Patents by Inventor Suzane L. Topalian

Suzane L. Topalian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MHC-class II restricted melanoma antigens and their use in therapeutic methods
    Patent number: 6951917
    Abstract: The present invention provides MHC Class II restricted melanoma antigens recognized by CD4+ T cells. This invention further provides prophylactic and therapeutic applications for the Class II restricted melanoma antigens. In particular, this invention provides tyrosinase Class II restricted melanoma antigens, as well as tyrosinase immunogenic peptides which have been modified to enhance their immunogenicity. These antigens can serve as an immunogens or vaccines to prevent or treat melanoma. In addition a method for isolating Class II restricted melanoma antigens or identifying new Class II restricted melanoma antigens is provided.
    Type: Grant
    Filed: September 26, 1995
    Date of Patent: October 4, 2005
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Suzane L. Topalian, Steven A. Rosenberg, Paul F. Robbins