Patents by Inventor Susanne Mandala

Susanne Mandala has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Selective s1p1/edg1 receptor agonists
    Publication number: 20050070506
    Abstract: The present invention encompasses a method of treating an immunoregulatory abnormality in a mammalian patient in need of such treatment comprising administering to said patient a compound which is an agonist of the S1P1/Edg1 receptor in an amount effective for treating said immunoregulatory abnormality, wherein said compound possesses a selectivity for the S1P1/Edg1 receptor over the S1PR3/Edg3 receptor, said compound administered in an amount effective for treating said immunoregulatory abnormality. Pharmaceutical compositions are included. The invention also encompasses a method of identifying candidate compounds that are agonists of the S1P1/Edg1 receptor and which possesses a selectivity for the S1P1/Edg1 receptor over the S1PR3/Edg3 receptor.
    Type: Application
    Filed: January 14, 2003
    Publication date: March 31, 2005
    Inventors: George Doherty, Michael Forrest, Richard Hajdu, Jeffrey Hale, Li Zhen, Susanne Mandala, Sander Mills, Hugh Rosen, Edward Scolnick