Patents by Inventor Susri Ray Chaudhuri

Susri Ray Chaudhuri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3-indolyl furanoids as inhibitors of matrix metalloproteinase-9 for prevention of gastric ulcer and other inflammatory diseases
    Patent number: 10590116
    Abstract: Disclosed are 3-indolyl furanoid compounds which are useful as potent anti-inflammatory agents and prevent gastric ulcer by inhibiting matrix metalloproteinase-9 (MMP-9) expression in gastric mucosal layer. For example, disclosed is a compound of formula 1, wherein: R1 to R6 is selected from H, OH, CH3, OCH3, Br, Cl, Ph or o-OHC6H4, OCH2—CH?CH2, or OCH2CH2CH3, and R1 to R6 is having at least one substituent with alkyl, aryl and heteroaryl groups other than H, wherein the carbon in alkyl, aryl and heteroaryl is in the range of C1 to C8. Various embodiments relate to representative compounds of Formula 1 and method of preparation thereof. Further embodiments relates to the use of representative compounds of Formula 1 in treating diseases associated with gastric ulcer and other inflammatory diseases. A noted feature of an embodiment is the IC50 value of 50 ?M of one of the 3-indolyl furanoids.
    Type: Grant
    Filed: February 15, 2018
    Date of Patent: March 17, 2020
    Assignee: Council of Scientific & Industrial Research
    Inventors: Parasuraman Jaisankar, Snehasikta Swarnakar, Sourav Chatterjee, Sugreev Verma, Madhumita Mandal, Susri Ray Chaudhuri
  • 3-INDOLYL FURANOIDS AS INHIBITORS OF MATRIX METALLOPROTEINASE-9 FOR PREVENTION OF GASTRIC ULCER AND OTHER INFLAMMATORY DISEASES
    Publication number: 20180230135
    Abstract: Disclosed are 3-indolyl furanoid compounds which are useful as potent anti-inflammatory agents and prevent gastric ulcer by inhibiting matrix metalloproteinase-9 (MMP-9) expression in gastric mucosal layer. For example, disclosed is a compound of formula 1, wherein: R1 to R6 is selected from H, OH, CH3, OCH3, Br, Cl, Ph or o-OHC6H4, OCH2—CH?CH2, or OCH2CH2CH3, and R1 to R6 is having at least one substituent with alkyl, aryl and heteroaryl groups other than H, wherein the carbon in alkyl, aryl and heteroaryl is in the range of C1 to C8. Various embodiments relate to representative compounds of Formula 1 and method of preparation thereof. Further embodiments relates to the use of representative compounds of Formula 1 in treating diseases associated with gastric ulcer and other inflammatory diseases. A noted feature of an embodiment is the IC50 value of 50 ?M of one of the 3-indolyl furanoids.
    Type: Application
    Filed: February 15, 2018
    Publication date: August 16, 2018
    Inventors: Parasuraman Jaisankar, Snehasikta Swarnakar, Sourav Chatterjee, Sugreev Verma, Madhumita Mandal, Susri Ray Chaudhuri