Abstract: An analytical system for detecting a saccharide is provided. The analytical system includes a saccharide sensor attached to a solid substrate and having the formula: Where Z is selected from the group consisting of hydrogen, alkyl groups, an aryl; N is a nitrogen atom; Bd1 and Bd2 are independently selected binding groups, wherein the binding groups are capable of binding an saccharide; Sp is a spacer; An is an anchor group for attaching the sensor to solid substrate, including a bead; and n=1 or 2, m=1 or 2, y=1 or 2, and p is an integer. In one embodiment the saccharide sensor preferentially detects glucose. The invention further provides beads having the saccharide sensor attached thereto and methods of detecting glucose using the system.

Abstract: An analytical system for detecting a saccharide is provided.

Abstract: Disclosed is a modular fluorescence sensor having the following general formula: Where Fl is a fluorophore, N is a nitrogen atom, Bd1 and Bd2 are independently selected binding groups, Sp is an aliphatic spacer, and An is an anchor group for attaching the sensor to solid substrates. n=1 or 2, m=1 or 2, x is an integer, and y=1 or 2. The binding groups are capable of binding an analyte molecule to form a stable 1:1 complex. In a preferred embodiment, the Bd1 is R1—B(OH)2 and Bd2 is R2—B(OH)2. R1 and R2 are aliphatic or aromatic functional groups selected independently from each other and B is a boron atom. The present invention also provides methods of synthesizing a modular fluorescence sensor and its use in labeling solid substrates.

Abstract: The invention provides compounds for detecting sacchharides by electrochemistry. The compounds have a structure that includes a first boronic acid group attached by a first linker group to a first tertiary amine. The first tertiary amine is attached to a reporter group that includes an organometalic reporter moiety. A spacer group attaches the first tertiary amine to a second tertiary amine. The second tertiary amine is attached to an R group and a second linker group. The second linker group is attached to a second boronic acid group. In preferred embodiments, the compound selectively detects glucose and has a higher relative stability constant for glucose than for other saccharides.

Abstract: The invention provides compounds for detecting sacchharides by electrochemistry. The compounds have a structure that includes a first boronic acid group attached by a first linker group to a first tertiary amine. The first tertiary amine is attached to a reporter group that includes an organometalic reporter moiety. A spacer group attaches the first tertiary amine to a second tertiary amine. The second tertiary amine is attached to an R group and a second linker group. The second linker group is attached to a second boronic acid group. In preferred embodiments, the compound selectively detects glucose and has a higher relative stability constant for glucose than for other saccharides.

Abstract: Disclosed is a modular fluorescence sensor having the following general formula: 1

Abstract: Disclosed is a modular fluorescence sensor having the following general formula: where Fl is a fluorophore, N is a nitrogen atom, Bd1 and Bd2 are independently selected binding groups, Sp is an aliphatic spacer, and An is an anchor group for attaching the sensor to solid substrates. n=1 or 2, m=1 or 2, x is an integer, and y=1 or 2. The binding groups are capable of binding an analyte molecule to form a stable 1:1 complex. In a preferred embodiment, the Bd1 is R1—B(OH)2 and Bd2 is R2—B(OH)2. R1 and R2 are aliphatic or aromatic functional groups selected independently from each other and B is a boron atom. The present invention also provides methods of synthesizing a modular fluorescence sensor and its use in labeling solid substrates.

Abstract: The invention provides an antibacterial polymeric molded product containing an anionic compound capable of combining, by ionic bond, with a cationic component of a water-soluble antibacterial agent, wherein the cationic component is combined with the anionic compound by ionic bond at least at the surface of the molded product.

Abstract: Tpresent invention provide a biocompatible polyurethane or oplyurethane urea containing, in the side chain, phosphorylcholine structure represented by the formula (1) ##STR1## wherein R.sup.1 is C.sub.1-20 alkyl, C.sub.6-12 aryl, C.sub.7-20 aralkyl or a group of the formula:R.sup.4 -(A).sub.n -(wherein A is C.sub.2-10 oxyalkylene, and (A).sub.n may be constituted of one kind of oxyalkylene groups or of two or more kinds of oxyalkylene groups linked together in blocks or at random; n is an integer of 1 to 30; and R.sup.4 is C.sub.1-20 alkyl, C.sub.6-12 aryl or C.sub.7-20 aralkyl); and R.sup.2 and R.sup.3 each represent C.sub.1-20 alkyl, C.sub.6-12 aryl or C.sub.7-20 aralkyl and may be the same or different; and an antithrombogenic medical product prepared using the polyurethane or polyurethane urea.

Abstract: The present invention relates to an organic solvent-soluble mucopolysaccharide consisting of an ionic complex of at least one mucopolysaccharide (preferably heparin or heparin derivative) and a quaternary phosphonium, an antibacterial antithrombogenic composition comprising said organic solvent-soluble mucopolysaccharide and an organic polymer material, an antibacterial antithrombogenic composition comprising said organic solvent-soluble mucopolysaccharide and an antibacterial agent (preferably inorganic antibacterial agent such as silver zeolite), and to a medical material comprising said organic solvent-soluble mucopolysaccharide.