Abstract: The invention is directed to a method of cleaning and disinfecting a contact lens. The method includes instructing a consumer to disinfect their contact lens comprising the following steps: remove a contact from an eye and position the lens in a lens assembly that includes a cap member; add a disinfection solution to the lens case such that the lens is submerged in the solution upon closure of the lens case with the cap member. The disinfection solution will comprise 0.5 wt. % to 6 wt. % hydrogen peroxide or a chemical precursor of hydrogen peroxide, and a P-metal modulating compound. The presence of the P-metal modulating compound in the disinfection solution decreases the neutralization rate of the hydrogen peroxide. The disinfection system exhibits a pseudo first-order, half-life of hydrogen peroxide from 12 minutes to 30 minutes over an initial sixty minutes of neutralization following exposure of the disinfection solution to a catalyst comprising a P-metal.

Abstract: The invention is directed to a method of cleaning and disinfecting a contact lens. The method includes instructing a consumer to disinfect their contact lens comprising the following steps: remove a contact from an eye and position the lens in a lens assembly that includes a cap member; add a disinfection solution to the lens case such that the lens is submerged in the solution upon closure of the lens case with the cap member. The disinfection solution will comprise 0.5 wt. % to 6 wt. % hydrogen peroxide or a chemical precursor of hydrogen peroxide, and a P-metal modulating compound. The presence of the P-metal modulating compound in the disinfection solution decreases the neutralization rate of the hydrogen peroxide. The disinfection system exhibits a pseudo first-order, half-life of hydrogen peroxide from 12 minutes to 30 minutes over an initial sixty minutes of neutralization following exposure of the disinfection solution to a catalyst comprising a P-metal.

Abstract: A contact lens disinfecting solution that comprises 0.5 wt. % to 6 wt. % hydrogen peroxide, or a chemical precursor of hydrogen peroxide, and a P-metal modulating compound. The presence of the P-metal modulating compound in the disinfecting hydrogen peroxide solution slows the rate at which the hydrogen peroxide is neutralized, particularly during the initial two hours, by a catalyst element that includes a P-metal. This reduction in rate of peroxide neutralization provides a more effective solution for killing certain microorganisms and fungi.

Abstract: A contact lens disinfecting solution that comprises 0.5 wt. % to 6 wt. % hydrogen peroxide, or a chemical precursor of hydrogen peroxide, and a P-metal modulating compound. The presence of the P-metal modulating compound in the disinfecting hydrogen peroxide solution slows the rate at which the hydrogen peroxide is neutralized, particularly during the initial two hours, by a catalyst element that includes a P-metal. This reduction in rate of peroxide neutralization provides a more effective solution for killing certain microorganisms and fungi.

Abstract: Contact lens cases for delivering ophthalmic active agents to contact lenses. A contact lens case includes a container defining a reservoir for soaking a contact lens in a solution, and a lid assembly that may be secured to the container for closing the reservoir. The lid assembly includes a lid and a dispenser pack. The dispenser pack includes one or more compartments containing a treatment unit which may be dispensed from the compartment(s) into the solution. After the contact lens soaks in solution and retains or absorbs a suitable amount of the ophthalmic agent from the treatment unit, the contact lens is inserted in a user's eye for treating the eye.

Abstract: A method of making a disinfecting solution that is effective at disinfecting contact lenses. The method includes the step of combining water, one or more antimicrobial agents and a reduced amount of solid content into a dissolved liquid mixture. The process results in an improved disinfection efficacy compared to a reference solution.

Abstract: An in-eye method for cleaning contact lenses comprises use of a cleaner using water-containing beads. The water-containing beads are prepared such that the bead size is smaller than the punctual opening. They are easily flushed from the ocular environment by normal tear flow. The cleaner may also be used to clean contact lenses, with the cleaner applied directly to the lens and digitally rubbed to remove accumulated debris on the lens.

Abstract: An in-eye method for cleaning contact lenses comprises use of a cleaner using water-containing beads. The water-containing beads are prepared such that the bead size is smaller than the punctal opening. They are easily flushed from the ocular environment by normal tear flow. The cleaner may also be used to clean contact lenses, with the cleaner applied directly to the lens and digitally rubbed to remove accumulated debris on the lens.

Abstract: The present invention provides an optically clear, hydrophilic coating upon the surface of a non-plasma treated hydrophobic hydrogel lens by heating the lens in an aqueous solution containing a surface-protective agent. Alternately, the non-plasma treated hydrophobic hydrogel lens may be subjected to ultrasonication while immersed in an aqueous solution containing a surface-protective agent.

Abstract: An aqueous composition for cleaning and wetting a contact lens includes: a non-amine polyethyleneoxy-containing material having an HLB value of at least about 18; a first non-ionic surface active agent having cleaning activity for contact lens deposits that comprises a poloxamine; c) a second non-ionic surface active agent having cleaning activity for contact lens deposits and that comprises a non- poloxamine surface active agent; and a wetting agent.

Abstract: The present invention provides an optically clear, hydrophilic coating upon the surface of a silicone hydrogel lens by plasma treating the lens and subsequently heating the lens in an aqueous solution containing a surface-protective agent.

Abstract: A cleaning solution for contact lenses is described that includes a carbohydrate that is a mono- or disaccharide, its alcohols or partially hydrolyzed esters or mixtures thereof. Preferred carbohydrates are sorbitol, glucose, maltose, sucrose, dulcitol, dextran, dextrin, mannitol, maltitol, or mannose, preferably in an amount of 0.001 to 10% by weight of an aqueous solution for cleaning the contact lenses. A preferred composition for cleaning contact lenses comprises sorbitol in an amount of about 0.1 to 1% by weight in an aqueous solution. A method for cleaning contact lenses with said carbohydrate cleaning solution is described and may be combined, for simultaneously cleaning and disinfecting contact lenses, with a chemical, antimicrobial agent or thermal disinfecting regimen.

Abstract: The present invention provides methods for treating contact lenses and compositions for the same. The present invention includes contacting a lens with an aqueous solution comprising a sulfobetaine compound represented by the formula: ##STR1## wherein: R.sub.1 is an alkyl group having from 8 to 30 carbon atoms, R.sub.2 and R.sub.3 are individually hydrogen or alkyl groups having from 1 to 4 carbon atoms, and R.sub.4 is an alkyl group having from 2 to 6 carbon atoms. In preferred embodiments of the invention, the subject compounds are used in combination with antimicrobial agents for providing simultaneous disinfection and cleaning of contact lenses.

Abstract: Contact lenses are cleaned by contacting the lenses with a composition containing an effective amount of one or more cyclodextrins. The compositions can also be employed at elevated temperatures or may contain suitable antimicrobial agents in order to simultaneously clean and disinfect the lenses.