Patents by Inventor Sushant Omprakash Dube
Sushant Omprakash Dube has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250082617Abstract: Liquid pharmaceutical compositions of apixaban or pharmaceutically acceptable salts thereof are described. More specifically, stable oral liquid pharmaceutical compositions of apixaban for oral administration are provided, wherein the composition is stable for extended periods of time. More specifically, stable liquid pharmaceutical compositions of apixaban at concentrations of 0.4 mg/mL or more are provided. Stable oral liquid compositions of apixaban, methods for their administration, processes for their production, and use of these compositions for treatment of diseases treatable by apixaban are disclosed.Type: ApplicationFiled: November 27, 2024Publication date: March 13, 2025Applicant: Slayback Pharma LLCInventors: Sushant Omprakash Dube, Girish G. Kore, Naga Venkata Durga Prasad Ketha, Sumitra Ashokkumar Pillai, Praveen Kumar Subbappa
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Patent number: 12213972Abstract: The present invention relates to stable pharmaceutical compositions comprising apixaban or its pharmaceutically acceptable salts thereof. The present invention further relates to a capsule composition comprising a therapeutically effective amount of apixaban solubilized or dispersed in a pharmaceutically acceptable carrier, wherein the therapeutically effective amount of apixaban ranges from about 0.5 mg/unit dosage form to about 50 mg/unit dosage form. The present invention also provides manufacturing processes thereof and use of the said compositions for prevention, treatment or prophylaxis of disorders in human patients in need thereof.Type: GrantFiled: January 23, 2024Date of Patent: February 4, 2025Assignee: SLAYBACK PHARMA LLCInventors: Shailendra Mandge, Venkateshwar Reddy Keesara, Harish Gunda, Naga Venkata Durga Prasad Ketha, Satheesh Balasubramanian, Sumitra Ashokkumar Pillai, Sushant Omprakash Dube, Praveen Kumar Subbappa
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Publication number: 20250025456Abstract: Pharmaceutical compositions are provided, which comprise cabozantinib or pharmaceutically acceptable salts thereof, and at least one pharmaceutically acceptable excipient, wherein the inventive compositions exhibit enhanced bioavailability compared to the currently marketed or commercially available formulations. The present invention also provides manufacturing processes thereof and use of the said inventive compositions for the prevention, treatment or prophylaxis of disorders in human patients in need thereof. The present invention relates to oral pharmaceutical compositions of cabozantinib, methods for their administration, processes for their production, and use of these compositions for treatment of diseases treatable by cabozantinib.Type: ApplicationFiled: September 30, 2024Publication date: January 23, 2025Applicant: SLAYBACK PHARMA LLCInventors: Sushant Omprakash DUBE, Suprit Dilip SAOJI, Pankaj Kisan CHATKI, Sumitra Ashokkumar PILLAI, Girish G. KORE
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Patent number: 12194028Abstract: Liquid pharmaceutical compositions of apixaban or pharmaceutically acceptable salts thereof are described. More specifically, stable oral liquid pharmaceutical compositions of apixaban for oral administration are provided, wherein the composition is stable for extended periods of time. More specifically, stable liquid pharmaceutical compositions of apixaban at concentrations of 0.4 mg/mL or more are provided. Stable oral liquid compositions of apixaban, methods for their administration, processes for their production, and use of these compositions for treatment of diseases treatable by apixaban are disclosed.Type: GrantFiled: March 6, 2023Date of Patent: January 14, 2025Assignee: SLAYBACK PHARMA LLCInventors: Sushant Omprakash Dube, Girish G. Kore, Naga Venkata Durga Prasad Ketha, Sumitra Ashokkumar Pillai, Praveen Kumar Subbappa
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Patent number: 12138255Abstract: Pharmaceutical compositions are provided, which comprise cabozantinib or pharmaceutically acceptable salts thereof, and at least one pharmaceutically acceptable excipient, wherein the inventive compositions exhibit enhanced bioavailability compared to the currently marketed or commercially available formulations. The present invention also provides manufacturing processes thereof and use of the said inventive compositions for the prevention, treatment or prophylaxis of disorders in human patients in need thereof. The present invention relates to oral pharmaceutical compositions of cabozantinib, methods for their administration, processes for their production, and use of these compositions for treatment of diseases treatable by cabozantinib.Type: GrantFiled: May 5, 2023Date of Patent: November 12, 2024Assignee: SLAYBACK PHARMA LLCInventors: Sushant Omprakash Dube, Suprit Dilip Saoji, Pankaj Kisan Chatki, Sumitra Ashokkumar Pillai, Girish G. Kore
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Publication number: 20240285582Abstract: The present invention relates to liquid pharmaceutical compositions of edaravone. More specifically, stable solutions of edaravone for enteral administration are provided, wherein the composition is stable for extended period of time. The present invention further relates to stable solutions of edaravone, methods for their administration, processes for their production, and use of these compositions for treatment of diseases treatable by edaravone.Type: ApplicationFiled: June 23, 2023Publication date: August 29, 2024Applicant: Slayback Pharma LLCInventors: Sushant Omprakash Dube, Girish G. Kore, Abhijit Balaji Pawar, Jagdish Lotan Lohar, Praveen Kumar Subbappa, Sumitra Ashokkumar Pillai, Parvateesam Yenda, Satheesh Balasubramanian
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Publication number: 20240207278Abstract: Liquid pharmaceutical compositions of tofacitinib or its pharmaceutically acceptable salts thereof are described, which are suitable for oral administration, and which are stable under varying storage conditions for extended periods of time. Methods of treating auto-immune disorders are also described, using the stable liquid pharmaceutical compositions of tofacitinib. A stable liquid pharmaceutical composition of tofacitinib according to the invention comprises of (a) tofacitinib at a concentration of about 1 mg/mL or more; (b) a pharmaceutically acceptable liquid vehicle; (c) at least one anti-oxidant; and (d) optionally one or more other pharmaceutically acceptable excipients.Type: ApplicationFiled: March 7, 2024Publication date: June 27, 2024Applicant: SLAYBACK PHARMA LLCInventors: Sushant Omprakash DUBE, Purushottam Dattatraya KULKARNI, Purushottam Sakhahari PATTEWAR, Sumitra Ashokkumar PILLAI
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Publication number: 20240197705Abstract: The present invention relates to stable pharmaceutical compositions comprising apixaban or its pharmaceutically acceptable salts thereof. The present invention further relates to a capsule composition comprising a therapeutically effective amount of apixaban solubilized or dispersed in a pharmaceutically acceptable carrier, wherein the therapeutically effective amount of apixaban ranges from about 0.5 mg/unit dosage form to about 50 mg/unit dosage form. The present invention also provides manufacturing processes thereof and use of the said compositions for prevention, treatment or prophylaxis of disorders in human patients in need thereof.Type: ApplicationFiled: January 23, 2024Publication date: June 20, 2024Applicant: Slayback Pharma LLCInventors: Shailendra Mandge, Venkateshwar Reddy Keesara, Harish Gunda, Naga Venkata Durga Prasad Ketha, Satheesh Balasubramanian, Sumitra Ashokkumar Pillai, Sushant Omprakash Dube, Praveen Kumar Subbappa
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Publication number: 20240189229Abstract: Liquid pharmaceutical compositions of baclofen or a pharmaceutically acceptable salt thereof are described. More specifically, stable liquid pharmaceutical compositions of baclofen at concentrations of 2 mg/mL or more are provided. Preferably, the liquid pharmaceutical compositions are suitable for oral administration, and stable at pH ranges of 3-8 over a variety of storage conditions, including long-term storage for extended periods of time. Various methods for preparing stable liquid pharmaceutical compositions of baclofen are described. Methods of treating spasticity using the inventive pharmaceutical compositions are also provided.Type: ApplicationFiled: February 27, 2023Publication date: June 13, 2024Applicant: ANI Pharmaceuticals, Inc.Inventors: Sushant Omprakash Dube, Suprit Dilip Saoji, Girish G. Kore, Abhijit Balaji Pawar, Purushottam Sakhahari Pattewar, Pankaj Kisan Chatki, Sumitra Ashokkumar Pillai, Praveen Kumar Subbappa
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Publication number: 20240173282Abstract: The present invention relates to stable liquid pharmaceutical compositions of baclofen or a pharmaceutically acceptable salt thereof including baclofen at concentrations of equal to or more than 2 mg/ml or more. Preferably, the liquid pharmaceutical compositions of baclofen are suitable for oral administration and are stable at wider pH ranges over a variety of storage conditions, including long-term storage for extended periods of time. Methods of treating various disorders using the inventive pharmaceutical compositions are also provided.Type: ApplicationFiled: February 9, 2024Publication date: May 30, 2024Applicant: ANI Pharmaceuticals, Inc.Inventors: Sushant Omprakash Dube, Purushottam Sakhahari Pattewar, Pankaj Kisan Chatki, Sumitra Ashokkumar Pillai
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Publication number: 20240131018Abstract: Pharmaceutical compositions suitable for oral administration (such as a tablet or a capsule) are provided, which comprise a therapeutically effective amount of an amorphous solid dispersion of cabozantinib, e.g., for treating a proliferative disorder. Preferably, the amorphous solid dispersion consists of (a) cabozantinib or a pharmaceutically acceptable salt thereof (such as cabozantinib (S)-malate); (b) at least one pharmaceutically acceptable carrier selected from the group consisting of hydroxypropyl methyl cellulose acetate succinate (HPMC-AS), polyvinyl pyrrolidine and vinyl acetate (PVP/VA) copolymer, hydroxypropyl methylcellulose phthalate (HPMCP), and mixtures thereof; (c) a pore-forming agent; and (d) a plasticizer.Type: ApplicationFiled: November 29, 2023Publication date: April 25, 2024Applicant: SLAYBACK PHARMA LLCInventors: Sushant Omprakash DUBE, Suprit Dilip SAOJI, Pankaj Kisan CHATKI, Sumitra Ashokkumar PILLAI, Girish G. KORE
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Patent number: 11957685Abstract: Liquid pharmaceutical compositions of tofacitinib or its pharmaceutically acceptable salts thereof are described, which are suitable for oral administration, and which are stable under varying storage conditions for extended periods of time. Methods of treating auto-immune disorders are also described, using the stable liquid pharmaceutical compositions of tofacitinib. A stable liquid pharmaceutical composition of tofacitinib according to the invention comprises of (a) tofacitinib at a concentration of about 1 mg/mL or more; (b) a pharmaceutically acceptable liquid vehicle; (c) at least one anti-oxidant; and (d) optionally one or more other pharmaceutically acceptable excipients.Type: GrantFiled: August 10, 2023Date of Patent: April 16, 2024Assignee: SLAYBACK PHARMA LLCInventors: Sushant Omprakash Dube, Purushottam Dattatraya Kulkarni, Purushottam Sakhahari Pattewar, Sumitra Ashokkumar Pillai
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Publication number: 20240050416Abstract: The present invention relates to stable pharmaceutical compositions comprising apixaban or its pharmaceutically acceptable salts thereof. The present invention further relates to a capsule composition comprising a therapeutically effective amount of apixaban solubilized or dispersed in a pharmaceutically acceptable carrier, wherein the therapeutically effective amount of apixaban ranges from about 0.5 mg/unit dosage form to about 50 mg/unit dosage form. The present invention also provides manufacturing processes thereof and use of the said compositions for prevention, treatment or prophylaxis of disorders in human patients in need thereof.Type: ApplicationFiled: July 24, 2023Publication date: February 15, 2024Applicant: Slayback Pharma LLCInventors: Shailendra Mandge, Venkateshwar Reddy Keesara, Harish Gunda, Naga Venkata Durga Prasad Ketha, Satheesh Balasubramanian, Sumitra Ashokkumar Pillai, Sushant Omprakash Dube, Praveen Kumar Subbappa
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Publication number: 20240016771Abstract: The present invention relates to stable liquid pharmaceutical compositions of baclofen or a pharmaceutically acceptable salt thereof. More specifically, stable oral suspensions of baclofen at concentrations of equal to or more than 2 mg/mL or more are provided. Preferably, the liquid pharmaceutical compositions of baclofen are suitable for oral administration and are stable at wider pH ranges over a variety of storage conditions, including long-term storage for extended periods of time. Methods of treating various disorders using the inventive pharmaceutical compositions are also provided. The invention further relates to various methods for preparing stable suspension of baclofen.Type: ApplicationFiled: September 26, 2023Publication date: January 18, 2024Applicant: ANI Pharmaceuticals, Inc.Inventors: Sushant Omprakash Dube, Purushottam Sakhahari Pattewar, Pankaj Kisan Chatki, Sumitra Ashokkumar Pillai
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Patent number: 11857524Abstract: The present invention relates to stable liquid pharmaceutical compositions of baclofen or a pharmaceutically acceptable salt thereof. More specifically, stable oral suspensions of baclofen at concentrations of equal to or more than 2 mg/mL or more are provided. Preferably, the liquid pharmaceutical compositions of baclofen are suitable for oral administration and are stable at wider pH ranges over a variety of storage conditions, including long-term storage for extended periods of time. Methods of treating various disorders using the inventive pharmaceutical compositions are also provided. The invention further relates to various methods for preparing stable suspension of baclofen.Type: GrantFiled: April 4, 2023Date of Patent: January 2, 2024Assignee: ANI Pharmaceuticals, Inc.Inventors: Sushant Omprakash Dube, Purushottam Sakhahari Pattewar, Pankaj Kisan Chatki, Sumitra Ashokkumar Pillai
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Publication number: 20230398120Abstract: Liquid pharmaceutical compositions of tofacitinib or its pharmaceutically acceptable salts thereof are described, which are suitable for oral administration, and which are stable under varying storage conditions for extended periods of time. Methods of treating auto-immune disorders are also described, using the stable liquid pharmaceutical compositions of tofacitinib. A stable liquid pharmaceutical composition of tofacitinib according to the invention comprises of (a) tofacitinib at a concentration of about 1 mg/mL or more; (b) a pharmaceutically acceptable liquid vehicle; (c) at least one anti-oxidant; and (d) optionally one or more other pharmaceutically acceptable excipients.Type: ApplicationFiled: August 10, 2023Publication date: December 14, 2023Applicant: SLAYBACK PHARMA LLCInventors: Sushant Omprakash DUBE, Purushottam Dattatraya KULKARNI, Purushottam Sakhahari PATTEWAR, Sumitra Ashokkumar PILLAI
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Patent number: 11766438Abstract: The present invention relates to liquid pharmaceutical compositions of tofacitinib or its pharmaceutically acceptable salts thereof, suitable for oral administration, that are stable under varying storage conditions for extended periods of time. The present invention also relates to methods of treating auto-immune disorders using the stable liquid pharmaceutical compositions of tofacitinib. A stable liquid pharmaceutical composition of tofacitinib according to the invention comprises of (a) tofacitinib at a concentration of about 1 mg/mL or more; (b) a pharmaceutically acceptable liquid vehicle; (c) at least one anti-oxidant; and (d) optionally one or more other pharmaceutically acceptable excipients.Type: GrantFiled: April 23, 2021Date of Patent: September 26, 2023Assignee: SLAYBACK PHARMA LLCInventors: Sushant Omprakash Dube, Purushottam Dattatraya Kulkarni, Purushottam Sakhahari Pattewar, Sumitra Ashokkumar Pillai
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Publication number: 20230285341Abstract: The present invention relates to stable liquid pharmaceutical compositions of baclofen or a pharmaceutically acceptable salt thereof. More specifically, stable oral suspensions of baclofen at concentrations of equal to or more than 2 mg/mL or more are provided. Preferably, the liquid pharmaceutical compositions of baclofen are suitable for oral administration and are stable at wider pH ranges over a variety of storage conditions, including long-term storage for extended periods of time. Methods of treating various disorders using the inventive pharmaceutical compositions are also provided. The invention further relates to various methods for preparing stable suspension of baclofen.Type: ApplicationFiled: April 4, 2023Publication date: September 14, 2023Applicant: SLAYBACK PHARMA LLCInventors: Sushant Omprakash Dube, Purushottam Sakhahari Pattewar, Pankaj Kisan Chatki, Sumitra Ashokkumar Pillai
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Publication number: 20230285368Abstract: Liquid pharmaceutical compositions of apixaban or pharmaceutically acceptable salts thereof are described. More specifically, stable oral liquid pharmaceutical compositions of apixaban for oral administration are provided, wherein the composition is stable for extended periods of time. More specifically, stable liquid pharmaceutical compositions of apixaban at concentrations of 0.4 mg/mL or more are provided. Stable oral liquid compositions of apixaban, methods for their administration, processes for their production, and use of these compositions for treatment of diseases treatable by apixaban are disclosed.Type: ApplicationFiled: March 6, 2023Publication date: September 14, 2023Applicant: Slayback Pharma LLCInventors: Sushant Omprakash Dube, Girish G. Kore, Naga Venkata Durga Prasad Ketha, Sumitra Ashokkumar Pillai, Praveen Kumar Subbappa
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Publication number: 20230270736Abstract: Pharmaceutical compositions are provided, which comprise cabozantinib or pharmaceutically acceptable salts thereof, and at least one pharmaceutically acceptable excipient, wherein the inventive compositions exhibit enhanced bioavailability compared to the currently marketed or commercially available formulations. The present invention also provides manufacturing processes thereof and use of the said inventive compositions for the prevention, treatment or prophylaxis of disorders in human patients in need thereof. The present invention relates to oral pharmaceutical compositions of cabozantinib, methods for their administration, processes for their production, and use of these compositions for treatment of diseases treatable by cabozantinib.Type: ApplicationFiled: May 5, 2023Publication date: August 31, 2023Applicant: SLAYBACK PHARMA LLCInventors: Sushant Omprakash DUBE, Suprit Dilip SAOJI, Pankaj Kisan CHATKI, Sumitra Ashokkumar PILLAI, Girish G. KORE