Abstract: An RF treatment device according to the present invention includes one or two radio frequency electrode holders each having multiple needle electrodes arranged to create a transmural lesion through tissue, with or without the presence of fat on the tissue. When inserted through the tissue, the needle electrodes are in single straight or curved line with the needle electrodes being parallel to each other, adjacent electrodes having opposite polarity, and having tips and shafts designed to minimize tissue penetration force. Lubricious coatings may be provided for this purpose, along with or in lieu of motion imparting mechanisms which to impart vibration, oscillation, or rotation which facilitate penetration. Further, RF energy may applied during penetration for this purpose. The embodiments are described for use in creating a transmural lesion in heart tissue to treat atrial fibrillation by blocking the passage of abnormal electrical currents through the heart.