Patents by Inventor Susanne J. Szabo

Susanne J. Szabo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • T-Bet Compositions and Methods of Use Thereof
    Publication number: 20120159661
    Abstract: Isolated nucleic acid molecules encoding T-bet, and isolated T-bet polypeptides, are provided. The invention further provides antisense nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals carrying a T-bet transgene. The invention further provides T-bet fusion proteins and anti-T-bet antibodies. Methods of using the T-bet compositions of the invention are also disclosed, including methods for detecting T-bet expression and/or activity in a biological sample, methods of modulating T-bet expression and/or activity in a cell, and methods for identifying agents that modulate the expression and/or activity of T-bet.
    Type: Application
    Filed: October 31, 2011
    Publication date: June 21, 2012
    Inventors: Laurie H. Glimcher, Susanne J. Szabo
  • T-bet compositions and methods of use thereof
    Patent number: 8048672
    Abstract: Isolated nucleic acid molecules encoding T-bet, and isolated T-bet polypeptides, are provided. The invention further provides antisense nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals carrying a T-bet transgene. The invention further provides T-bet fusion proteins and anti-T-bet antibodies. Methods of using the T-bet compositions of the invention are also disclosed, including methods for detecting T-bet expression and/or activity in a biological sample, methods of modulating T-bet expression and/or activity in a cell, and methods for identifying agents that modulate the expression and/or activity of T-bet.
    Type: Grant
    Filed: December 3, 2002
    Date of Patent: November 1, 2011
    Assignee: President and Fellows of Harvard College
    Inventors: Laurie H. Glimcher, Susanne J. Szabo
  • T-bet compositions and methods of use thereof
    Patent number: 7745581
    Abstract: Isolated nucleic acid molecules encoding T-bet, and isolated T-bet proteins, are provided. The invention further provides antisense nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals carrying a T-bet transgene. The invention further provides T-bet fusion proteins and anti-T-bet antibodies. Methods of using the T-bet compositions of the invention are also disclosed, including methods for detecting T-bet activity in a biological sample, methods of modulating T-bet activity in a cell, and methods for identifying agents that modulate the activity of T-bet.
    Type: Grant
    Filed: February 21, 2008
    Date of Patent: June 29, 2010
    Assignee: President and Fellows of Harvard College
    Inventors: Laurie H. Glimcher, Susanne J. Szabo
  • T-bet compositions and methods of use thereof
    Publication number: 20080300384
    Abstract: Isolated nucleic acid molecules encoding T-bet, and isolated T-bet proteins, are provided. The invention further provides antisense nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals carrying a T-bet transgene. The invention further provides T-bet fusion proteins and anti-T-bet antibodies. Methods of using the T-bet compositions of the invention are also disclosed, including methods for detecting T-bet activity in a biological sample, methods of modulating T-bet activity in a cell, and methods for identifying agents that modulate the activity of T-bet.
    Type: Application
    Filed: February 21, 2008
    Publication date: December 4, 2008
    Applicant: President and Fellows of Harvard College
    Inventors: Laurie H. Glimcher, Susanne J. Szabo
  • T-bet compositions and methods of use thereof
    Patent number: 7393944
    Abstract: Isolated nucleic acid molecules encoding T-bet, and isolated T-bet proteins, are provided. The invention further provides antisense nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals carrying a T-bet transgene. The invention further provides T-bet fusion proteins and anti-T-bet antibodies. Methods of using the T-bet compositions of the invention are also disclosed, including methods for detecting T-bet activity in a biological sample, methods of modulating T-bet activity in a cell, and methods for identifying agents that modulate the activity of T-bet.
    Type: Grant
    Filed: December 3, 2001
    Date of Patent: July 1, 2008
    Assignee: President and Fellows of Harvard College
    Inventors: Laurie H. Glimcher, Susanne J. Szabo
  • T-bet antibodies
    Patent number: 7365169
    Abstract: Isolated nucleic acid molecules encoding T-bet, and isolated T-bet proteins, are provided. The invention further provides, e.g., anti-T-bet antibodies. Methods of using the T-bet compositions of the invention are also disclosed, including, e.g., methods for detecting T-bet activity in a biological sample.
    Type: Grant
    Filed: November 30, 2005
    Date of Patent: April 29, 2008
    Assignee: President and Fellows of Harvard College
    Inventors: Laurie H. Glimcher, Susanne J. Szabo
  • T-bet compositions and methods of use thereof
    Publication number: 20030186377
    Abstract: Isolated nucleic acid molecules encoding T-bet, and isolated T-bet polypeptides, are provided. The invention further provides antisense nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals carrying a T-bet transgene. The invention further provides T-bet fusion proteins and anti-T-bet antibodies. Methods of using the T-bet compositions of the invention are also disclosed, including methods for detecting T-bet expression and/or activity in a biological sample, methods of modulating T-bet expression and/or activity in a cell, and methods for identifying agents that modulate the expression and/or activity of T-bet.
    Type: Application
    Filed: December 3, 2002
    Publication date: October 2, 2003
    Applicant: President and Fellows of Harvard College
    Inventors: Laurie H. Glimcher, Susanne J. Szabo
  • T-bet compositions and methods of use thereof
    Publication number: 20030104528
    Abstract: Isolated nucleic acid molecules encoding T-bet, and isolated T-bet proteins, are provided. The invention further provides antisense nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals carrying a T-bet transgene. The invention further provides T-bet fusion proteins and anti-T-bet antibodies. Methods of using the T-bet compositions of the invention are also disclosed, including methods for detecting T-bet activity in a biological sample, methods of modulating T-bet activity in a cell, and methods for identifying agents that modulate the activity of T-bet.
    Type: Application
    Filed: December 3, 2001
    Publication date: June 5, 2003
    Inventors: Laurie H. Glimcher, Susanne J. Szabo