Abstract: At least one example embodiment provides an improved handling of image data sets of patients.

Abstract: The invention relates to a method of determining an antimicrobial drug resistance profile for a microorganism, wherein nucleic acid sequences of the microorganism are analyzed for structural variations of the genome comprising at least a change in the genome comprising more than one base, as well as for single nucleotide polymorphisms (SNPs), as well as a method of determining an infection of a patient with a microorganism potentially resistant to antimicrobial drug treatment and a method of selecting a treatment of a patient suffering from an infection with a potentially resistant microorganism, wherein the data of the antimicrobial drug resistance profile are applied.

Abstract: Using the full repertoire of genetic information from bacterial genomes and plasmids for improved genetic resistance tests The invention relates to a method of determining an antimicrobial drug resistance profile for a microorganism, wherein nucleic acid sequences of the microorganism are analyzed for at least two genetic variations of the nucleic acid sequences comprising at least one genetic variation in a chromosome and at least one genetic variation in at least one plasmid, as well as a, e.g. diagnostic, method of determining an infection of a patient with a microorganism potentially resistant to antimicrobial drug treatment and a method of selecting a treatment of a patient suffering from an infection with a potentially resistant microorganism, wherein the data of the antimicrobial drug resistance profile are applied.

Abstract: The invention relates to a method of determining an infection of a patient with Serratia species potentially resistant to antimicrobial drug treatment, a method of selecting a treatment of a patient suffering from an antibiotic resistant Serratia infection, and a method of determining an antibiotic resistance profile for bacterial microorganisms of Serratia species, as well as computer program products used in these methods. In an exemplary method, a sample (1), is used for molecular testing (2), and then a molecular fingerprint (3) is taken. The result is then compared to a reference library (4), and the result (5) is reported.

Abstract: The invention relates to a method of determining an infection of a patient with Salmonella species potentially resistant to antimicrobial drug treatment, a method of selecting a treatment of a patient suffering from an antibiotic resistant Salmonella infection, and a method of determining an antibiotic resistance profile for bacterial microorganisms of Salmonella species, as well as computer program products used in these methods. In an exemplary method, a sample 1 is used for molecular testing 2, and then a molecular fingerprint 3 is taken. The result is then compared to a reference library 4, and the result 5 is reported.

Abstract: The invention relates to a method of determining an infection of a patient with Proteus species potentially resistant to antimicrobial drug treatment, a method of selecting a treatment of a patient suffering from an antibiotic resistant Proteus infection, and a method of determining an antibiotic resistance profile for bacterial microorganisms of Proteus species, as well as computer program products used in these methods. In an exemplary method, a sample 1, is used for molecular testing 2, and then a molecular fingerprint 3 is taken. The result is then compared to a reference library 4, and the result 5 is reported.

Abstract: The present invention relates to a method of determining an infection of a patient with at least one microorganism, particularly a bacterial microorganism, potentially resistant to antimicrobial drug treatment, a method of selecting a treatment of a patient suffering from an infection with at least one microorganism, particularly bacterial microorganism, and a method of determining an antimicrobial drug, e.g. antibiotic, resistance profile for at least one microorganism, particularly bacterial microorganism, as well as computer program products used in these methods.

Abstract: The invention relates to a method of determining an infection of a patient with Enterobacter species potentially resistant to antimicrobial drug treatment, a method of selecting a treatment of a patient suffering from an antibiotic resistant Enterobacter infection, and a method of determining an antibiotic resistance profile for bacterial microorganisms of Enterobacter species, as well as computer program products used in these methods. In an exemplary method, a sample (1), is used for molecular testing (2), and then a molecular fingerprint (3) is taken. The result is then compared to a reference library (4), and the result (5) is reported.

Abstract: Genetic resistance prediction against antimicrobial drugs in microorganism using structural changes in the genome The invention relates to a method of determining an infection of a patient with at least one microorganism, particularly a bacterial microorganism, potentially resistant to antimicrobial drug treatment, a method of selecting a treatment of a patient suffering from an infection with at least one microorganism, particularly bacterial microorganism, and a method of determining structural changes of the genome of the microorganism, particularly bacterial microorganism, comprising at least one gene, as well as computer program products used in these methods.

Abstract: The invention relates to a method of determining an infection of a patient with Pseudomonas species potentially resistant to antimicrobial drug treatment, a method of selecting a treatment of a patient suffering from an antibiotic resistant Pseudomonas infection, and a method of determining an antibiotic resistance profile for bacterial microorganisms of Pseudomonas species, as well as computer program products used in these methods. In an exemplary method, a sample 1, is used for molecular testing 2, and then a molecular fingerprint 3 is taken. The result is then compared to a reference library 4, and the result 5 is reported.

Abstract: The invention relates to a method of determining an infection of a patient with Morganella species potentially resistant to antimicrobial drug treatment, a method of selecting a treatment of a patient suffering from an antibiotic resistant Morganella infection, and a method of determining an antibiotic resistance profile for bacterial microorganisms of Morganella species, as well as computer program products used in these methods. In an exemplary method, a sample 1, is used for molecular testing 2, and then a molecular fingerprint 3 is taken. The result is then compared to a reference library 4, and the result 5 is reported.

Abstract: The invention relates to a method of determining an infection of a patient with Stenotrophomonas species potentially resistant to antimicrobial drug treatment, a method of selecting a treatment of a patient suffering from an antibiotic resistant Stenotrophomonas infection, and a method of determining an antibiotic resistance profile for bacterial microorganisms of Stenotrophomonas species, as well as computer program products used in these methods. In an exemplary method, a sample 1, is used for molecular testing 2, and then a molecular fingerprint 3 is taken. The result is then compared to a reference library 4, and the result 5 is reported.

Abstract: The invention relates to a method of determining an infection of a patient with Acinetobacter species potentially resistant to antimicrobial drug treatment, a method of selecting a treatment of a patient suffering from an antibiotic resistant Acinetobacter infection, and a method of determining an anti-biotic resistance profile for bacterial microorganisms of Acinetobacter species, as well as computer program products used in these methods. In an exemplary method, a sample 1, is used for molecular testing 2, and then a molecular finger-print 3 is taken. The result is then compared to a reference library 4, and the result 5 is reported.

Abstract: The invention relates to a method of determining an infection of a patient with Shigella species potentially resistant to antimicrobial drug treatment, a method of selecting a treatment of a patient suffering from an antibiotic resistant Shigella infection, and a method of determining an antibiotic resistance profile for bacterial microorganisms of Shigella species, as well as computer program products used in these methods. In an exemplary method, a sample 1, is used for molecular testing 2, and then a molecular fingerprint 3 is taken. The result is then compared to a reference library 4, and the result 5 is reported.

Abstract: The invention relates to a method of determining an infection of a patient with Klebsiella species potentially resistant to antimicrobial drug treatment by detecting mutations in the genes, parC, KPN 01607, gyrA, KPN 02451, baeR, aceF, ybgH, ynjE, KPN 01951, KPN 01961, KPN 02114, mhpA, KPN 02128, KPN 02144, KPN 02149, ydiJ, btuE, oppC, pth, KPN 02298, KPN 02302, dadA, yoaA, ftn, cbl, hisB, yegQ, yehY, KPN 02580, yejH, KPN 02621, yfaW, KPN 02170, KPN 02025, livG, livM, livH, fliY, yedQ, abgB, treA, baeS, KPN 02399, ydcR, anmK, ccmF, KPN 02440, KPN 02540, KPN 01752, and KPN 04195, and/or KOX 26125, KOX 13365, KOX 16735, KOX 25695, KOX 12270, and KOX 15055; a method of selecting a treatment of a patient suffering from an antibiotic resistant Klebsiella infection; and a method of determining an antibiotic resistance profile for bacterial microorganisms of Klebsiella species, as well as computer program products used in these methods.

Abstract: The embodiments relate to a method of determining an antibiotic resistance profile for a bacterial microorganism and to a method of determining the resistance of a bacterial microorganism to an antibiotic drug, wherein the bacterial microorganism belongs to the species Escherichia coli (E. coli). The method includes determining a nucleic acid sequence information or determining the presence of a mutation of at least one gene.

Abstract: In a method and apparatus to automatically display and/or measure bone variations in medical image data, an image data set of an examination region is acquired and the bone regions in the image data set are automatically segmented in a first segmentation followed by a second segmentation in which bone variation regions in the image data set are automatically segmented on the basis of the results of the first segmentation. The results of the first and/or second segmentations are stored and/or displayed.

Abstract: A method is disclosed for determining analysis information supporting a user assessing the effect of a biological agent on the treatment of a rheumatic disease. The method includes, subsequent to starting the administration of the biological agent: recording a first morphological magnetic resonance imaging record of at least one target joint using a first magnetic resonance sequence; recording a second magnetic resonance imaging record showing the blood flow through the target joint by perfusion imaging using a second magnetic resonance sequence; determining at least a first measuring parameter related to the morphology of the joint by analysis of the first magnetic resonance imaging record and at least a second measuring parameter describing the blood flow in the target joint by analysis of the second magnetic resonance imaging record; and automatic determination of the analysis information from the first and the second measuring parameter.

Abstract: In a method and apparatus to automatically display and/or measure bone variations in medical image data, an image data set of an examination region is acquired and the bone regions in the image data set are automatically segmented in a first segmentation followed by a second segmentation in which bone variation regions in the image data set are automatically segmented on the basis of the results of the first segmentation. The results of the first and/or second segmentations are stored and/or displayed.

Abstract: At least one embodiment of the invention relates to bone marrow precursor cells or bone marrow cells of a patient, the cells labeled with at least one contrast agent suitable for an imaging method, for use in an imaging method for diagnosing a metastasizing cancer, wherein the local accumulation of the labeled precursor cells or bone marrow cells indicates the presence of a metastasizing tumor growth. At least one embodiment also relates to a method for imaging a metastasizing tumor tissue in a patient, wherein a) bone marrow precursor cells or bone marrow cells are extracted from a patient, b) these precursor cells or bone marrow cells are labeled with at least one contrast agent suitable for an imaging method, c) the precursor cells or bone marrow cells thus labeled are retransplanted or reinjected into the patient, and d) the presence of metastasizing tumor cells is depicted with an imaging method.