Patents by Inventor Susana Yenes Mínguez

Susana Yenes Mínguez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Quinoline and isoquinoline derivatives for treating pain and pain related conditions
    Patent number: 10941138
    Abstract: The present invention relates to new compounds of formula (I): showing great affinity and activity towards the subunit ?2? of voltage-gated calcium channels (VGCC), especially the ?2?-1 subunit of voltage-gated calcium channels or dual activity towards subunit ?2? of voltage-gated calcium channels (VGCC), especially the ?2?-1 subunit of voltage-gated calcium channels, and the noradrenaline transporter (NET).
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: March 9, 2021
    Assignee: ESTEVE PHARMACEUTICALS, S.A.
    Inventors: Carmen Almansa-Rosales, Susana Yenes-Mínguez, Marina Virgili-Bernado, Monica Alonso-Xalma
  • (HETERO)ARYLALKYLAMINO-PYRAZOLOPYRIDAZINE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN
    Publication number: 20200199127
    Abstract: The present invention relates to (hetero)arylalkylamino-pyrazolopyridazine derivatives having dual pharmacological activity towards both the ?2? subunit, in particular the ?2?-1 subunit, of the voltage-gated calcium channel and the Noradrenaline transporter (NET), to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.
    Type: Application
    Filed: May 29, 2018
    Publication date: June 25, 2020
    Inventors: Susana YENES-MINGUEZ, Ariadna FERNANDEZ-DONIS, Carmen ALMANSA-ROSALES
  • COMPOUNDS HAVING MULTIMODAL ACTIVITY AGAINST PAIN
    Publication number: 20200123115
    Abstract: The present invention relates to a compound of formula (I): wherein the meanings for the various substituents are as disclosed in the description, having dual pharmacological activity towards both the ?2? subunit, in particular the ?2?-1 subunit, of the voltage-gated calcium channel and the NET receptor, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.
    Type: Application
    Filed: June 25, 2018
    Publication date: April 23, 2020
    Inventors: Susana YENES-MINGUEZ, Carmen ALMANSA-ROSALES
  • NEW QUINOLINE AND ISOQUINOLINE DERIVATIVES FOR TREATING PAIN AND PAIN RELATED CONDITIONS
    Publication number: 20200087291
    Abstract: The present invention relates to new compounds of formula (I): showing great affinity and activity towards the subunit ?2? of voltage-gated calcium channels (VGCC), especially the ?2?-1 subunit of voltage-gated calcium channels or dual activity towards subunit ?2? of voltage-gated calcium channels (VGCC), especially the ?2?-1 subunit of voltage-gated calcium channels, and the noradrenaline transporter (NET).
    Type: Application
    Filed: December 20, 2017
    Publication date: March 19, 2020
    Inventors: Carmen ALMANSA-ROSALES, Susana YENES-MÍNGUEZ, Marina VIRGILI-BERNADO, Monica ALONSO-XALMA
  • SUBSTITUTED PYRROLIDINYL AND PIPERIDINYL PYRAZOLOPYRIDAZINE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN
    Publication number: 20200062767
    Abstract: The present invention relates to substituted pyrrolidinyl and piperidinyl pyrazolopyridazine derivatives having dual pharmacological activity towards both the ?2? subunit, in particular the ?2??1 subunit, of the voltage-gated calcium channel and the Noradrenaline transporter (NET), to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.
    Type: Application
    Filed: May 29, 2018
    Publication date: February 27, 2020
    Inventors: Carmen ALMANSA-ROSALES, José-Luís DÍAZ-FERNÁNDEZ, Ariadna FERNANDEZ-DONIS, Susana YENES-MINGUEZ
  • PYRAZOLE DERIVATIVES HAVING ACTIVITY AGAINST PAIN
    Publication number: 20200002283
    Abstract: The present invention relates to pyrazole derivatives having pharmacological activity towards the ?2? subunit, in particular the ?2?-1 subunit, of the voltage-gated calcium channel, in particular having dual pharmacological activity towards both the ?2? subunit, in particular the ?2?-1 subunit, of the voltage-gated calcium channel and the ?-opioid receptor. The present invention also relates to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.
    Type: Application
    Filed: June 26, 2017
    Publication date: January 2, 2020
    Inventors: Carmen ALMANSA-ROSALES, Susana YENES-MÍNGUEZ, José-Luis DÍAZ-FERNÁNDEZ, Antonio David RODRIGUEZ-GARRIDO
  • Bicyclic tetrahydropyrrole compounds
    Patent number: 9271959
    Abstract: The present invention relates to substituted bicyclic tetrahydropyrrole compounds of general formula (I), methods for their preparation, medicaments comprising these compounds as well their use in the manufacture of a medicament for the treatment of humans and animals.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: March 1, 2016
    Assignee: LABORATORIOS DEL DR. ESTEVE, S.A.
    Inventors: Miguel Angel Pericas-Brondo, Antonio Torrens-Jover, Susana Yenes-Minguez, Felix Cuevas Cordobes, Carmen Garcia Granda
  • Bicyclic tetrahydropyrrole compounds
    Patent number: 8372990
    Abstract: The present invention relates to substituted bicyclic tetrahydropyrrole compounds of general formula (I), methods for their preparation, medicaments comprising these compounds as well their use in the manufacture of a medicament for the treatment of humans and animals.
    Type: Grant
    Filed: April 30, 2007
    Date of Patent: February 12, 2013
    Assignee: Laboratorios Del Dr. Esteve S.A.
    Inventors: Miguel Angel Pericas-Brondo, Antonio Torrens-Jover, Susana Yenes-Minguez, Félix Cuevas Cordobés, Carmen Garcia Granda
  • Tricyclic triazolic compounds
    Patent number: 8362011
    Abstract: The present invention relates to new tricyclic triazolic compounds having a high affinity for sigma-1 receptor as well as to the process for the preparation thereof, to composition comprising them and to their use as medicaments according to compounds of formula (I), Wherein R1 and R2 are as defined in the description.
    Type: Grant
    Filed: December 5, 2008
    Date of Patent: January 29, 2013
    Assignee: Laboratories del Dr. Esteve, S.A.
    Inventors: Miguel Angel Pericas-Brondo, Antoni Torrens-Jover, Félix Cuevas-Cordobes, Susana Yenes-Minguez
  • Bicyclic tetrahydropyrrole compounds
    Patent number: 8299113
    Abstract: The present invention relates to substituted bicyclic tetrahydropyrrole compounds of general formula (I), methods for their preparation, medicaments comprising these compounds as well their use in the manufacture of a medicament for the treatment of humans and animals.
    Type: Grant
    Filed: April 30, 2007
    Date of Patent: October 30, 2012
    Assignee: Laboratorios del Dr. Esteve, S.A.
    Inventors: Miguel Angel Pericas-Brondo, Antonio Torrens-Jover, Susana Yenes-Minguez, Félix Cuevas Cordobes, Carmen Garcia Granda
  • 5-HTreceptor antagonists
    Patent number: 8188115
    Abstract: The invention relates to compounds having pharmacological activity towards the 5-HT7 receptor, and more particularly to some tetrahydroisoquinoline substituted sulfonamide compounds, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which 5-HT is involved, such as CNS disorders.
    Type: Grant
    Filed: August 18, 2005
    Date of Patent: May 29, 2012
    Assignee: Laboratorios Del Dr. Esteve, S.A.
    Inventors: Antoni Torrens Jover, Josep Mas Prio, Susana Yenes Minguez, Mónica Garcia Lopez, Alberto Dordal Zueras, Luz Romero Alonso, Helmut Henrich Buschmann
  • 5-HT7 receptor antagonists
    Patent number: 8148397
    Abstract: The invention relates to compounds having pharmacological activity towards the 5-HT7 receptor, and more particularly to some tetrahydroisoquinoline propyl sulfonamide compounds, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which 5-HT is involved, such as CNS disorders.
    Type: Grant
    Filed: August 18, 2005
    Date of Patent: April 3, 2012
    Assignee: Laboratorios Del Dr. Esteve, S.A.
    Inventors: Antoni Torrens Jover, Josep Mas Prio, Susana Yenes Minguez, Monica Garcia Lopez, Alberto Dordal Zueras, Luz Romero Alonso, Helmut Henrich Buschmann
  • Indoline-substituted pyrazoline derivatives, their preparation and use as medicaments
    Patent number: 8106085
    Abstract: The present invention relates to indoline-substituted pyrazoline compounds of formula (I), methods for their preparation, medicaments comprising these compounds as well as their use for the preparation of a medicament for the treatment of humans and animals.
    Type: Grant
    Filed: July 17, 2006
    Date of Patent: January 31, 2012
    Assignee: Laboratorios Del Dr. Esteve, S.A.
    Inventors: Antonio Torrens Jover, Susana Yenes Minguez
  • Sulfonamide substituted pyrazoline compounds, their preparation and use as CB1 modulators
    Patent number: 8044053
    Abstract: The present invention relates to substituted pyrazoline compounds of general formula (I), methods for their preparation, medicaments comprising these compounds as well as their use for the preparation of a medicament for the treatment of humans and animals.
    Type: Grant
    Filed: October 10, 2007
    Date of Patent: October 25, 2011
    Assignee: Laboratories del Dr. Esteve, S.A.
    Inventors: Helmut Buschmann, Antonio Torrens-Jover, Josef Mas-Prio, Susana Yenes-Minguez
  • Cycloalkane-substituted pyrazoline derivatives, their preparation and use as medicaments
    Patent number: 7994200
    Abstract: The present invention relates to Cycloalkane-substituted substituted pyrazoline compounds of formula (I), methods for their preparation, medicaments comprising these compounds as well as their use for the preparation of a medicament for the treatment of humans and animals.
    Type: Grant
    Filed: July 17, 2006
    Date of Patent: August 9, 2011
    Assignee: Laboratorios del Dr. Esteve, S.A.
    Inventors: Antonio Torrens Jover, Susana Yenes Minguez
  • 5-HT7 receptor antagonists
    Patent number: 7928121
    Abstract: The invention relates to compounds having pharmacological activity towards the 5-HT7 receptor, and more particularly to some tetrahydroisoquinoline substituted sulfonamide compounds, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which 5-HT is involved, such as CNS disorders.
    Type: Grant
    Filed: December 27, 2005
    Date of Patent: April 19, 2011
    Assignee: Laboratorios Del Dr. Esteve, S.A.
    Inventors: Antoni Torrens Jover, Susana Yenes Mínguez, Josep Mas Prió, Luz Romero Alonso, Alberto Dordal Zueras, Helmut Henrich Buschmann
  • 4-METHYL-4,5-DIHYDRO-1H-PYRAZOLE-3-CARBOXAMIDE USEFUL AS A CANNABINOID CB1 NEUTRAL ANTAGONIST
    Publication number: 20110028517
    Abstract: The present invention relates to 4-methyl-4,5-dihydro-1H-pyrazole-3-carboxamide, and pharmaceutically acceptable salts and solvates thereof. It further concerns pharmaceutical compositions comprising this compound as active ingredient as well as processes and intermediates for preparing this compound and compositions. The referred compound is a cannabinoid CB1 neutral antagonist useful in the prophylaxis and treatment of food intake disorders.
    Type: Application
    Filed: April 7, 2009
    Publication date: February 3, 2011
    Applicant: LABORATORIOS DEL DR. ESTEVE, S.A.
    Inventors: Jose Miguel Vela Hernandez, Susana Yenes Minguez
  • TRICYCLIC TRIAZOLIC COMPOUNDS
    Publication number: 20100298309
    Abstract: The present invention relates to new tricyclic triazolic compounds having a high affinity for sigma-1 receptor as well as to the process for the preparation thereof, to composition comprising them and to their use as medicaments according to compounds of formula (I), Wherein R1 and R2 are as defined in the description.
    Type: Application
    Filed: December 5, 2008
    Publication date: November 25, 2010
    Inventors: Miguel Angel Pericas-Brondo, Antoni Torrens-Jover, Félix Cuevas-Cordobes, Susana Yenes-Minguez
  • Prodrugs of pyrazoline compounds, their preparation and use as medicaments
    Patent number: 7829581
    Abstract: The present invention relates to prodrugs of pyrazoline compounds of formula I, methods for their preparation, medicaments comprising these compounds as well as their use for the preparation of a medicament for the treatment of humans and animals.
    Type: Grant
    Filed: July 17, 2006
    Date of Patent: November 9, 2010
    Assignee: Laboratorios Del Dr. Esteve, S.A.
    Inventors: Antonio Torrens Jover, Susana Yenes-Minguez
  • SULFONAMIDE SUBSTITUTED PYRAZOLINE COMPOUNDS, THEIR PREPARATION AND USE AS CB1 MODULATORS
    Publication number: 20100184772
    Abstract: The present invention relates to substituted pyrazoline compounds of general formula (I), methods for their preparation, medicaments comprising these compounds as well as their use for the preparation of a medicament for the treatment of humans and animals.
    Type: Application
    Filed: October 10, 2007
    Publication date: July 22, 2010
    Applicant: LABORATORIOS DEL DR. ESTEVE, S.A.
    Inventors: Helmut H. Buschmann, Antonio Torrens-Jover, Josef Mas-Prio, Susana Yenes-Minguez