamaged and can be amplified by PCR.
    Type: Grant
    Filed: March 11, 1999
    Date of Patent: September 21, 2004
    Assignee: Affymetrix, Inc.
    Inventors: Denise Vera Pollard-Knight, Sophie Elizabeth Victoria Martin, Susan Watson
  • Publication number: 20040009494
    Abstract: Described herein are methods that can be used for diagnosis of angiogenesis and angiogenic phenotypes. Also described herein are methods that can be used to screen candidate bioactive agents for the ability to modulate angiogenesis. Additionally, molecular targets (genes and their products) for therapeutic intervention in disorders associated with angiogenesis are described. Moreover, methods for using such molecular targets are described.
    Type: Application
    Filed: November 20, 2002
    Publication date: January 15, 2004
    Inventors: Richard Murray, Susan Watson, Stephen J. Weiss, Richard Glynne, Peter Hevezi
  • Publication number: 20040001842
    Abstract: The invention concerns immunogens, immunogenic compositions and method for the treatment of gastrin-dependent tumors. The immunogens comprise a gastrin receptor immunomimic peptide conjugated to an immunogenic carrier. The immunogens are capable of inducing antibodies in vivo which bind to the gastrin-receptor (GR) in gastrin responsive malignant or premalignant tumor, thereby preventing growth stimulating peptide hormones from binding to the receptors, and inhibiting tumor cell growth. The invention also comprises specific antibodies against the gastrin-receptor for passive immunization. Furthermore, the invention comprises cytotoxic molecule derivatized anti-GR antibodies. The invention also concerns diagnostic methods for detecting gastrin-dependent tumors in vivo or from a tissue biopsy using the antibodies of the invention. Active and passive immunization can be combined providing an immune response against GR, G17 and/or G17-Gly.
    Type: Application
    Filed: December 19, 2002
    Publication date: January 1, 2004
    Inventors: Dov Michaeli, Martyn Caplin, Susan A. Watson, Stephen Grimes
  • Publication number: 20030086941
    Abstract: The invention concerns immunogens, immunogenic compositions and method for the treatment of gastrin-dependent tumors. The immunogens comprise a peptide from the CCK-B/gastrin-receptor conjugated to a spacer and to an immunogenic carrier. The immunogens are capable of inducing antibodies in vivo which bind to the CCK-B/gastrin-receptor in tumor cells, thereby preventing growth stimulating peptide hormones from binding to the receptors, and inhibiting tumor cell growth. The immunogens also comprise antibodies against the CCK-B/gastrin-receptor for passive immunization. The invention also concerns diagnostic methods for detecting gastrin-dependent tumors in vivo or from a tissue biopsy using the antibodies of the invention.
    Type: Application
    Filed: September 4, 2002
    Publication date: May 8, 2003
    Inventors: Dov Michaeli, Martyn Caplin, Susan A. Watson, Stephen Grimes
  • Patent number: 6548066
    Abstract: The invention concerns immunogens, immunogenic compositions and method for the treatment of gastrin-dependent tumors. The immunogens comprise a peptide from the CCK-B/gastrin-receptor conjugated to a spacer and to an immunogenic carrier. The immunogens are capable of inducing antibodies in vivo which bind to the CCK-B/gastrin-receptor in tumor cells, thereby preventing growth stimulating peptide hormones from binding to the receptors, and inhibiting tumor cell growth. The immunogens also comprise antibodies against the CCK-B/gastrin-receptor for passive immunization. The invention also concerns diagnostic methods for detecting gastrin-dependent tumors in vivo or from a tissue biopsy using the antibodies of the invention.
    Type: Grant
    Filed: May 12, 1998
    Date of Patent: April 15, 2003
    Assignee: Aphton Corporation
    Inventors: Dov Michaeli, Martyn Caplin, Susan A. Watson, Stephen Grimes
  • Publication number: 20020019330
    Abstract: Described herein are methods that can be used for diagnosis of angiogenesis and angiogenic phenotypes. Also described herein are methods that can be used to screen candidate bioactive agents for the ability to modulate angiogenesis. Additionally, molecular targets (genes and their products) for therapeutic intervention in disorders associated with angiogenesis are described. Moreover, methods for using such molecular targets are described.
    Type: Application
    Filed: December 15, 2000
    Publication date: February 14, 2002
    Inventors: Richard Murray, Susan Watson, Stephen J. Weiss, Richard Glynne, Peter Hevezi
  • Publication number: 20020015970
    Abstract: Described herein are methods that can be used for diagnosis of angiogenesis and angiogenic phenotypes. Also described herein are methods that can be used to screen candidate bioactive agents for the ability to modulate angiogenesis. Additionally, molecular targets (genes and their products) for therapeutic intervention in disorders associated with angiogenesis are described. Moreover, methods for using such molecular targets are described.
    Type: Application
    Filed: December 15, 2000
    Publication date: February 7, 2002
    Inventors: Richard Murray, Susan Watson, Stephen J. Weiss, Richard Glynne, Peter Hevezi
  • Publication number: 20010008762
    Abstract: Nucleic acid is captured from a mixture of cellular debris produced by cell lysis by exposing the mixture to an electrode and applying a nucleic acid capturing voltage to the electrode which is then removed from the mixture carrying said nucleic acid. The nucleic acid is undamaged and can be amplified by PCR.
    Type: Application
    Filed: March 11, 1999
    Publication date: July 19, 2001
    Inventors: DENISE VERA POLLARD-KNIGHT, SOPHIE ELIZABETH VICTORIA MARTIN, SUSAN WATSON