Patents by Inventor Suyu Shu

Suyu Shu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8247227
    Abstract: A method of generating a population of dendritic cell (DC) precursors includes obtaining a population of progenitor cells from a subject and culturing the progenitor cells in a culture medium. The culture medium can include Flt3 ligand and interleukin-6 and be free of granulocyte-macrophage colony-stimulating factor.
    Type: Grant
    Filed: August 28, 2007
    Date of Patent: August 21, 2012
    Assignees: The Cleveland Clinic Foundation, Trustees of the University of Pennsylvania, National Institutes of Health
    Inventors: Peter A. Cohen, Suyu Shu, Gary K. Koski, Charles S. Carter, Laura Carter, legal representative, Brian J. Czerniecki
  • Publication number: 20100272700
    Abstract: A method of generating a population of dendritic cell (DC) precursors includes obtaining a population of progenitor cells from a subject and culturing the progenitor cells in a culture medium. The culture medium can include Flt3 ligand and interleukin-6 and be free of granulocyte-macrophage colony-stimulating factor.
    Type: Application
    Filed: August 28, 2007
    Publication date: October 28, 2010
    Inventors: Peter A. Cohen, Suyu Shu, Gary K. Koski, Charles S. Carter, Brian J. Czerniecki
  • Publication number: 20030082163
    Abstract: A method and apparatus for electrofusing a plurality of cancer cell types to dendritic cells (DCs) which results in the formation of electrofused DC-tumor cells with high efficiency and high viability. The method comprises subjecting the cells with multiple pulses of voltage in specially designed media. This is the first documentation of electrofusion of large numbers of DCs and tumor cells. Evidence demonstrates those cells contain all essential DC molecules and express tumor antigens. A single vaccination of animals with pre-existing tumors results in substantial erradication of tumors and cure of animals. The electrofused-cells can be used immediately. These fusion hybrids are to be used for the treatment of cancer directly as vaccines or indirectly by activating immune lymphocytes for adoptive immunotherapy.
    Type: Application
    Filed: October 25, 2002
    Publication date: May 1, 2003
    Inventor: Suyu Shu