Patents by Inventor Susan X. Qian

Susan X. Qian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Extracellular matrix coated surface for culturing cells
    Patent number: 8802435
    Abstract: A cell culture product is provided for propagating embryonic stem cells, and maintaining their self-renewal and pluripotency characteristics for extended periods of time in culture. The cell culturing product includes a substrate; and a coating thereon deposited from a coating solution. The coating solution includes a mixture of extracellular matrix proteins and an aqueous solvent, wherein the total protein concentration in the coating solution is about 10 ?g/ml to about 1 mg/ml.
    Type: Grant
    Filed: July 12, 2012
    Date of Patent: August 12, 2014
    Assignee: Corning Incorporated
    Inventors: Susan X. Qian, Suparna Sanyal
  • Cell culture surfaces having hydrogel supported proteins
    Patent number: 8574906
    Abstract: A method is disclosed herein for treating a polymeric surface to define an improved cell culture surface. The method includes the steps of: coating the polymeric surface with a hydrogel; and attaching proteins to the hydrogel-coated surface. Advantageously, a method is provided which consistently produces improved cell culture surfaces that generally avoid bare spots and possible undesired protein absorption or cell differentiation.
    Type: Grant
    Filed: August 8, 2008
    Date of Patent: November 5, 2013
    Assignee: Corning Incorporated
    Inventors: Xiaoxi (Kevin) Chen, Susan X. Qian
  • EXTRACELLULAR MATRIX COATED SURFACE FOR CULTURING CELLS
    Publication number: 20120282691
    Abstract: A cell culture product is provided for propagating embryonic stem cells, and maintaining their self-renewal and pluripotency characteristics for extended periods of time in culture. The cell culturing product includes a substrate; and a coating thereon deposited from a coating solution. The coating solution includes a mixture of extracellular matrix proteins and an aqueous solvent, wherein the total protein concentration in the coating solution is about 10 ?g/m1 to about 1 mg/ml.
    Type: Application
    Filed: July 12, 2012
    Publication date: November 8, 2012
    Applicant: BECTON DICKINSON AND COMPANY
    Inventors: Susan X. Qian, Suparna Sanyal
  • Extracellular matrix coated surface for culturing cells
    Patent number: 8241908
    Abstract: A cell culture product is provided for propagating embryonic stem cells, and maintaining their self-renewal and pluripotency characteristics for extended periods of time in culture. The cell culturing, product includes a substrate; and a coating thereon deposited, from a coating solution. The coating solution includes a mixture of extracellular matrix proteins and an aqueous solvent, wherein the total protein concentration in the coating solution is about 10 ?g/ml to about 1 mg/ml.
    Type: Grant
    Filed: May 11, 2007
    Date of Patent: August 14, 2012
    Assignee: Becton, Dickinson and Company
    Inventors: Susan X. Qian, Suparna Sanyal
  • Immunocytokine Sequences and Uses Thereof
    Publication number: 20100210831
    Abstract: The invention provides a family of antibodies that specifically bind the human cell surface glycosphingolipid GD2. The antibodies comprise modified variable regions, more specially, modified framework regions, which reduce their immunogenicity when administered to a human. The antibodies may be coupled to a therapeutic agent and used in the treatment of cancer.
    Type: Application
    Filed: April 27, 2010
    Publication date: August 19, 2010
    Applicant: MERCK PATENT GMBH
    Inventors: STEPHEN D. GILLIES, KIN-MING LO, SUSAN X. QIAN
  • Immunocytokine sequences and uses thereof
    Patent number: 7767405
    Abstract: The invention provides a family of antibodies that specifically bind the human cell surface glycosphingolipid GD2. The antibodies comprise modified variable regions, more specially, modified framework regions, which reduce their immunogenicity when administered to a human. The antibodies may be coupled to a therapeutic agent and used in the treatment of cancer.
    Type: Grant
    Filed: November 15, 2006
    Date of Patent: August 3, 2010
    Assignee: Merck Patent GmbH
    Inventors: Stephen D. Gillies, Kin-Ming Lo, Susan X. Qian
  • RECOMBINANT TUMOR SPECIFIC ANTIBODY AND USE THEREOF
    Publication number: 20100174056
    Abstract: The invention provides a family of antibodies that specifically bind the human epithelial cell adhesion molecule. The antibodies comprise modified variable regions, more specially, modified framework regions, which reduce their immunogenicity when administered to a human. The antibodies, when coupled to the appropriate moiety, may be used in the diagnosis, prognosis and treatment of cancer.
    Type: Application
    Filed: August 29, 2008
    Publication date: July 8, 2010
    Applicant: Merck Patent GmbH
    Inventors: Stephen D. Gillies, Kin-Ming Lo, Susan X. Qian
  • CELL CULTURE SURFACES HAVING HYDROGEL SUPPORTED PROTEINS
    Publication number: 20090043079
    Abstract: A method is disclosed herein for treating a polymeric surface to define an improved cell culture surface. The method includes the steps of: coating the polymeric surface with a hydrogel; and attaching proteins to the hydrogel-coated surface. Advantageously, a method is provided which consistently produces improved cell culture surfaces that generally avoid bare spots and possible undesired protein absorption or cell differentiation.
    Type: Application
    Filed: August 8, 2008
    Publication date: February 12, 2009
    Applicant: Becton, Dickinson and Company
    Inventors: Xiaoxi (Kevin) Chen, Susan X. Qian
  • Immunocytokine sequences and uses thereof
    Patent number: 7169904
    Abstract: The invention provides a family of antibodies that specifically bind the human cell surface glycosphingolipid GD2. The antibodies comprise modified variable regions, more specially, modified framework regions, which reduce their immunogenicity when administered to a human. The antibodies may be coupled to a therapeutic agent and used in the treatment of cancer.
    Type: Grant
    Filed: December 16, 2003
    Date of Patent: January 30, 2007
    Assignee: EMD Lexigen Research Center Corp.
    Inventors: Stephen D. Gillies, Kin-Ming Lo, Susan X. Qian
  • Recombinant tumor specific antibody and use thereof
    Patent number: 6969517
    Abstract: The invention provides a family of antibodies that specifically bind the human epithelial cell adhesion molecule. The antibodies comprise modified variable regions, more specially, modified framework regions, which reduce their immunogenicity when administered to a human. The antibodies, when coupled to the appropriate moiety, may be used in the diagnosis, prognosis and treatment of cancer.
    Type: Grant
    Filed: May 3, 2002
    Date of Patent: November 29, 2005
    Assignee: EMD Lexigen Research Center Corp.
    Inventors: Stephen D. Gillies, Kin-Ming Lo, Susan X. Qian
  • Recombinant tumor specific antibody and use thereof
    Publication number: 20030157054
    Abstract: The invention provides a family of antibodies that specifically bind the human epithelial cell adhesion molecule. The antibodies comprise modified variable regions, more specially, modified framework regions, which reduce their immunogenicity when administered to a human. The antibodies, when coupled to the appropriate moiety, may be used in the diagnosis, prognosis and treatment of cancer.
    Type: Application
    Filed: May 3, 2002
    Publication date: August 21, 2003
    Applicant: Lexigen Pharmaceuticals Corp.
    Inventors: Stephen D. Gillies, Kin-Ming Lo, Susan X. Qian