Patents by Inventor Susanta K. Sarkar

Susanta K. Sarkar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF PURIFYING ACTIVE SOLUBLE MATRIX METALLOPROTEINASES
    Publication number: 20210348148
    Abstract: A method for purifying activated human MMP in E. coli without the use of urea or APMA is provided. In the method, a non-ionic detergent is used in a lysis buffer to solubilize MMP, and the protease activities of trypsin and MMP are utilized to digest the E. coli proteins and activate pro-MMP1.
    Type: Application
    Filed: July 19, 2021
    Publication date: November 11, 2021
    Inventors: Lokender KUMAR, Susanta K. SARKAR
  • METHOD OF PREVENTING OR REDUCING BIOFILM FORMATION
    Publication number: 20190282677
    Abstract: A method of disrupting or reducing a biofilm, the methods comprising contacting the biofilm with a matrix metalloproteinase (MMP). The biofilm may be present on inanimate or biological surfaces. Also, the MMP may be used to prevent the growth of a biofilm on an item, such as a medical device, by applying the MMP to the item. Also, therapeutic compositions comprising the MMP, which may be used to treat an individual having a biofilm-associated disease or disorder.
    Type: Application
    Filed: March 15, 2019
    Publication date: September 19, 2019
    Inventors: Lokender KUMAR, Susanta K. SARKAR
  • PURIFICATION OF ACTIVE SOLUBLE RECOMBINANT MATRIX METALLOPROTEINASE IN ESCHERICHIA COLI
    Publication number: 20190233808
    Abstract: A method for purifying activated human MMP in E. coli without the use of urea or APMA is provided. In the method, a non-ionic detergent is used in a lysis buffer to solubilize MMP, and the protease activities of trypsin and MMP are utilized to digest the E. coli proteins and activate pro-MMP 1.
    Type: Application
    Filed: February 1, 2019
    Publication date: August 1, 2019
    Inventors: Lokender Kumar, Susanta K. Sarkar
  • Immuno imaging agent for use with antibody-drug conjugate therapy
    Patent number: 9989524
    Abstract: The invention relates to a companion diagnostic antibody-like binding protein based on the humanized monoclonal antibody, DS6, to be used as diagnostic tool for in vivo detection and quantification of the tumor-associated MUC1-sialoglycotope, CA6.
    Type: Grant
    Filed: February 5, 2014
    Date of Patent: June 5, 2018
    Assignee: SANOFI
    Inventors: Jochen Kruip, Susanta K. Sarkar, Mathias Gebauer, Christian Lange, Ingo Focken
  • Immuno imaging agent for use with antibody-drug conjugate therapy
    Patent number: 9844607
    Abstract: The invention relates to a companion diagnostic antibody-like binding protein based on the humanized monoclonal antibody, DS6, to be used as diagnostic tool for in vivo detection and quantification of the tumor-associated MUC1-sialoglycotope, CA6.
    Type: Grant
    Filed: February 5, 2014
    Date of Patent: December 19, 2017
    Assignees: SANOFI, THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: Jochen Kruip, Sanjiv S. Gambhir, Susanta K. Sarkar, Mathias Gebauer, Christian Lange, Ingo Focken, Richard Kimura, Arutselvan Natarajan, Ohad Ilovich
  • IMMUNO IMAGING AGENT FOR USE WITH ANTIBODY-DRUG CONJUGATE THERAPY
    Publication number: 20140255305
    Abstract: The invention relates to a companion diagnostic antibody-like binding protein based on the humanized monoclonal antibody, DS6, to be used as diagnostic tool for in vivo detection and quantification of the tumor-associated MUC1-sialoglycotope, CA6.
    Type: Application
    Filed: February 5, 2014
    Publication date: September 11, 2014
    Inventors: Jochen Kruip, Sanjiv S. Gambhir, Susanta K. Sarkar, Mathias Gebauer, Christian Lange, Ingo Focken, Richard Kimura, Arutselvan Natarajan, Ohad Ilovich
  • IMMUNO IMAGING AGENT FOR USE WITH ANTIBODY-DRUG CONJUGATE THERAPY
    Publication number: 20140256916
    Abstract: The invention relates to a companion diagnostic antibody-like binding protein based on the humanized monoclonal antibody, DS6, to be used as diagnostic tool for in vivo detection and quantification of the tumor-associated MUC1-sialoglycotope, CA6.
    Type: Application
    Filed: February 5, 2014
    Publication date: September 11, 2014
    Inventors: Jochen Kruip, Susanta K. Sarkar, Mathias Gebauer, Christian Lange, Ingo Focken