Patents by Inventor Sushant Omprakash Dube

Sushant Omprakash Dube has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250082617
    Abstract: Liquid pharmaceutical compositions of apixaban or pharmaceutically acceptable salts thereof are described. More specifically, stable oral liquid pharmaceutical compositions of apixaban for oral administration are provided, wherein the composition is stable for extended periods of time. More specifically, stable liquid pharmaceutical compositions of apixaban at concentrations of 0.4 mg/mL or more are provided. Stable oral liquid compositions of apixaban, methods for their administration, processes for their production, and use of these compositions for treatment of diseases treatable by apixaban are disclosed.
    Type: Application
    Filed: November 27, 2024
    Publication date: March 13, 2025
    Applicant: Slayback Pharma LLC
    Inventors: Sushant Omprakash Dube, Girish G. Kore, Naga Venkata Durga Prasad Ketha, Sumitra Ashokkumar Pillai, Praveen Kumar Subbappa
  • Patent number: 12213972
    Abstract: The present invention relates to stable pharmaceutical compositions comprising apixaban or its pharmaceutically acceptable salts thereof. The present invention further relates to a capsule composition comprising a therapeutically effective amount of apixaban solubilized or dispersed in a pharmaceutically acceptable carrier, wherein the therapeutically effective amount of apixaban ranges from about 0.5 mg/unit dosage form to about 50 mg/unit dosage form. The present invention also provides manufacturing processes thereof and use of the said compositions for prevention, treatment or prophylaxis of disorders in human patients in need thereof.
    Type: Grant
    Filed: January 23, 2024
    Date of Patent: February 4, 2025
    Assignee: SLAYBACK PHARMA LLC
    Inventors: Shailendra Mandge, Venkateshwar Reddy Keesara, Harish Gunda, Naga Venkata Durga Prasad Ketha, Satheesh Balasubramanian, Sumitra Ashokkumar Pillai, Sushant Omprakash Dube, Praveen Kumar Subbappa
  • Publication number: 20250025456
    Abstract: Pharmaceutical compositions are provided, which comprise cabozantinib or pharmaceutically acceptable salts thereof, and at least one pharmaceutically acceptable excipient, wherein the inventive compositions exhibit enhanced bioavailability compared to the currently marketed or commercially available formulations. The present invention also provides manufacturing processes thereof and use of the said inventive compositions for the prevention, treatment or prophylaxis of disorders in human patients in need thereof. The present invention relates to oral pharmaceutical compositions of cabozantinib, methods for their administration, processes for their production, and use of these compositions for treatment of diseases treatable by cabozantinib.
    Type: Application
    Filed: September 30, 2024
    Publication date: January 23, 2025
    Applicant: SLAYBACK PHARMA LLC
    Inventors: Sushant Omprakash DUBE, Suprit Dilip SAOJI, Pankaj Kisan CHATKI, Sumitra Ashokkumar PILLAI, Girish G. KORE
  • Patent number: 12194028
    Abstract: Liquid pharmaceutical compositions of apixaban or pharmaceutically acceptable salts thereof are described. More specifically, stable oral liquid pharmaceutical compositions of apixaban for oral administration are provided, wherein the composition is stable for extended periods of time. More specifically, stable liquid pharmaceutical compositions of apixaban at concentrations of 0.4 mg/mL or more are provided. Stable oral liquid compositions of apixaban, methods for their administration, processes for their production, and use of these compositions for treatment of diseases treatable by apixaban are disclosed.
    Type: Grant
    Filed: March 6, 2023
    Date of Patent: January 14, 2025
    Assignee: SLAYBACK PHARMA LLC
    Inventors: Sushant Omprakash Dube, Girish G. Kore, Naga Venkata Durga Prasad Ketha, Sumitra Ashokkumar Pillai, Praveen Kumar Subbappa
  • Patent number: 12138255
    Abstract: Pharmaceutical compositions are provided, which comprise cabozantinib or pharmaceutically acceptable salts thereof, and at least one pharmaceutically acceptable excipient, wherein the inventive compositions exhibit enhanced bioavailability compared to the currently marketed or commercially available formulations. The present invention also provides manufacturing processes thereof and use of the said inventive compositions for the prevention, treatment or prophylaxis of disorders in human patients in need thereof. The present invention relates to oral pharmaceutical compositions of cabozantinib, methods for their administration, processes for their production, and use of these compositions for treatment of diseases treatable by cabozantinib.
    Type: Grant
    Filed: May 5, 2023
    Date of Patent: November 12, 2024
    Assignee: SLAYBACK PHARMA LLC
    Inventors: Sushant Omprakash Dube, Suprit Dilip Saoji, Pankaj Kisan Chatki, Sumitra Ashokkumar Pillai, Girish G. Kore
  • Publication number: 20240285582
    Abstract: The present invention relates to liquid pharmaceutical compositions of edaravone. More specifically, stable solutions of edaravone for enteral administration are provided, wherein the composition is stable for extended period of time. The present invention further relates to stable solutions of edaravone, methods for their administration, processes for their production, and use of these compositions for treatment of diseases treatable by edaravone.
    Type: Application
    Filed: June 23, 2023
    Publication date: August 29, 2024
    Applicant: Slayback Pharma LLC
    Inventors: Sushant Omprakash Dube, Girish G. Kore, Abhijit Balaji Pawar, Jagdish Lotan Lohar, Praveen Kumar Subbappa, Sumitra Ashokkumar Pillai, Parvateesam Yenda, Satheesh Balasubramanian
  • Publication number: 20240207278
    Abstract: Liquid pharmaceutical compositions of tofacitinib or its pharmaceutically acceptable salts thereof are described, which are suitable for oral administration, and which are stable under varying storage conditions for extended periods of time. Methods of treating auto-immune disorders are also described, using the stable liquid pharmaceutical compositions of tofacitinib. A stable liquid pharmaceutical composition of tofacitinib according to the invention comprises of (a) tofacitinib at a concentration of about 1 mg/mL or more; (b) a pharmaceutically acceptable liquid vehicle; (c) at least one anti-oxidant; and (d) optionally one or more other pharmaceutically acceptable excipients.
    Type: Application
    Filed: March 7, 2024
    Publication date: June 27, 2024
    Applicant: SLAYBACK PHARMA LLC
    Inventors: Sushant Omprakash DUBE, Purushottam Dattatraya KULKARNI, Purushottam Sakhahari PATTEWAR, Sumitra Ashokkumar PILLAI
  • Publication number: 20240197705
    Abstract: The present invention relates to stable pharmaceutical compositions comprising apixaban or its pharmaceutically acceptable salts thereof. The present invention further relates to a capsule composition comprising a therapeutically effective amount of apixaban solubilized or dispersed in a pharmaceutically acceptable carrier, wherein the therapeutically effective amount of apixaban ranges from about 0.5 mg/unit dosage form to about 50 mg/unit dosage form. The present invention also provides manufacturing processes thereof and use of the said compositions for prevention, treatment or prophylaxis of disorders in human patients in need thereof.
    Type: Application
    Filed: January 23, 2024
    Publication date: June 20, 2024
    Applicant: Slayback Pharma LLC
    Inventors: Shailendra Mandge, Venkateshwar Reddy Keesara, Harish Gunda, Naga Venkata Durga Prasad Ketha, Satheesh Balasubramanian, Sumitra Ashokkumar Pillai, Sushant Omprakash Dube, Praveen Kumar Subbappa
  • Publication number: 20240189229
    Abstract: Liquid pharmaceutical compositions of baclofen or a pharmaceutically acceptable salt thereof are described. More specifically, stable liquid pharmaceutical compositions of baclofen at concentrations of 2 mg/mL or more are provided. Preferably, the liquid pharmaceutical compositions are suitable for oral administration, and stable at pH ranges of 3-8 over a variety of storage conditions, including long-term storage for extended periods of time. Various methods for preparing stable liquid pharmaceutical compositions of baclofen are described. Methods of treating spasticity using the inventive pharmaceutical compositions are also provided.
    Type: Application
    Filed: February 27, 2023
    Publication date: June 13, 2024
    Applicant: ANI Pharmaceuticals, Inc.
    Inventors: Sushant Omprakash Dube, Suprit Dilip Saoji, Girish G. Kore, Abhijit Balaji Pawar, Purushottam Sakhahari Pattewar, Pankaj Kisan Chatki, Sumitra Ashokkumar Pillai, Praveen Kumar Subbappa
  • Publication number: 20240173282
    Abstract: The present invention relates to stable liquid pharmaceutical compositions of baclofen or a pharmaceutically acceptable salt thereof including baclofen at concentrations of equal to or more than 2 mg/ml or more. Preferably, the liquid pharmaceutical compositions of baclofen are suitable for oral administration and are stable at wider pH ranges over a variety of storage conditions, including long-term storage for extended periods of time. Methods of treating various disorders using the inventive pharmaceutical compositions are also provided.
    Type: Application
    Filed: February 9, 2024
    Publication date: May 30, 2024
    Applicant: ANI Pharmaceuticals, Inc.
    Inventors: Sushant Omprakash Dube, Purushottam Sakhahari Pattewar, Pankaj Kisan Chatki, Sumitra Ashokkumar Pillai
  • Publication number: 20240131018
    Abstract: Pharmaceutical compositions suitable for oral administration (such as a tablet or a capsule) are provided, which comprise a therapeutically effective amount of an amorphous solid dispersion of cabozantinib, e.g., for treating a proliferative disorder. Preferably, the amorphous solid dispersion consists of (a) cabozantinib or a pharmaceutically acceptable salt thereof (such as cabozantinib (S)-malate); (b) at least one pharmaceutically acceptable carrier selected from the group consisting of hydroxypropyl methyl cellulose acetate succinate (HPMC-AS), polyvinyl pyrrolidine and vinyl acetate (PVP/VA) copolymer, hydroxypropyl methylcellulose phthalate (HPMCP), and mixtures thereof; (c) a pore-forming agent; and (d) a plasticizer.
    Type: Application
    Filed: November 29, 2023
    Publication date: April 25, 2024
    Applicant: SLAYBACK PHARMA LLC
    Inventors: Sushant Omprakash DUBE, Suprit Dilip SAOJI, Pankaj Kisan CHATKI, Sumitra Ashokkumar PILLAI, Girish G. KORE
  • Patent number: 11957685
    Abstract: Liquid pharmaceutical compositions of tofacitinib or its pharmaceutically acceptable salts thereof are described, which are suitable for oral administration, and which are stable under varying storage conditions for extended periods of time. Methods of treating auto-immune disorders are also described, using the stable liquid pharmaceutical compositions of tofacitinib. A stable liquid pharmaceutical composition of tofacitinib according to the invention comprises of (a) tofacitinib at a concentration of about 1 mg/mL or more; (b) a pharmaceutically acceptable liquid vehicle; (c) at least one anti-oxidant; and (d) optionally one or more other pharmaceutically acceptable excipients.
    Type: Grant
    Filed: August 10, 2023
    Date of Patent: April 16, 2024
    Assignee: SLAYBACK PHARMA LLC
    Inventors: Sushant Omprakash Dube, Purushottam Dattatraya Kulkarni, Purushottam Sakhahari Pattewar, Sumitra Ashokkumar Pillai
  • Publication number: 20240050416
    Abstract: The present invention relates to stable pharmaceutical compositions comprising apixaban or its pharmaceutically acceptable salts thereof. The present invention further relates to a capsule composition comprising a therapeutically effective amount of apixaban solubilized or dispersed in a pharmaceutically acceptable carrier, wherein the therapeutically effective amount of apixaban ranges from about 0.5 mg/unit dosage form to about 50 mg/unit dosage form. The present invention also provides manufacturing processes thereof and use of the said compositions for prevention, treatment or prophylaxis of disorders in human patients in need thereof.
    Type: Application
    Filed: July 24, 2023
    Publication date: February 15, 2024
    Applicant: Slayback Pharma LLC
    Inventors: Shailendra Mandge, Venkateshwar Reddy Keesara, Harish Gunda, Naga Venkata Durga Prasad Ketha, Satheesh Balasubramanian, Sumitra Ashokkumar Pillai, Sushant Omprakash Dube, Praveen Kumar Subbappa
  • Publication number: 20240016771
    Abstract: The present invention relates to stable liquid pharmaceutical compositions of baclofen or a pharmaceutically acceptable salt thereof. More specifically, stable oral suspensions of baclofen at concentrations of equal to or more than 2 mg/mL or more are provided. Preferably, the liquid pharmaceutical compositions of baclofen are suitable for oral administration and are stable at wider pH ranges over a variety of storage conditions, including long-term storage for extended periods of time. Methods of treating various disorders using the inventive pharmaceutical compositions are also provided. The invention further relates to various methods for preparing stable suspension of baclofen.
    Type: Application
    Filed: September 26, 2023
    Publication date: January 18, 2024
    Applicant: ANI Pharmaceuticals, Inc.
    Inventors: Sushant Omprakash Dube, Purushottam Sakhahari Pattewar, Pankaj Kisan Chatki, Sumitra Ashokkumar Pillai
  • Patent number: 11857524
    Abstract: The present invention relates to stable liquid pharmaceutical compositions of baclofen or a pharmaceutically acceptable salt thereof. More specifically, stable oral suspensions of baclofen at concentrations of equal to or more than 2 mg/mL or more are provided. Preferably, the liquid pharmaceutical compositions of baclofen are suitable for oral administration and are stable at wider pH ranges over a variety of storage conditions, including long-term storage for extended periods of time. Methods of treating various disorders using the inventive pharmaceutical compositions are also provided. The invention further relates to various methods for preparing stable suspension of baclofen.
    Type: Grant
    Filed: April 4, 2023
    Date of Patent: January 2, 2024
    Assignee: ANI Pharmaceuticals, Inc.
    Inventors: Sushant Omprakash Dube, Purushottam Sakhahari Pattewar, Pankaj Kisan Chatki, Sumitra Ashokkumar Pillai
  • Publication number: 20230398120
    Abstract: Liquid pharmaceutical compositions of tofacitinib or its pharmaceutically acceptable salts thereof are described, which are suitable for oral administration, and which are stable under varying storage conditions for extended periods of time. Methods of treating auto-immune disorders are also described, using the stable liquid pharmaceutical compositions of tofacitinib. A stable liquid pharmaceutical composition of tofacitinib according to the invention comprises of (a) tofacitinib at a concentration of about 1 mg/mL or more; (b) a pharmaceutically acceptable liquid vehicle; (c) at least one anti-oxidant; and (d) optionally one or more other pharmaceutically acceptable excipients.
    Type: Application
    Filed: August 10, 2023
    Publication date: December 14, 2023
    Applicant: SLAYBACK PHARMA LLC
    Inventors: Sushant Omprakash DUBE, Purushottam Dattatraya KULKARNI, Purushottam Sakhahari PATTEWAR, Sumitra Ashokkumar PILLAI
  • Patent number: 11766438
    Abstract: The present invention relates to liquid pharmaceutical compositions of tofacitinib or its pharmaceutically acceptable salts thereof, suitable for oral administration, that are stable under varying storage conditions for extended periods of time. The present invention also relates to methods of treating auto-immune disorders using the stable liquid pharmaceutical compositions of tofacitinib. A stable liquid pharmaceutical composition of tofacitinib according to the invention comprises of (a) tofacitinib at a concentration of about 1 mg/mL or more; (b) a pharmaceutically acceptable liquid vehicle; (c) at least one anti-oxidant; and (d) optionally one or more other pharmaceutically acceptable excipients.
    Type: Grant
    Filed: April 23, 2021
    Date of Patent: September 26, 2023
    Assignee: SLAYBACK PHARMA LLC
    Inventors: Sushant Omprakash Dube, Purushottam Dattatraya Kulkarni, Purushottam Sakhahari Pattewar, Sumitra Ashokkumar Pillai
  • Publication number: 20230285341
    Abstract: The present invention relates to stable liquid pharmaceutical compositions of baclofen or a pharmaceutically acceptable salt thereof. More specifically, stable oral suspensions of baclofen at concentrations of equal to or more than 2 mg/mL or more are provided. Preferably, the liquid pharmaceutical compositions of baclofen are suitable for oral administration and are stable at wider pH ranges over a variety of storage conditions, including long-term storage for extended periods of time. Methods of treating various disorders using the inventive pharmaceutical compositions are also provided. The invention further relates to various methods for preparing stable suspension of baclofen.
    Type: Application
    Filed: April 4, 2023
    Publication date: September 14, 2023
    Applicant: SLAYBACK PHARMA LLC
    Inventors: Sushant Omprakash Dube, Purushottam Sakhahari Pattewar, Pankaj Kisan Chatki, Sumitra Ashokkumar Pillai
  • Publication number: 20230285368
    Abstract: Liquid pharmaceutical compositions of apixaban or pharmaceutically acceptable salts thereof are described. More specifically, stable oral liquid pharmaceutical compositions of apixaban for oral administration are provided, wherein the composition is stable for extended periods of time. More specifically, stable liquid pharmaceutical compositions of apixaban at concentrations of 0.4 mg/mL or more are provided. Stable oral liquid compositions of apixaban, methods for their administration, processes for their production, and use of these compositions for treatment of diseases treatable by apixaban are disclosed.
    Type: Application
    Filed: March 6, 2023
    Publication date: September 14, 2023
    Applicant: Slayback Pharma LLC
    Inventors: Sushant Omprakash Dube, Girish G. Kore, Naga Venkata Durga Prasad Ketha, Sumitra Ashokkumar Pillai, Praveen Kumar Subbappa
  • Publication number: 20230270736
    Abstract: Pharmaceutical compositions are provided, which comprise cabozantinib or pharmaceutically acceptable salts thereof, and at least one pharmaceutically acceptable excipient, wherein the inventive compositions exhibit enhanced bioavailability compared to the currently marketed or commercially available formulations. The present invention also provides manufacturing processes thereof and use of the said inventive compositions for the prevention, treatment or prophylaxis of disorders in human patients in need thereof. The present invention relates to oral pharmaceutical compositions of cabozantinib, methods for their administration, processes for their production, and use of these compositions for treatment of diseases treatable by cabozantinib.
    Type: Application
    Filed: May 5, 2023
    Publication date: August 31, 2023
    Applicant: SLAYBACK PHARMA LLC
    Inventors: Sushant Omprakash DUBE, Suprit Dilip SAOJI, Pankaj Kisan CHATKI, Sumitra Ashokkumar PILLAI, Girish G. KORE