Patents by Inventor Susana CABALLERO ROMÁN

Susana CABALLERO ROMÁN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bacterial strain producing 2,3-butanediol and other metabolites
    Patent number: 11111474
    Abstract: The present invention provides a modified strain of the bacterium Lactococcus lactis obtainable by a method that comprises a step of fusion of two protoplasts from two Lactococcus lactis parental strains which, compared to the wild type strain of Lactococcus lactis from which they derive, show: (a) an increased ability to produce acetoin and/or 2,3-butanediol (2,3-BDO), and (b) a decreased ability to produce lactic acid, when cultured under aerobic conditions, and wherein the modified strain of Lactococcus lactis has an increased ability to produce 2,3-BDO of at least 20 times the amount produced by the wild type strain, an increased ability to produce acetoin of at least 20 times the amount produced by the wild type strain and a decreased ability to produce lactic acid of at least 10 times the amount produced by the wild type strain, when cultured under aerobic conditions. Also provided are methods to produce acetoin and 2,3-BDO.
    Type: Grant
    Filed: July 18, 2017
    Date of Patent: September 7, 2021
    Assignee: FUNDACION TECNALIA RESEARCH & INNOVATION
    Inventors: Tomás Roncal Martínez, Susana Caballero Román, María Del Mar Díaz De Guereñu Zabarte, Inés Rincón Arroyo, Soraya Prieto Fernández, José Ramón Ochoa Gómez
  • BACTERIAL STRAIN PRODUCING 2,3-BUTANEDIOL AND OTHER METABOLITES
    Publication number: 20190233907
    Abstract: The present invention provides a modified strain of the bacterium Lactococcus lactis obtainable by a method that comprises a step of fusion of two protoplasts from two Lactococcus lactis parental strains which, compared to the wild type strain of Lactococcus lactis from which they derive, show: (a) an increased ability to produce acetoin and/or 2,3-butanediol (2,3-BDO), and (b) a decreased ability to produce lactic acid, when cultured under aerobic conditions, and wherein the modified strain of Lactococcus lactis has an increased ability to produce 2,3-BDO of at least 20 times the amount produced by the wild type strain, an increased ability to produce acetoin of at least 20 times the amount produced by the wild type strain and a decreased ability to produce lactic acid of at least 10 times the amount produced by the wild type strain, when cultured under aerobic conditions. Also provided are methods to produce acetoin and 2,3-BDO.
    Type: Application
    Filed: July 18, 2017
    Publication date: August 1, 2019
    Inventors: Tomás RONCAL MARTÍNEZ, Susana CABALLERO ROMÁN, María Del Mar DÍAZ DE GUEREÑU ZABARTE, Inés RINCÓN ARROYO, Soraya PRIETO FERNÁNDEZ, José Ramón OCHOA GÓMEZ