Patents by Inventor Susana Marto

Susana Marto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline minocycline base and processes for its preparation
    Patent number: 9416097
    Abstract: The invention provides crystalline minocycline base. In particular, three crystalline polymorphic forms, designated Form I, Form II and Form III, of minocycline base are provided. These are characterized by XRD and IR data. Processes for preparing the new polymorphic forms are also provided. For example, Form I is prepared by dissolving and/or suspending amorphous minocycline base in an organic solvent chosen from ethers followed by crystallization from the mixture.
    Type: Grant
    Filed: August 30, 2012
    Date of Patent: August 16, 2016
    Assignee: Hovione Scientia Limited
    Inventors: Zita Mendes, Jose Rafael Antunes, Susana Marto, William Heggie
  • Crystalline Minocycline Base and Processes for its Preparation
    Publication number: 20130030195
    Abstract: The invention provides crystalline minocycline base. In particular, three crystalline polymorphic forms, designated Form I, Form II and Form III, of minocycline base are provided. These are characterised by XRD and IR data. Processes for preparing the new polymorphic forms are also provided. For example, Form I is prepared by dissolving and/or suspending amorphous minocycline base in an organic solvent chosen from ethers followed by crystallisation from the mixture.
    Type: Application
    Filed: August 30, 2012
    Publication date: January 31, 2013
    Inventors: Zita Mendes, Jose Rafael Antunes, Susana Marto, William Heggie
  • Crystalline minocycline base and processes for its preparation
    Patent number: 8258327
    Abstract: The invention provides crystalline minocycline base. In particular, three crystalline polymorphic forms, designated Form I, Form II and Form III, of minocycline base are provided. These are characterized by XRD and IR data. Processes for preparing the new polymorphic forms are also provided. For example, Form I is prepared by dissolving and/or suspending amorphous minocycline base in an organic solvent chosen from ethers followed by crystallization from the mixture.
    Type: Grant
    Filed: February 22, 2008
    Date of Patent: September 4, 2012
    Assignee: Hovlone Inter Limited
    Inventors: Susana Marto, William Heggie, Zita Mendes, Jose Rafael Antunes
  • Crystalline Minocycline Base and Processes for its Preparation
    Publication number: 20100286417
    Abstract: The invention provides crystalline minocycline base. In particular, three crystalline polymorphic forms, designated Form I, Form II and Form III, of minocycline base are provided. These are characterised by XRD and IR data. Processes for preparing the new polymorphic forms are also provided. For example, Form I is prepared by dissolving and/or suspending amorphous minocycline base in an organic solvent chosen from ethers followed by crystallisation from the mixture.
    Type: Application
    Filed: February 22, 2008
    Publication date: November 11, 2010
    Applicant: HOVIONE INTER LIMITED
    Inventors: Zita Mendes, Jose Rafael Antunes, Susana Marto, William Heggie
  • Process for the manufacture of iohexol
    Patent number: 7541494
    Abstract: A process for the production of iohexol comprises alkylating 5-Acetamido-N,N?-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide using 2(2-methoxy-ethoxy)-ethanol as solvent in the presence of a base, and optionally isolating crude iohexol from the reaction mixture. Preferably, the alkylating agent is 1-chloro-2,3 propanediol and the base is an alkali metal hydroxide such as sodium hydroxide or potassium hydroxide.
    Type: Grant
    Filed: March 3, 2006
    Date of Patent: June 2, 2009
    Assignee: Hovione Inter Ltd.
    Inventors: José Galindro, Susana Marto, João Bandarra, William Heggie
  • Process for the manufacture of iohexol
    Publication number: 20090048463
    Abstract: A process for the production of iohexol comprises alkylating 5-Acetamido-N,N?-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide using 2(2-methoxy-ethoxy)-ethanol as solvent in the presence of a base, and optionally isolating crude iohexol from the reaction mixture. Preferably, the alkylating agent is 1-chloro-2,3 propanediol and the base is an alkali metal hydroxide such as sodium hydroxide or potassium hydroxide.
    Type: Application
    Filed: March 3, 2006
    Publication date: February 19, 2009
    Inventors: Jose Galindro, Susana Marto, Joao Bandarra, William Heggie