Patents by Inventor Susanne Grafe

Susanne Grafe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220305096
    Abstract: The present invention relates to methods for reducing facial lines or wrinkles of the skin or of removing facial asymmetries by administering a composition containing the neurotoxic component of a Clostridium botulinum toxin complex, wherein the composition may be devoid of any other protein of the Clostridium botulinum toxin complex and wherein the composition is administered at short intervals and/or in high doses.
    Type: Application
    Filed: June 7, 2022
    Publication date: September 29, 2022
    Inventors: Matthias Marx, Susanne Grafe, Reiner Benecke, Dirk Dressler
  • Publication number: 20220305095
    Abstract: The present invention relates to methods for treating diseases and disorders by administering a composition containing the neurotoxic component of a Clostridium botulinum toxin complex, wherein the composition may be devoid of any other protein of the Clostridium botulinum toxin complex and wherein the composition is administered at short intervals and/or in high doses.
    Type: Application
    Filed: June 7, 2022
    Publication date: September 29, 2022
    Inventors: Matthias MARX, Susanne GRAFE, Reiner BENECKE, Dirk DRESSLER
  • Patent number: 11382960
    Abstract: The present invention relates to methods for treating diseases and disorders by administering a composition containing the neurotoxic component of a Clostridium botulinum toxin complex, wherein the composition is devoid of any other protein of the Clostridium botulinum toxin complex and wherein the composition is administered at short intervals and/or in high doses.
    Type: Grant
    Filed: September 1, 2020
    Date of Patent: July 12, 2022
    Assignee: MERZ PHARMA GmbH & CO. KGaA
    Inventors: Matthias Marx, Susanne Grafe, Reiner Benecke, Dirk Dressler
  • Publication number: 20200397874
    Abstract: The present invention relates to methods for treating diseases and disorders by administering a composition containing the neurotoxic component of a Clostridium botulinum toxin complex, wherein the composition is devoid of any other protein of the Clostridium botulinum toxin complex and wherein the composition is administered at short intervals and/or in high doses.
    Type: Application
    Filed: September 1, 2020
    Publication date: December 24, 2020
    Inventors: Matthias MARX, Susanne Grafe, Reiner Benecke, Dirk Dressler
  • Patent number: 10792344
    Abstract: The present invention relates to methods for treating diseases and disorders by administering a composition containing the neurotoxic component of a Clostridium botulinum toxin complex, wherein the composition is devoid of any other protein of the Clostridium botulinum toxin complex and wherein the composition is administered at short intervals and/or in high doses.
    Type: Grant
    Filed: January 11, 2017
    Date of Patent: October 6, 2020
    Assignee: MERZ PHARMA GmbH & CO. KGaA
    Inventors: Matthias Marx, Susanne Grafe, Reiner Benecke, Dirk Dressler
  • Publication number: 20190142912
    Abstract: The present invention relates to methods for treating diseases and disorders by administering a composition containing the neurotoxic component of a Clostridium botulinum toxin complex, wherein the composition is devoid of any other protein of the Clostridium botulinum toxin complex and wherein the composition is administered at short intervals and/or in high doses.
    Type: Application
    Filed: January 11, 2017
    Publication date: May 16, 2019
    Inventors: Matthias MARX, Susanne GRAFE, Reiner BENECKE, Dirk DRESSLER
  • Publication number: 20180193434
    Abstract: The present invention relates to methods for treating diseases and disorders by administering a composition containing the neurotoxic component of a Clostridium botulinum toxin complex, wherein the composition is devoid of any other protein of the Clostridium botulinum toxin complex and wherein the composition is administered at short intervals and/or in high doses.
    Type: Application
    Filed: January 11, 2017
    Publication date: July 12, 2018
    Inventors: Matthias MARX, Susanne GRAFE, Reiner BENECKE, Dirk DRESSLER
  • Publication number: 20170189500
    Abstract: This invention relates to novel uses of recombinant clostridial neurotoxins exhibiting decreased duration of effect, in particular uses for the treatment of patients having experienced muscle-related disorders and/or injuries.
    Type: Application
    Filed: June 12, 2015
    Publication date: July 6, 2017
    Inventors: Klaus FINK, Susanne GRAFE, Imke SCHULTZ, Susanna ROLL, Deryck JORDAN
  • Publication number: 20170128551
    Abstract: This invention relates to novel uses of recombinant clostridial neurotoxins exhibiting decreased duration of effect, in particular uses for the treatment of patients suffering from a limited range of muscle extension, in particular from flexion contracture, in particular flexion contracture of the knee, and more particularly uses for the treatment of such patients having experienced a total knee arthroplasty.
    Type: Application
    Filed: June 12, 2015
    Publication date: May 11, 2017
    Inventors: Klaus FINK, Susanne GRAFE, Imke SCHULTZ, Susanna ROLL
  • Publication number: 20170119863
    Abstract: This invention relates to novel uses of recombinant clostridial neurotoxins exhibiting decreased duration of effect, in particular uses for the treatment of patients having experienced tendon-related disorders and/or injuries.
    Type: Application
    Filed: June 12, 2015
    Publication date: May 4, 2017
    Inventors: Klaus FINK, Susanne GRAFE, Imke SCHULTZ, Susanna ROLL
  • Publication number: 20170112907
    Abstract: This invention relates to novel uses of recombinant clostridial neurotoxins exhibiting decreased duration of effect, in particular uses for the treatment of different forms of back pain, in particular recurrent low back pain.
    Type: Application
    Filed: June 12, 2015
    Publication date: April 27, 2017
    Inventors: KLAUS FINK, SUSANNE GRAFE, IMKE SCHULTZ
  • Patent number: 9572871
    Abstract: The present invention relates to methods for treating diseases and disorders by administering a composition containing the neurotoxic component of a Clostridium botulinum toxin complex, wherein the composition is devoid of any other protein of the Clostridium botulinum toxin complex and wherein the composition is administered at short intervals and/or in high doses.
    Type: Grant
    Filed: June 25, 2015
    Date of Patent: February 21, 2017
    Assignee: MERZ PHARMA GmbH & Co. KGaA
    Inventors: Matthias Marx, Susanne Grafe, Reiner Benecke, Dirk Dressler
  • Publication number: 20150290303
    Abstract: The present invention relates to methods for treating diseases and disorders by administering a composition containing the neurotoxic component of a Clostridium botulinum toxin complex, wherein the composition is devoid of any other protein of the Clostridium botulinum toxin complex and wherein the composition is administered at short intervals and/or in high doses.
    Type: Application
    Filed: June 25, 2015
    Publication date: October 15, 2015
    Inventors: Matthias MARX, Susanne GRAFE, Reiner BENECKE, Dirk DRESSLER
  • Patent number: 9095523
    Abstract: The present invention relates to methods for treating diseases and disorders by administering a composition containing the neurotoxic component of a Clostridium botulinum toxin complex, wherein the composition is devoid of any other protein of the Clostridium botulinum toxin complex and wherein the composition is administered at short intervals and/or in high doses.
    Type: Grant
    Filed: September 13, 2013
    Date of Patent: August 4, 2015
    Assignee: MERZ PHARMA GmbH & CO. KGaA
    Inventors: Matthias Marx, Susanne Grafe, Reiner Benecke, Dirk Dressler
  • Publication number: 20140010803
    Abstract: The present invention relates to methods for treating diseases and disorders by administering a composition containing the neurotoxic component of a Clostridium botulinum toxin complex, wherein the composition is devoid of any other protein of the Clostridium botulinum toxin complex and wherein the composition is administered at short intervals and/or in high doses.
    Type: Application
    Filed: September 13, 2013
    Publication date: January 9, 2014
    Applicant: MERZ PHARMA GmbH & CO. KGaA
    Inventors: Matthias Marx, Susanne Grafe, Reiner Benecke, Dirk Dressler
  • Patent number: 8557255
    Abstract: The present invention relates to methods for treating diseases and disorders by administering a composition containing the neurotoxic component of a Clostridium botulinum toxin complex, wherein the composition is devoid of any other protein of the Clostridium botulinum toxin complex and wherein the composition is administered at short intervals and/or in high doses.
    Type: Grant
    Filed: June 29, 2007
    Date of Patent: October 15, 2013
    Assignee: Merz Pharma GmbH & Co. KGaA
    Inventors: Matthias Marx, Susanne Grafe, Reiner Benecke, Dirk Dressler
  • Publication number: 20080279896
    Abstract: The present invention relates to a method of treating a movement disorder in a patient, the method comprising administering a medicament comprising an effective amount of chemodenervating agent to the patient, wherein the patient is subjected to a muscle stimulation therapy, for example an movement therapy or an muscle activation therapy, and the medicament is administered prior to and/or during and/or after the movement therapy and a kit for the treatment of patients suffering from movement disorders comprising a medicament comprising an effective amount of a chemodenervating agent, and a device for carrying out automated movement therapy.
    Type: Application
    Filed: April 25, 2008
    Publication date: November 13, 2008
    Applicant: MERZ PHARMA GMBH & CO., KGAA
    Inventors: Florian Heinen, Susanne Grafe, Steffen Berweck, Ingo Borggraefe
  • Publication number: 20080003241
    Abstract: The present invention relates to methods for treating diseases and disorders by administering a composition containing the neurotoxic component of a Clostridium botulinum toxin complex, wherein the composition is devoid of any other protein of the Clostridium botulinum toxin complex and wherein the composition is administered at short intervals and/or in high doses.
    Type: Application
    Filed: June 29, 2007
    Publication date: January 3, 2008
    Applicant: MERZ PHARMA GMBH & CO. KGAA
    Inventors: Matthias Marx, Susanne Grafe, Reiner Benecke, Dirk Dressler