Abstract: Provided is a means for identifying cells suitable for transplantation into a cornea, or a means for producing a cell population suitable for transplantation into a cornea using the same. A method for producing a cell population suitable for transplantation into a cornea, the method comprising the steps of (1) preparing a cell population cultured under conditions suitable for inducing differentiation into corneal endothelial cells, and (2) measuring the expression of at least one gene selected from the group consisting of POU6F2, LMX1B, and TFAP2B in the cell population.

Abstract: A molecular marker expressed specifically in corneal endothelial cells, and a method for producing one or more corneal endothelial cells using the marker and a method for evaluating one or more corneal endothelial cells using the marker are provided. At least one molecule selected from the group consisting of ZP4, MRGPRX3, GRIP1, GLP1R, HTR1D, and CLRN1 is used as a marker specific to corneal endothelial cells.

Abstract: Legwear in accordance with an embodiment of the present invention includes a stretchable main body part including an innermost-toe joint side region and an outermost-toe joint side region and a low-stretching part provided around the innermost-toe joint side region and the outermost-toe joint side region and configured to prevent the regions from becoming displaced relative to a foot in a downward direction or a front-back direction. The low-stretching part at least either is less stretchable than the main body part or has larger friction with the foot than the main body part has with the foot.

Abstract: Provided is a means for identifying cells suitable for transplantation into a cornea, or a means for producing a cell population suitable for transplantation into a cornea using the same. A method for producing a cell population suitable for transplantation into a cornea, the method comprising the steps of (1) preparing a cell population cultured under conditions suitable for inducing differentiation into corneal endothelial cells, and (2) measuring the expression of at least one gene selected from the group consisting of POU6F2, LMX1B, and TFAP2B in the cell population.

Abstract: A molecular marker expressed specifically in corneal endothelial cells, and a method for producing one or more corneal endothelial cells using the marker and a method for evaluating one or more corneal endothelial cells using the marker are provided. At least one molecule selected from the group consisting of ZP4, MRGPRX3, GRIP1, GLP1R, HTR1D, and CLRN1 is used as a marker specific to corneal endothelial cells.

Abstract: The present invention provides a pad capable of effectively curbing fall of a plantar arch. A pad in accordance with the present embodiment, for supporting the plantar arch of a sole of a foot, is provided in a supporter, made of a stretch cloth, including a plantar part and an instep part, which is connected to the plantar part. The pad is located in the plantar part and has an apex, which is provided at a position corresponding to an area in the sole of the foot which area corresponds to the navicular bone of the foot.

Abstract: A foot cover in accordance with an embodiment includes: a main body part including a sole part which covers a sole and a heel part which covers a heel; and a nonslip part provided on an inside of the heel part which inside faces a back surface of the heel, the nonslip part having elasticity lower than that of a cloth of the heel part. The nonslip part includes strip-shaped parts which prevent the cloth of the heel part from expanding and contracting in a vertical direction and a horizontal direction.

Abstract: The present invention relates to a method for preparing corneal endothelial progenitor cells by adherent culturing a cell population isolated from corneal endothelial cell tissue at a low density by using a serum-free medium. The present invention also relates to a method for preparing corneal endothelial cells by differentiation-inducing the corneal endothelial progenitor cells obtained by the aforementioned method. According to the present invention, corneal endothelial progenitor cells can be selectively grown from a corneal tissue-derived cell population, and corneal endothelial cells obtained by inducing the corneal endothelial progenitor cells can be applied to treatment of corneal endothelial diseases. As a result, problems of corneal transplantation such as shortage of donors and occurrence of rejection can be solved.

Abstract: A three-dimensional rectangular coordinate system is set in which the direction of a weld line is the Y direction, a direction perpendicular to a surface of a material to be welded is the Z direction, and a direction perpendicular to the Y direction and the Z direction is the X direction. A coordinate system A of XAYAZA is set as a previous stage coordinate system, which ranges from a previous step to a current step, and a coordinate system B of XBYBZB is set as a next stage coordinate system, which ranges from the current step to a next step. The weld line is defined by these coordinate systems that use a workpiece as a reference, and an operator specifies the amount of travel of a torch in these workpiece coordinate systems. By this method, offline teaching can be accurately performed in a welding system without requiring skill in operation.

Abstract: A cascaded phase-locked loop (PLL) clock generation technique reduces frequency drift of a low-jitter clock signal in a holdover mode. An apparatus includes a first PLL circuit configured to generate a control signal based on a first clock signal and a first divider value. The apparatus includes a second PLL circuit configured to generate the first clock signal based on a low-jitter clock signal and a second divider value. The apparatus includes a third PLL circuit configured to generate the second divider value based on the first clock signal, a third divider value, and a second clock signal. The low-jitter clock signal may have a greater temperature dependence than the second clock signal and the second clock signal may have a higher jitter than the low-jitter clock signal.

Abstract: A cascaded phase-locked loop (PLL) clock generation technique reduces frequency drift of a low-jitter clock signal in a holdover mode. An apparatus includes a first PLL circuit configured to generate a control signal based on a first clock signal and a first divider value. The apparatus includes a second PLL circuit configured to generate the first clock signal based on a low-jitter clock signal and a second divider value. The apparatus includes a third PLL circuit configured to generate the second divider value based on the first clock signal, a third divider value, and a second clock signal. The low-jitter clock signal may have a greater temperature dependence than the second clock signal and the second clock signal may have a higher jitter than the low-jitter clock signal.

Abstract: The present invention relates to a method for preparing corneal endothelial progenitor cells by adherent culturing a cell population isolated from corneal endothelial cell tissue at a low density by using a serum-free medium. The present invention also relates to a method for preparing corneal endothelial cells by differentiation-inducing the corneal endothelial progenitor cells obtained by the aforementioned method. According to the present invention, corneal endothelial progenitor cells can be selectively grown from a corneal tissue-derived cell population, and corneal endothelial cells obtained by inducing the corneal endothelial progenitor cells can be applied to treatment of corneal endothelial diseases. As a result, problems of corneal transplantation such as shortage of donors and occurrence of rejection can be solved.

Abstract: A flexible clock synthesizer technique includes generating a phase interpolator calibration signal to adjust a phase interpolator output signal generated by a phase interpolator of an interpolative divider. The phase interpolator is responsive to a phase interpolator control code and an output signal of a fractional-N divider of the interpolative divider. The phase interpolator calibration signal is based on an error signal indicative of a phase interpolator error. The error signal may indicate a phase relationship between a reference clock signal and a feedback clock signal of a PLL. The interpolative divider may be coupled in a feedback path of the PLL. The PLL may receive a reference clock signal and the feedback clock signal may be an adjusted phase interpolator output signal. The phase interpolator calibration signal may be a phase interpolator offset code corresponding to the phase interpolator control code or a phase interpolator gain signal.

Abstract: A flexible clock synthesizer technique includes generating a phase interpolator calibration signal to adjust a phase interpolator output signal generated by a phase interpolator of an interpolative divider. The phase interpolator is responsive to a phase interpolator control code and an output signal of a fractional-N divider of the interpolative divider. The phase interpolator calibration signal is based on an error signal indicative of a phase interpolator error. The error signal may indicate a phase relationship between a reference clock signal and a feedback clock signal of a PLL. The interpolative divider may be coupled in a feedback path of the PLL. The PLL may receive a reference clock signal and the feedback clock signal may be an adjusted phase interpolator output signal. The phase interpolator calibration signal may be a phase interpolator offset code corresponding to the phase interpolator control code or a phase interpolator gain signal.

Abstract: An apparatus includes a first conductive loop coupled to conduct a first current and a second conductive loop coupled in parallel with the first conductive loop and further coupled to conduct a second current. A first conductive portion forms a part of the first conductive loop and the second conductive loop. The first conductive portion is coupled to conduct the first current and the second current. In at least one embodiment of the apparatus, the first conductive loop and the second conductive loop are planar inductors formed in a conductive layer on a substrate of an integrated circuit.

Abstract: One or more PLLs are formed on an integrated circuit. Each PLL includes an interpolative divider configured as a digitally controlled oscillator, which receives a reference clock signal and supplies an output signal divided according to a divide ratio. A feedback divider is coupled to the output signal of the interpolative divider and supplies a divided output signal as a feedback signal. A phase detector receives the feedback signal and a clock signal to which the PLL locks. The phase detector supplies a phase error corresponding to a difference between the clock signal and the feedback signal and the divide ratio is adjusted according to the phase error.

Abstract: An apparatus includes a first conductive loop coupled to conduct a first current and a second conductive loop coupled in parallel with the first conductive loop and further coupled to conduct a second current. A first conductive portion forms a part of the first conductive loop and the second conductive loop. The first conductive portion is coupled to conduct the first current and the second current. In at least one embodiment of the apparatus, the first conductive loop and the second conductive loop are planar inductors formed in a conductive layer on a substrate of an integrated circuit.