Patents by Inventor Susanne Szabo

Susanne Szabo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modulation of Th2 lineage commitment by T-bet
    Publication number: 20060223116
    Abstract: The instant invention is based, at least in part, on the identification of a mechanism by which T-bet directly modulates Th2 cytokine production. The present invention pertains to methods of identifying agents that modulate the Tec kinase-mediated interaction of T-bet with GATA-3, as well as methods of use therefore.
    Type: Application
    Filed: January 20, 2006
    Publication date: October 5, 2006
    Inventors: Laurie Glimcher, Susanne Szabo, Eun Hwang
  • T-bet compositions and methods of use thereof
    Publication number: 20060084118
    Abstract: Isolated nucleic acid molecules encoding T-bet, and isolated T-bet proteins, are provided. The invention further provides antisense nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals carrying a T-bet transgene. The invention further provides T-bet fusion proteins and anti-T-bet antibodies. Methods of using the T-bet compositions of the invention are also disclosed, including methods for detecting T-bet activity in a biological sample, methods of modulating T-bet activity in a cell, and methods for identifying agents that modulate the activity of T-bet.
    Type: Application
    Filed: November 30, 2005
    Publication date: April 20, 2006
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Laurie Glimcher, Susanne Szabo